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  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

Neuroanatomical correlates of attention-deficit-hyperactivity disorder accounting for comorbid oppositional defiant disorder and conduct disorder

http://hdl.handle.net/10091/16891
http://hdl.handle.net/10091/16891
84f9f63d-1e84-4462-89fa-c0cd9dde6d30
名前 / ファイル ライセンス アクション
Neuroanatomical_correlates_attention_deficit_hyperactivity_disorder_accounting.pdf Neuroanatomical_correlates_attention_deficit_hyperactivity_disorder_accounting.pdf (287.2 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2013-04-01
タイトル
タイトル Neuroanatomical correlates of attention-deficit-hyperactivity disorder accounting for comorbid oppositional defiant disorder and conduct disorder
言語
言語 eng
DOI
関連識別子 https://doi.org/10.1111/j.1440-1819.2010.02102.x
関連名称 10.1111/j.1440-1819.2010.02102.x
キーワード
主題 attention deficit hyperactivity disorder, brain, magnetic resonance imaging, voxel-based morphometry
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Sasayama, Daimei

× Sasayama, Daimei

en Sasayama, Daimei

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Hayashida, Ayako

× Hayashida, Ayako

en Hayashida, Ayako

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Yamasue, Hidenori

× Yamasue, Hidenori

en Yamasue, Hidenori

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Harada, Yuzuru

× Harada, Yuzuru

en Harada, Yuzuru

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Kaneko, Tomoki

× Kaneko, Tomoki

en Kaneko, Tomoki

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Kasai, Kiyoto

× Kasai, Kiyoto

en Kasai, Kiyoto

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Washizuka, Shinsuke

× Washizuka, Shinsuke

en Washizuka, Shinsuke

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Amano, Naoji

× Amano, Naoji

en Amano, Naoji

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信州大学研究者総覧へのリンク
氏名 Sasayama, Daimei
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.uNkegpkh.html
信州大学研究者総覧へのリンク
氏名 Harada, Yuzuru
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.yFcCuUkh.html
信州大学研究者総覧へのリンク
氏名 Kaneko, Tomoki
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.WayFuakh.html
信州大学研究者総覧へのリンク
氏名 Washizuka, Shinsuke
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.uhnNuakh.html
出版者
出版者 WILEY-BLACKWELL
引用
内容記述 PSYCHIATRY AND CLINICAL NEUROSCIENCES. 64(4):394-402 (2010)
書誌情報 PSYCHIATRY AND CLINICAL NEUROSCIENCES

巻 64, 号 4, p. 394-402, 発行日 2010
抄録
内容記述 Aim: An increasing number of neuroimaging studies have been conducted to uncover the pathophysiology of attention-deficit-hyperactivity disorder (ADHD). The findings are inconsistent, however, at least partially due to methodological differences. In the present study voxel-based morphometry (VBM) was used to evaluate brain morphology in ADHD subjects after taking into account the confounding effect of oppositional defiant disorder (ODD) and conduct disorder (CD) comorbidity. Methods: Eighteen children with ADHD and 17 age-and gender-matched typically developing subjects underwent high-spatial resolution magnetic resonance imaging. The regional gray matter volume differences between the children with ADHD and controls were examined with and without accounting for comorbid ODD and CD in a voxel-by-voxel manner throughout the entire brain. Results: The VBM indicated significantly smaller regional gray matter volume in regions including the bilateral temporal polar and occipital cortices and the left amygdala in subjects with ADHD compared with controls. Significantly smaller regional gray matter volumes were demonstrated in more extensive regions including the bilateral temporal polar cortices, bilateral amygdala, right occipital cortex, right superior temporal sulcus, and left middle frontal gyrus after controlling for the confounding effect of comorbid ODD and CD. Conclusion: Morphological abnormalities in ADHD were seen not only in the regions associated with executive functioning but also in the regions associated with social cognition. When the effect of comorbid CD and ODD was taken into account, there were more extensive regions with significantly smaller volume in ADHD compared to controls.
資源タイプ(コンテンツの種類)
ISSN
収録物識別子タイプ PISSN
収録物識別子 1323-1316
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA11040669
PubMed
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/20546170
関連名称 20546170
権利
権利情報 The definitive version is available at www.wileyonlinelibrary.com
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000280355800007
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Cite as

Sasayama, Daimei, Hayashida, Ayako, Yamasue, Hidenori, Harada, Yuzuru, Kaneko, Tomoki, Kasai, Kiyoto, Washizuka, Shinsuke, Amano, Naoji, 2010, Neuroanatomical correlates of attention-deficit-hyperactivity disorder accounting for comorbid oppositional defiant disorder and conduct disorder: WILEY-BLACKWELL, 394–402 p.

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