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We aimed to test this possibility and to isolate factors that may indicate NASH. Methods: First, 53 Japanese patients diagnosed as having cryptogenic chronic hepatitis by laboratory examination and US were enrolled. These patients were histologically divided into NASH and non-NASH groups, and their clinical features were compared. Second, the diagnostic accuracy of predictors of NASH was examined prospectively. Results: Fifteen patients (28%) were histologically diagnosed as having NASH with mild steatosis. Multivariable analysis revealed that body mass index (BMI) and serum ferritin level were independent predictors of NASH. The best cutoff values to detect NASH were assessed by using receiver-operating characteristic curves: BMI \u003e 25.2 kg/m(2) and serum ferritin level \u003e 142 ng/ml. When both markers were concomitantly negative, the negative predictive value to detect NASH was 100%. Conclusions: In cases of mild steatosis, US is not a perfect tool for the accurate diagnosis of NASH. BMI and serum ferritin level are useful discriminators of NASH from cryptogenic chronic hepatitis, and might be helpful markers for diagnosing NASH more accurately in Japanese patients."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Tanaka,  N", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8825", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka,  E", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8826", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sheena,  Y", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8827", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Komatsu,  M", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8828", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okiyama,  W", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8829", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Misawa,  N", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8830", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Muto,  H", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8831", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Umemura,  T", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8832", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ichijo,  T", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8833", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsumoto,  A", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8834", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshizawa,  K", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8835", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Horiuchi,  A", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8836", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kiyosawa,  K", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8837", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Predictors of NASH with mild steatosis.pdf", "filesize": [{"value": "165.6 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 165600.0, "url": {"label": "Predictors of NASH with mild steatosis.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/4046/files/Predictors of NASH with mild steatosis.pdf"}, "version_id": "e352efa1-e7bd-4135-b5a7-7a8d8cde5d61"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["462"], "permalink_uri": "http://hdl.handle.net/10091/226", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2007-05-15"}, "publish_date": "2007-05-15", "publish_status": "0", "recid": "4046", "relation": {}, "relation_version_is_last": true, "title": ["Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population"], "weko_shared_id": -1}
  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population

http://hdl.handle.net/10091/226
http://hdl.handle.net/10091/226
4592f6a1-a563-4111-84b8-0840af655f21
名前 / ファイル ライセンス アクション
Predictors Predictors of NASH with mild steatosis.pdf (165.6 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2007-05-15
タイトル
言語 en
タイトル Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Tanaka, N

× Tanaka, N

WEKO 8825

en Tanaka, N

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Tanaka, E

× Tanaka, E

WEKO 8826

en Tanaka, E

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Sheena, Y

× Sheena, Y

WEKO 8827

en Sheena, Y

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Komatsu, M

× Komatsu, M

WEKO 8828

en Komatsu, M

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Okiyama, W

× Okiyama, W

WEKO 8829

en Okiyama, W

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Misawa, N

× Misawa, N

WEKO 8830

en Misawa, N

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Muto, H

× Muto, H

WEKO 8831

en Muto, H

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Umemura, T

× Umemura, T

WEKO 8832

en Umemura, T

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Ichijo, T

× Ichijo, T

WEKO 8833

en Ichijo, T

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Matsumoto, A

× Matsumoto, A

WEKO 8834

en Matsumoto, A

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Yoshizawa, K

× Yoshizawa, K

WEKO 8835

en Yoshizawa, K

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Horiuchi, A

× Horiuchi, A

WEKO 8836

en Horiuchi, A

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Kiyosawa, K

× Kiyosawa, K

WEKO 8837

en Kiyosawa, K

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信州大学研究者総覧へのリンク
氏名 Tanaka, E
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.HFDCHekh.html
出版者
出版者 BLACKWELL PUBLISHING
引用
内容記述タイプ Other
内容記述 LIVER INTERNATIONAL. 26(8): 956-963 (2006)
書誌情報 LIVER INTERNATIONAL

巻 26, 号 8, p. 956-963, 発行日 2006-10
内容記述
内容記述タイプ Other
内容記述 The definitive version is available at www.blackwell-synergy.com.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 1478-3223
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA11817539
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1111/j.1478-3231.2006.01338.x
関連名称 10.1111/j.1478-3231.2006.01338.x
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000240319300010
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