Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2013-04-01 |
タイトル |
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タイトル |
Neuroanatomical correlates of attention-deficit-hyperactivity disorder accounting for comorbid oppositional defiant disorder and conduct disorder |
言語 |
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言語 |
eng |
DOI |
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関連識別子 |
https://doi.org/10.1111/j.1440-1819.2010.02102.x |
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関連名称 |
10.1111/j.1440-1819.2010.02102.x |
キーワード |
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主題 |
attention deficit hyperactivity disorder, brain, magnetic resonance imaging, voxel-based morphometry |
資源タイプ |
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資源 |
http://purl.org/coar/resource_type/c_6501 |
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タイプ |
journal article |
著者 |
Sasayama, Daimei
Hayashida, Ayako
Yamasue, Hidenori
Harada, Yuzuru
Kaneko, Tomoki
Kasai, Kiyoto
Washizuka, Shinsuke
Amano, Naoji
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信州大学研究者総覧へのリンク |
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氏名 |
Sasayama, Daimei |
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URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.uNkegpkh.html |
信州大学研究者総覧へのリンク |
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氏名 |
Harada, Yuzuru |
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URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.yFcCuUkh.html |
信州大学研究者総覧へのリンク |
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氏名 |
Kaneko, Tomoki |
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URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.WayFuakh.html |
信州大学研究者総覧へのリンク |
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氏名 |
Washizuka, Shinsuke |
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URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.uhnNuakh.html |
出版者 |
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出版者 |
WILEY-BLACKWELL |
引用 |
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内容記述 |
PSYCHIATRY AND CLINICAL NEUROSCIENCES. 64(4):394-402 (2010) |
書誌情報 |
PSYCHIATRY AND CLINICAL NEUROSCIENCES
巻 64,
号 4,
p. 394-402,
発行日 2010
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抄録 |
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内容記述 |
Aim: An increasing number of neuroimaging studies have been conducted to uncover the pathophysiology of attention-deficit-hyperactivity disorder (ADHD). The findings are inconsistent, however, at least partially due to methodological differences. In the present study voxel-based morphometry (VBM) was used to evaluate brain morphology in ADHD subjects after taking into account the confounding effect of oppositional defiant disorder (ODD) and conduct disorder (CD) comorbidity. Methods: Eighteen children with ADHD and 17 age-and gender-matched typically developing subjects underwent high-spatial resolution magnetic resonance imaging. The regional gray matter volume differences between the children with ADHD and controls were examined with and without accounting for comorbid ODD and CD in a voxel-by-voxel manner throughout the entire brain. Results: The VBM indicated significantly smaller regional gray matter volume in regions including the bilateral temporal polar and occipital cortices and the left amygdala in subjects with ADHD compared with controls. Significantly smaller regional gray matter volumes were demonstrated in more extensive regions including the bilateral temporal polar cortices, bilateral amygdala, right occipital cortex, right superior temporal sulcus, and left middle frontal gyrus after controlling for the confounding effect of comorbid ODD and CD. Conclusion: Morphological abnormalities in ADHD were seen not only in the regions associated with executive functioning but also in the regions associated with social cognition. When the effect of comorbid CD and ODD was taken into account, there were more extensive regions with significantly smaller volume in ADHD compared to controls. |
資源タイプ(コンテンツの種類) |
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内容記述 |
Article |
ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
1323-1316 |
書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA11040669 |
PubMed |
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関連識別子 |
https://pubmed.ncbi.nlm.nih.gov/20546170 |
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関連名称 |
20546170 |
権利 |
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権利情報 |
The definitive version is available at www.wileyonlinelibrary.com |
出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
WoS |
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URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000280355800007 |