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We aimed to test this possibility and to isolate factors that may indicate NASH. Methods: First, 53 Japanese patients diagnosed as having cryptogenic chronic hepatitis by laboratory examination and US were enrolled. These patients were histologically divided into NASH and non-NASH groups, and their clinical features were compared. Second, the diagnostic accuracy of predictors of NASH was examined prospectively. Results: Fifteen patients (28%) were histologically diagnosed as having NASH with mild steatosis. Multivariable analysis revealed that body mass index (BMI) and serum ferritin level were independent predictors of NASH. The best cutoff values to detect NASH were assessed by using receiver-operating characteristic curves: BMI \u003e 25.2 kg/m(2) and serum ferritin level \u003e 142 ng/ml. When both markers were concomitantly negative, the negative predictive value to detect NASH was 100%. Conclusions: In cases of mild steatosis, US is not a perfect tool for the accurate diagnosis of NASH. BMI and serum ferritin level are useful discriminators of NASH from cryptogenic chronic hepatitis, and might be helpful markers for diagnosing NASH more accurately in Japanese patients."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Tanaka, N", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8825", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka, E", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8826", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sheena, Y", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8827", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Komatsu, M", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8828", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okiyama, W", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8829", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Misawa, N", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8830", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Muto, H", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8831", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Umemura, T", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8832", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ichijo, T", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8833", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsumoto, A", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8834", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshizawa, K", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8835", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Horiuchi, A", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8836", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kiyosawa, K", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8837", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Predictors of NASH with mild steatosis.pdf", "filesize": [{"value": "165.6 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 165600.0, "url": {"label": "Predictors of NASH with mild steatosis.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/4046/files/Predictors of NASH with mild steatosis.pdf"}, "version_id": "e352efa1-e7bd-4135-b5a7-7a8d8cde5d61"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["462"], "permalink_uri": "http://hdl.handle.net/10091/226", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2007-05-15"}, "publish_date": "2007-05-15", "publish_status": "0", "recid": "4046", "relation": {}, "relation_version_is_last": true, "title": ["Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population"], "weko_shared_id": -1}
Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population
http://hdl.handle.net/10091/226
http://hdl.handle.net/10091/2264592f6a1-a563-4111-84b8-0840af655f21
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2007-05-15 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Tanaka, N
× Tanaka, N× Tanaka, E× Sheena, Y× Komatsu, M× Okiyama, W× Misawa, N× Muto, H× Umemura, T× Ichijo, T× Matsumoto, A× Yoshizawa, K× Horiuchi, A× Kiyosawa, K |
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信州大学研究者総覧へのリンク | ||||||
氏名 | Tanaka, E | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.HFDCHekh.html | |||||
出版者 | ||||||
出版者 | BLACKWELL PUBLISHING | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | LIVER INTERNATIONAL. 26(8): 956-963 (2006) | |||||
書誌情報 |
LIVER INTERNATIONAL 巻 26, 号 8, p. 956-963, 発行日 2006-10 |
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内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | The definitive version is available at www.blackwell-synergy.com. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 1478-3223 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11817539 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1111/j.1478-3231.2006.01338.x | |||||
関連名称 | 10.1111/j.1478-3231.2006.01338.x | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000240319300010 |