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Of the 2795 patients who satisfied criteria for analysis after treatment from any of 30 medical institutions, 657 had received lamivudine and the remaining 2138 had not. A Cox regression model with liver biopsy as the starting point revealed seven factors related to HCC: lamivudine therapy, gender, family clustering of hepatitis B, age at liver biopsy, hepatic fibrosis stage, serum albumin level, and platelet count. In a matched case-controlled study, 377 patients in a lamivudine-treated group and 377 matched patients in a non-treated group were selected based on their propensity scores. The mean follow-up period was 2.7 years in the lamivudine group and 5.3 years in the control group. In the lamivudine group, HCC occurred in four patients (1.1 %) with an annual incidence rate of 0.4 %/(patient/year), whereas in the control group HCC occurred in 50 patients (13.3 %) for a rate of 2.5 %/(patient/year). 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  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

Efficacy of lamivudine for preventing hepatocellular carcinoma in chronic hepatitis B: A multicenter retrospective study of 2795 patients

http://hdl.handle.net/10091/222
702c594c-dea7-43fd-990e-02fbacdbadf9
名前 / ファイル ライセンス アクション
Lamivudine Lamivudine treatment suppresses the occurrence of HCC in chronic hepatitis B.pdf (168.5 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2007-05-14
タイトル
言語 en
タイトル Efficacy of lamivudine for preventing hepatocellular carcinoma in chronic hepatitis B: A multicenter retrospective study of 2795 patients
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Matsumoto, A

× Matsumoto, A

WEKO 8873

en Matsumoto, A

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Tanaka, E

× Tanaka, E

WEKO 8874

en Tanaka, E

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Rokuhara, A

× Rokuhara, A

WEKO 8875

en Rokuhara, A

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Kiyosawa, K

× Kiyosawa, K

WEKO 8876

en Kiyosawa, K

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Kumada, H

× Kumada, H

WEKO 8877

en Kumada, H

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Omata, M

× Omata, M

WEKO 8878

en Omata, M

Search repository
Okita, K

× Okita, K

WEKO 8879

en Okita, K

Search repository
Hayashi, N

× Hayashi, N

WEKO 8880

en Hayashi, N

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Okanoue, T

× Okanoue, T

WEKO 8881

en Okanoue, T

Search repository
Iino, S

× Iino, S

WEKO 8882

en Iino, S

Search repository
Tanikawa, K

× Tanikawa, K

WEKO 8883

en Tanikawa, K

Search repository
信州大学研究者総覧へのリンク
氏名 Tanaka, E
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.HFDCHekh.html
出版者
出版者 ELSEVIER IRELAND LTD
引用
内容記述タイプ Other
内容記述 HEPATOLOGY RESEARCH. 32(3): 173-184 (2005)
書誌情報 HEPATOLOGY RESEARCH

巻 32, 号 3, p. 173-184, 発行日 2005-07
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 1386-6346
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA11140867
他の資源との関係:URI
関連識別子
識別子タイプ URI
関連識別子 http://www.elsevier.com/wps/find/journaldescription.cws_home/524224/description#description
関連名称
関連名称 http://www.elsevier.com/wps/find/journaldescription.cws_home/524224/description#description
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.hepres.2005.02.006
関連名称
関連名称 10.1016/j.hepres.2005.02.006
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000231351700007
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