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In this study, these markers were investigated in the left atria (LA) of patients with paroxysmal atrial fibrillation (pAF) in the non-paroxysmal period. Methods and Results: Patients with pAF (n=10) and chronic AF (cAF) (n=10) were enrol led. TAT, PIC, and PF4 levels were determined in blood samples obtained from the LA of AF patients before radiolrequency catheter ablation. TAT levels were high in both pAF and cAF patients. PF4 levels were slightly elevated in both groups. but there was no significant difference between the groups. On the other hand, PIC levels in both groups were almost within normal limits, again with no significant difference between groups. Conclusions: Coagulation activity is elevated in the LA of patients with pAF, even in the non-paroxysmal period, so these patients are at high risk of thromboembolism and anticoagulant therapy is indicated. 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  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

Coagulation Activity is Increased in the Left Atria of Patients With Paroxysmal Atrial Fibrillation During the Non-Paroxysmal Period - Comparison With Chronic Atrial Fibrillation -

http://hdl.handle.net/10091/10810
http://hdl.handle.net/10091/10810
0b8e7c43-0537-4ab8-a2ed-a4fddddb8bb5
名前 / ファイル ライセンス アクション
Coagulation_Activity_Increased_Left_Atria.pdf Coagulation_Activity_Increased_Left_Atria.pdf (175.0 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2010-12-01
タイトル
言語 en
タイトル Coagulation Activity is Increased in the Left Atria of Patients With Paroxysmal Atrial Fibrillation During the Non-Paroxysmal Period - Comparison With Chronic Atrial Fibrillation -
言語
言語 eng
キーワード
主題Scheme Other
主題 Coagulation
キーワード
主題Scheme Other
主題 Left atrium
キーワード
主題Scheme Other
主題 Paroxysmal atrial fibrillation
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Motoki, Hirohiko

× Motoki, Hirohiko

WEKO 7918

en Motoki, Hirohiko

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Tomita, Takeshi

× Tomita, Takeshi

WEKO 7919

en Tomita, Takeshi

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Aizawa, Kazunori

× Aizawa, Kazunori

WEKO 7920

en Aizawa, Kazunori

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Kasai, Hiroki

× Kasai, Hiroki

WEKO 7921

en Kasai, Hiroki

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Izawa, Atsushi

× Izawa, Atsushi

WEKO 7922

en Izawa, Atsushi

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Kumazaki, Setsuo

× Kumazaki, Setsuo

WEKO 7923

en Kumazaki, Setsuo

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Tsutsui, Hiroshi

× Tsutsui, Hiroshi

WEKO 7924

en Tsutsui, Hiroshi

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Koyama, Jun

× Koyama, Jun

WEKO 7925

en Koyama, Jun

Search repository
Ikeda, Uichi

× Ikeda, Uichi

WEKO 7926

en Ikeda, Uichi

Search repository
信州大学研究者総覧へのリンク
氏名 Motoki, Hirohiko
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.ymfFgpkh.html
信州大学研究者総覧へのリンク
氏名 Izawa, Atsushi
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.yNnVgpkh.html
出版者
出版者 JAPANESE CIRCULATION SOC
引用
内容記述タイプ Other
内容記述 CIRCULATION JOURNAL. 73(8):1403-1407 (2009)
書誌情報 CIRCULATION JOURNAL. 73(8):1403-1407 (2009)

巻 73, 号 8, p. 1403-1407, 発行日 2009-08
抄録
内容記述タイプ Abstract
内容記述 Background: Evaluation of plasma markers of thrombin activity (thrombin-antithrombin HI complex: TAT), active fibrinolysis (plasmin-a 2-plasmin inhibitor complex: PIC), and platelet activity (platelet factor 4: PF4) is useful for identifying patients with various cardiovascular disorders who are at high risk of thrornboembolism. In this study, these markers were investigated in the left atria (LA) of patients with paroxysmal atrial fibrillation (pAF) in the non-paroxysmal period. Methods and Results: Patients with pAF (n=10) and chronic AF (cAF) (n=10) were enrol led. TAT, PIC, and PF4 levels were determined in blood samples obtained from the LA of AF patients before radiolrequency catheter ablation. TAT levels were high in both pAF and cAF patients. PF4 levels were slightly elevated in both groups. but there was no significant difference between the groups. On the other hand, PIC levels in both groups were almost within normal limits, again with no significant difference between groups. Conclusions: Coagulation activity is elevated in the LA of patients with pAF, even in the non-paroxysmal period, so these patients are at high risk of thromboembolism and anticoagulant therapy is indicated.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 1346-9843
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA11591968
PubMed
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/19521017
関連名称 19521017
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1253/circj.CJ-09-0008
関連名称 10.1253/circj.CJ-09-0008
権利
権利情報 Copyright (c) 2009 THE JAPANESE CIRCULATION SOCIETY
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000268433600011
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