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In the elderly group, nine (45%) patients had accumulations of lymphocytes, indicating an atrophied thymus with loss of the basic structure. The elderly MG patients with atrophied thymic tissues had higher titres of anti-AChR antibody (59.6 +/- 81.0 nmol/L) than those with adipose infiltration of the thymus alone (20.1 +/- 20.9 nmol/L). In immunohistochemical studies using image analysis, both young patients and elderly patients with atrophied thymic tissues were found to have significantly higher levels of CD20 than age-matched controls (p \u003c 0.005). Atrophied thymic tissues, often seen immunohistochemically in young MG patients, may also be found in elderly patients, particularly in those with high titres of the anti-AChR antibody, even though adipose infiltration is marked in these patients. (c) 2006 Elsevier Ltd. All rights reserved."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ishii, W", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8634", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsuda, M", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8635", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hanyuda, M", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8636", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Momose, M", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8637", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakayama, J", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8638", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ehara, T", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8639", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ikeda, S", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8640", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "MG text, new, JCN.pdf", "filesize": [{"value": "66.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 66300.0, "url": {"label": "MG text, new, JCN.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/4018/files/MG text, new, JCN.pdf"}, "version_id": "945bfcdb-94da-4de4-9d77-477ac7d807b8"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Comparison of the histological and immunohistochemical features of the thymus in young- and elderly-onset myasthenia gravis without thymoma", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Comparison of the histological and immunohistochemical features of the thymus in young- and elderly-onset myasthenia gravis without thymoma", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["462"], "permalink_uri": "http://hdl.handle.net/10091/620", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2007-11-22"}, "publish_date": "2007-11-22", "publish_status": "0", "recid": "4018", "relation": {}, "relation_version_is_last": true, "title": ["Comparison of the histological and immunohistochemical features of the thymus in young- and elderly-onset myasthenia gravis without thymoma"], "weko_shared_id": -1}
Comparison of the histological and immunohistochemical features of the thymus in young- and elderly-onset myasthenia gravis without thymoma
http://hdl.handle.net/10091/620
http://hdl.handle.net/10091/6207711c003-5295-4798-b241-02301c6ea667
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2007-11-22 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Comparison of the histological and immunohistochemical features of the thymus in young- and elderly-onset myasthenia gravis without thymoma | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Ishii, W
× Ishii, W× Matsuda, M× Hanyuda, M× Momose, M× Nakayama, J× Ehara, T× Ikeda, S |
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信州大学研究者総覧へのリンク | ||||||
氏名 | Nakayama, J | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.HCApHFkh.html | |||||
出版者 | ||||||
出版者 | CHURCHILL LIVINGSTONE | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | JOURNAL OF CLINICAL NEUROSCIENCE. 14(2): 110-115 (2007) | |||||
書誌情報 |
JOURNAL OF CLINICAL NEUROSCIENCE 巻 14, 号 2, p. 110-115, 発行日 2007-02 |
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資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0967-5868 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10958444 | |||||
他の資源との関係:URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.elsevier.com/wps/find/journaldescription.cws_home/623056/description | |||||
関連名称 | http://www.elsevier.com/wps/find/journaldescription.cws_home/623056/description | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.jocn.2005.11.048 | |||||
関連名称 | 10.1016/j.jocn.2005.11.048 | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000243389400003 |