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  1. 050 医学部, 大学院医学系研究科 (Faculty&Graduate School of Medicine)
  2. 0501 学術論文 (Journal Articles)

Association of IL28B gene polymorphism with development of hepatocellular carcinoma in Japanese patients with chronic hepatitis C virus infection

http://hdl.handle.net/10091/16243
a6a39449-2c57-467f-ac7c-d4dd2518389e
プレビュー
名前 / ファイル ライセンス Actions
Association_IL28B_Gene_Polymorphism_Development_Hepatocellular_Carcinoma.pdf Association_IL28B_Gene_Polymorphism_Development_Hepatocellular_Carcinoma.pdf (155.3 kB)
item type 学術雑誌論文 / Journal Article(1)
公開日 2013-02-13
タイトル
タイトル Association of IL28B gene polymorphism with development of hepatocellular carcinoma in Japanese patients with chronic hepatitis C virus infection
言語
言語 eng
キーワード
主題 IL28B
キーワード
主題 SNP
キーワード
主題 HCC
キーワード
主題 HCV
キーワード
主題 Cirrhosis
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Joshita, Satoru

× Joshita, Satoru

WEKO 7320

Joshita, Satoru

Search repository
Umemura, Takeji

× Umemura, Takeji

WEKO 7321

Umemura, Takeji

Search repository
Katsuyama, Yoshihiko

× Katsuyama, Yoshihiko

WEKO 7322

Katsuyama, Yoshihiko

Search repository
Ichikawa, Yuki

× Ichikawa, Yuki

WEKO 7323

Ichikawa, Yuki

Search repository
Kimura, Takefumi

× Kimura, Takefumi

WEKO 7324

Kimura, Takefumi

Search repository
Morita, Susumu

× Morita, Susumu

WEKO 7325

Morita, Susumu

Search repository
Kamijo, Atsushi

× Kamijo, Atsushi

WEKO 7326

Kamijo, Atsushi

Search repository
Komatsu, Michiharu

× Komatsu, Michiharu

WEKO 7327

Komatsu, Michiharu

Search repository
Ichijo, Tetsuya

× Ichijo, Tetsuya

WEKO 7328

Ichijo, Tetsuya

Search repository
Matsumoto, Akihiro

× Matsumoto, Akihiro

WEKO 7329

Matsumoto, Akihiro

Search repository
Yoshizawa, Kaname

× Yoshizawa, Kaname

WEKO 7330

Yoshizawa, Kaname

Search repository
Kamijo, Nozomi

× Kamijo, Nozomi

WEKO 7331

Kamijo, Nozomi

Search repository
Ota, Masao

× Ota, Masao

WEKO 7332

Ota, Masao

Search repository
Tanaka, Eiji

× Tanaka, Eiji

WEKO 7333

Tanaka, Eiji

Search repository
信州大学研究者総覧へのリンク
Joshita, Satoru
http://soar-rd.shinshu-u.ac.jp/profile/ja.PeLNbVym.html
信州大学研究者総覧へのリンク
Umemura, Takeji
http://soar-rd.shinshu-u.ac.jp/profile/ja.ymSpgpkh.html
信州大学研究者総覧へのリンク
Ota, Masao
http://soar-rd.shinshu-u.ac.jp/profile/ja.ZefVOFkh.html
信州大学研究者総覧へのリンク
Tanaka, Eiji
http://soar-rd.shinshu-u.ac.jp/profile/ja.HFDCHekh.html
出版者
出版者 ELSEVIER SCIENCE INC
引用
内容記述タイプ Other
内容記述 HUMAN IMMUNOLOGY. 73(3):298-300 (2012)
書誌情報 HUMAN IMMUNOLOGY

巻 73, 号 3, p. 298-300, 発行日 2012-03
抄録
内容記述タイプ Abstract
内容記述 IL28B single nucleotide polymorphisms (SNPs) are associated with spontaneous and treatment-induced elimination of hepatitis C virus (HCV). To assess whether the IL28B rs8099917 SNP also affects the progression of chronic HCV infection, we genotyped 511 Japanese HCV patients, including 69 with hepatocellular carcinoma (HCC). The T/T genotype of rs8099917 was not associated with the development of HCC (p = 0.623), although stepwise logistic regression analysis showed that liver cirrhosis, age greater than 68 years, and serum albumin <4.2 mg/dl were associated with HCC onset. It appears that the IL28B SNP does not directly influence hepatocarcinogenesis in chronic HCV infection.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ ISSN
収録物識別子 0198-8859
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00214087
PubMed
関連識別子
識別子タイプ PMID
関連識別子 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=22245236
関連名称
関連名称 22245236
DOI
関連識別子
識別子タイプ DOI
関連識別子 http://dx.doi.org/10.1016/j.humimm.2011.12.021
関連名称
関連名称 10.1016/j.humimm.2011.12.021
権利
権利情報 Copyright© 2012 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc.
著者版フラグ
値 author
WoS
Web of Science
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000300964400014
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