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We investigated the validity of the Total Dysphagia Risk Score (TDRS) as a predictive measure for this morbidity. Materials and methods: Forty-seven patients with head and neck cancers who underwent definitive chemoradiotherapy between December 1998 and March 2006 were reviewed retrospectively. Median age was 63 years (range, 16-81). Almost all patients underwent platinum-based concomitant chemoradiotherapy. Factors of the TDRS were as follows: T-classification, neck irradiation, weight loss, primary tumour site and treatment modality. Patients were classified into three risk groups according to the TDRS. Results: Swallowing dysfunction was observed in 27 patients (57%) as RTOG grade 2 or higher acute morbidity. This classification was significantly associated with grade 2 or higher acute swallowing dysfunction (P \u003c 0.001). In ROC (receiver operator characteristic) analysis, the cut-off value of TDRS was set at 18 (sensitivity = 0.81; specificity = 0.85). 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  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

Validation of the Total Dysphagia Risk Score (TDRS) as a predictive measure for acute swallowing dysfunction induced by chemoradiotherapy for head and neck cancers

http://hdl.handle.net/10091/16250
1f66acd6-13ab-4933-8292-b72b7f990b57
名前 / ファイル ライセンス アクション
Validation_Total_Dysphagia_Risk_Score_TDRS.pdf Validation_Total_Dysphagia_Risk_Score_TDRS.pdf (233.6 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2013-02-13
タイトル
言語 en
タイトル Validation of the Total Dysphagia Risk Score (TDRS) as a predictive measure for acute swallowing dysfunction induced by chemoradiotherapy for head and neck cancers
言語
言語 eng
キーワード
主題Scheme Other
主題 Total Dysphagia Risk Score
キーワード
主題Scheme Other
主題 Chemoradiotherapy
キーワード
主題Scheme Other
主題 Head and neck cancer
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Koiwai, Keiichiro

× Koiwai, Keiichiro

WEKO 7258

en Koiwai, Keiichiro

Search repository
Shikama, Naoto

× Shikama, Naoto

WEKO 7259

en Shikama, Naoto

Search repository
Sasaki, Shigeru

× Sasaki, Shigeru

WEKO 7260

en Sasaki, Shigeru

Search repository
Shinoda, Atsunori

× Shinoda, Atsunori

WEKO 7261

en Shinoda, Atsunori

Search repository
Kadoya, Masumi

× Kadoya, Masumi

WEKO 7262

en Kadoya, Masumi

Search repository
信州大学研究者総覧へのリンク
氏名 Koiwai, Keiichiro
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.gCkCgUkh.html
出版者
出版者 ELSEVIER IRELAND LTD
引用
内容記述タイプ Other
内容記述 RADIOTHERAPY AND ONCOLOGY. 97(1):132-135 (2010)
書誌情報 RADIOTHERAPY AND ONCOLOGY

巻 97, 号 1, p. 132-135, 発行日 2010-10
抄録
内容記述タイプ Abstract
内容記述 Background and purpose: Methods for predicting acute swallowing dysfunction in patients with head and neck cancers undergoing definitive chemoradiotherapy have not been established. We investigated the validity of the Total Dysphagia Risk Score (TDRS) as a predictive measure for this morbidity. Materials and methods: Forty-seven patients with head and neck cancers who underwent definitive chemoradiotherapy between December 1998 and March 2006 were reviewed retrospectively. Median age was 63 years (range, 16-81). Almost all patients underwent platinum-based concomitant chemoradiotherapy. Factors of the TDRS were as follows: T-classification, neck irradiation, weight loss, primary tumour site and treatment modality. Patients were classified into three risk groups according to the TDRS. Results: Swallowing dysfunction was observed in 27 patients (57%) as RTOG grade 2 or higher acute morbidity. This classification was significantly associated with grade 2 or higher acute swallowing dysfunction (P < 0.001). In ROC (receiver operator characteristic) analysis, the cut-off value of TDRS was set at 18 (sensitivity = 0.81; specificity = 0.85). Prediction of severe (grade >= 3) acute swallowing dysfunction was similarly obtained. Conclusion: The TDRS is a useful tool to predict acute swallowing dysfunction induced by chemoradiotherapy for head and neck cancers.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 0167-8140
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA10476884
PubMed
関連識別子
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/20817288
関連名称
関連名称 20817288
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.radonc.2010.08.006
関連名称
関連名称 10.1016/j.radonc.2010.08.006
権利
権利情報 Copyright© 2010 Elsevier Ireland Ltd.
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000283685400024
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