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Hereditary Pancreatitis Model WBN/Kob Rat Strain Has a Unique Haplotype in the Pdwk1 Region on Chromosome 7
http://hdl.handle.net/10091/13263
http://hdl.handle.net/10091/132631126f25f-fbb0-4236-a32e-943db73c57f1
| 名前 / ファイル | ライセンス | アクション |
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Hereditary_Pancreatitis_Model_WBNKob_Rat_Strain.pdf (428.0 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||
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| 公開日 | 2011-10-11 | |||||||||||||||
| タイトル | ||||||||||||||||
| タイトル | Hereditary Pancreatitis Model WBN/Kob Rat Strain Has a Unique Haplotype in the Pdwk1 Region on Chromosome 7 | |||||||||||||||
| 言語 | ||||||||||||||||
| 言語 | eng | |||||||||||||||
| DOI | ||||||||||||||||
| 関連識別子 | https://doi.org/10.1538/expanim.58.409 | |||||||||||||||
| 関連名称 | 10.1538/expanim.58.409 | |||||||||||||||
| キーワード | ||||||||||||||||
| 主題 | gene polymorphism, pancreatitis, WBN/Kob | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||
| タイプ | journal article | |||||||||||||||
| 著者 |
Mori, Masayuki
× Mori, Masayuki
× Fu, Xiaoying
× Chen, Lei
× Zhang, Guohong
× Higuchi, Keiichi
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| 信州大学研究者総覧へのリンク | ||||||||||||||||
| 氏名 | Mori, Masayuki | |||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.OpSCZafV.html | |||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||
| 氏名 | Higuchi, Keiichi | |||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.gCfUPmAh.html | |||||||||||||||
| 出版者 | ||||||||||||||||
| 出版者 | Japanese Association for Laboratory Animal Science | |||||||||||||||
| 引用 | ||||||||||||||||
| 内容記述 | EXPERIMENTAL ANIMALS. 58(4):409-413 (2009) | |||||||||||||||
| 書誌情報 |
EXPERIMENTAL ANIMALS 巻 58, 号 4, p. 409-413, 発行日 2009-07 |
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| 抄録 | ||||||||||||||||
| 内容記述 | The WBN/Kob rat strain is a hereditary animal model of chronic pancreatitis and diabetes mellitus. The major WBN/Kob loci for pancreatitis (Pdwk1 and Pdwk2) are located on chromosomes 7 and X, respectively. In this study, polymorphisms were sought for candidate genes in the Pdwk1 and Pdwk2 regions. Nucleotide polymorphisms were found in 14 candidate genes examined in the Pdwk1 region. These polymorphisms were not associated with functional changes, and hence were unlikely to be a cause of pancreatitis. Seven nucleotide polymorphisms in three candidate genes, Rac2, Grap2, and Xpnpep3, located within a 3.3-Mb region were not found in 14 other inbred rat strains. These results suggest that WBN/Kob has a unique haplotype block in the chromosomal region containing Pdwk1. | |||||||||||||||
| 資源タイプ（コンテンツの種類） | ||||||||||||||||
| ISSN | ||||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||||
| 収録物識別子 | 1341-1357 | |||||||||||||||
| 書誌レコードID | ||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||
| 収録物識別子 | AA11032321 | |||||||||||||||
| PubMed | ||||||||||||||||
| 識別子タイプ | PMID | |||||||||||||||
| 関連識別子 | https://pubmed.ncbi.nlm.nih.gov/19654439 | |||||||||||||||
| 関連名称 | 19654439 | |||||||||||||||
| 出版タイプ | ||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||
| WoS | ||||||||||||||||
| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000268442400010 | |||||||||||||||
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Cite as
Mori, Masayuki, Fu, Xiaoying, Chen, Lei, Zhang, Guohong, Higuchi, Keiichi, 2009, Hereditary Pancreatitis Model WBN/Kob Rat Strain Has a Unique Haplotype in the Pdwk1 Region on Chromosome 7: Japanese Association for Laboratory Animal Science, 409–413 p.
