| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2011-01-19 |
| タイトル |
|
|
タイトル |
Nonalcoholic fatty liver disease in Japanese junior high school students: its prevalence and relationship to lifestyle habits |
| 言語 |
|
|
言語 |
eng |
| DOI |
|
|
|
関連識別子 |
https://doi.org/10.1007/s00535-009-0198-4 |
|
|
関連名称 |
10.1007/s00535-009-0198-4 |
| キーワード |
|
|
主題 |
Obesity, ALT, Physical activity, Skipping breakfast, Nonalcoholic steatohepatitis |
| 資源タイプ |
|
|
資源 |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 著者 |
Tsuruta, Goro
Tanaka, Naoki
Hongo, Minoru
Komatsu, Michiharu
Horiuchi, Akira
Hamamoto, Kaeko
Iguchi, Chieko
Nakayama, Yoshiko
Umemura, Takeji
Ichijo, Tetsuya
Matsumoto, Akihiro
Yoshizawa, Kaname
Aoyama, Toshifumi
Tanaka, Eiji
|
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Umemura, Takeji |
|
URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.ymSpgpkh.html |
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Tanaka, Eiji |
|
URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.HFDCHekh.html |
| 出版者 |
|
|
出版者 |
SPRINGER TOKYO |
| 引用 |
|
|
内容記述 |
JOURNAL OF GASTROENTEROLOGY. 45(6):666-672 (2010) |
| 書誌情報 |
JOURNAL OF GASTROENTEROLOGY
巻 45,
号 6,
p. 666-672,
発行日 2010-06
|
| 内容記述 |
|
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内容記述タイプ |
Other |
|
内容記述 |
The original publication is available at www.springerlink.com |
| 抄録 |
|
|
内容記述 |
Despite the increase in nonalcoholic fatty liver disease (NAFLD) in Japanese adults, its prevalence in adolescents remains unclear. This prompted us to evaluate the incidence and clinical characteristics of NAFLD among junior high school students. A population-based cross-sectional study was conducted among students in a single junior high school in Nagano prefecture. Serum alanine aminotransferase (ALT) and gamma-glutamyltransferase (gamma GT) measurements and abdominal ultrasonography were performed in 249 and 288 students in 2004 and 2007, respectively. In the latter survey, student lifestyle habits were also assessed, using questionnaires. The prevalence of NAFLD was 4.4% and 4.5% in 2004 and 2007, respectively, which was lower than that of obesity (10.0% and 5.9%). Body mass index and ALT and gamma GT levels increased significantly with hepatic steatosis severity. Multivariate logistic regression analysis demonstrated that the presence of obesity and an ALT level of 30 U/L or more were independent predictors of NAFLD (odds ratio 16.9, P < 0.001 and odds ratio 16.6, P = 0.001, respectively). The ratios of students commuting to and from school by car and not doing sports outside of school were higher in NAFLD students compared with non-NAFLD ones. Such tendencies were observed independently of the presence of obesity. Additionally, one obese student with severe steatosis and liver dysfunction was diagnosed as having nonalcoholic steatohepatitis (NASH). Approximately 4% of junior high school students had NAFLD that was primarily associated with obesity and reduced daily physical activity. Serum ALT measurement during school check-ups is recommended for the early detection of young adolescent NAFLD/NASH. |
| 資源タイプ（コンテンツの種類） |
|
| ISSN |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0944-1174 |
| 書誌レコードID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA10988015 |
| PubMed |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
https://pubmed.ncbi.nlm.nih.gov/20084525 |
|
|
関連名称 |
20084525 |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| WoS |
|
|
URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000278738300011 |
Nonalcoholic_fatty_liver_disease.pdf (827.3 kB)
