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Sixteen of 130 normal healthy males and 2 of 10 normal females without a history of pregnancy (none had ever been transfused) possessed HLA class I antibodies. In SLE, male, but not female patients, showed a significant increase in the frequency of the antibodies compared with the corresponding controls. The antibodies did not appear to be involved in the development of SLE because of no substantial relationship to the incidence of cytopenia or SLE disease activity index score. Each individual had 1-31 types of HLA class I antibodies. Interestingly, HLA class I antibodies did not correspond to the individual\u0027s own HLA antigens. Eight of 32 types of HLA class I antigens detected were rare in the Japanese population. These results suggest that an IgG component of naturally occurring HLA class I antibodies exists in human serum and that these antibodies are not antibodies against self-antigens."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Zhou, B", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8349", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Saito, S", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8350", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakazawa, Y", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8351", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kobayashi, N", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8352", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsuda, M", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8353", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsumoto, Y", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8354", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hosoyama, T", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8355", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Koike, K", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8356", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "バインダ1.pdf", "filesize": [{"value": "445.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 445400.0, "url": {"label": "バインダ1.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/3973/files/バインダ1.pdf"}, "version_id": "a80f18d2-fd72-46b6-bec7-4940ed5956f3"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Existence of an immunoglobulin G component of naturally occurring HLA class I antibodies that are not directed against self-antigens in human serum", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Existence of an immunoglobulin G component of naturally occurring HLA class I antibodies that are not directed against self-antigens in human serum", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["462"], "permalink_uri": "http://hdl.handle.net/10091/1133", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2008-09-03"}, "publish_date": "2008-09-03", "publish_status": "0", "recid": "3973", "relation": {}, "relation_version_is_last": true, "title": ["Existence of an immunoglobulin G component of naturally occurring HLA class I antibodies that are not directed against self-antigens in human serum"], "weko_shared_id": -1}
Existence of an immunoglobulin G component of naturally occurring HLA class I antibodies that are not directed against self-antigens in human serum
http://hdl.handle.net/10091/1133
http://hdl.handle.net/10091/113396f95c1b-0f78-4b6f-8b0c-53f31d770dca
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-09-03 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Existence of an immunoglobulin G component of naturally occurring HLA class I antibodies that are not directed against self-antigens in human serum | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Zhou, B
× Zhou, B× Saito, S× Nakazawa, Y× Kobayashi, N× Matsuda, M× Matsumoto, Y× Hosoyama, T× Koike, K |
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信州大学研究者総覧へのリンク | ||||||
氏名 | Nakazawa, Y | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.yCSFuNkh.html | |||||
出版者 | ||||||
出版者 | BLACKWELL PUBLISHING | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | TISSUE ANTIGENS. 72(2):98-104(2008) | |||||
書誌情報 |
TISSUE ANTIGENS 巻 72, 号 2, p. 98-104, 発行日 2008-08 |
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内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Author Posting. c The Authors 2008 This is the author's version of the work. It is posted here for personal use, not for redistribution. The definitive version was published in Tissue Antigens, 72(2):98-104. https://doi.org/10.1111/j.1399-0039.2008.01074.x | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0001-2815 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00863818 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1111/j.1399-0039.2008.01074.x | |||||
関連名称 | 10.1111/j.1399-0039.2008.01074.x | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
WoS | ||||||
表示名 | Web of Science | |||||
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