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Phase II Trial of Biweekly Paclitaxel and Gemcitabine as Second-Line Chemotherapy for Non-Small Cell Lung Cancer Previously Treated with Platinum-Based Chemotherapy
http://hdl.handle.net/10091/13507
http://hdl.handle.net/10091/13507b40fd3af-9740-4401-94e6-4cf68da8f057
| 名前 / ファイル | ライセンス | アクション |
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Shinshu_med59-6-02.pdf (231.9 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||||||||||
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| 公開日 | 2012-01-04 | |||||||||||||||||
| タイトル | ||||||||||||||||||
| タイトル | Phase II Trial of Biweekly Paclitaxel and Gemcitabine as Second-Line Chemotherapy for Non-Small Cell Lung Cancer Previously Treated with Platinum-Based Chemotherapy | |||||||||||||||||
| 言語 | ||||||||||||||||||
| 言語 | eng | |||||||||||||||||
| DOI | ||||||||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||||||||
| 関連識別子 | https://doi.org/10.11441/shinshumedj.59.411 | |||||||||||||||||
| 関連名称 | 10.11441/shinshumedj.59.411 | |||||||||||||||||
| キーワード | ||||||||||||||||||
| 主題 | second-line chemotherapy, platinum-resistant, non-small cell lung cancer, neurotoxicity | |||||||||||||||||
| 資源タイプ | ||||||||||||||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||
| タイプ | departmental bulletin paper | |||||||||||||||||
| 著者 |
KOBAYASHI, Takashi
× KOBAYASHI, Takashi
× KOIZUMI, Tomonobu
× YASUO, Masanori
× TSUSHIMA, Kenji
× YAMAMOTO, Hiroshi
× KUBO, Keishi
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| 信州大学研究者総覧へのリンク | ||||||||||||||||||
| 氏名 | KOIZUMI, Tomonobu | |||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.WakmHhkh.html | |||||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||||
| 氏名 | YASUO, Masanori | |||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.ypnegpkh.html | |||||||||||||||||
| 出版者 | ||||||||||||||||||
| 出版者 | 信州医学会 | |||||||||||||||||
| 引用 | ||||||||||||||||||
| 内容記述 | 信州医学雑誌 59(6): 411-418(2011) | |||||||||||||||||
| 書誌情報 |
信州医学雑誌 巻 59, 号 6, p. 411-418, 発行日 2011-12-10 |
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| 抄録 | ||||||||||||||||||
| 内容記述 | A phase II study was conducted to evaluate the feasibility and efficacy of biweekly administration of paclitaxel and gemcitabine in patients with non-small cell lung cancer (NSCLC) who had been treated previously with platinum-based chemotherapy. Paclitaxel (150 mg/m2) and gemcitabine (1,000 mg/m2) were administered biweekly for at least 4 cycles. Thirty-one patients with a median age of 64 years (39-75 years) were enrolled in this study(stage IIIB/IV :11/20,PS 0/1/2:13/16/2).Partial response was observed in 7 cases (23%), and stable disease was seen in 18 cases (58%).Median survival time was 8.8 months with a one-year survival rate of 41.9 %.Hematological toxicities were mild and neutropenia of grade 3 or above was observed in one patient (3%). Non-hematological toxicities were also mild, including neurotoxicity (3%). Biweekly paclitaxel and gemcitabine combination chemotherapy was effective and tolerated well as second-line therapy against NSCLC. | |||||||||||||||||
| 資源タイプ（コンテンツの種類） | ||||||||||||||||||
| ISSN | ||||||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||||||
| 収録物識別子 | 0037-3826 | |||||||||||||||||
| 書誌レコードID | ||||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||||
| 収録物識別子 | AN00120815 | |||||||||||||||||
| 出版タイプ | ||||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||
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KOBAYASHI, Takashi, KOIZUMI, Tomonobu, YASUO, Masanori, TSUSHIMA, Kenji, YAMAMOTO, Hiroshi, KUBO, Keishi, 2011, Phase II Trial of Biweekly Paclitaxel and Gemcitabine as Second-Line Chemotherapy for Non-Small Cell Lung Cancer Previously Treated with Platinum-Based Chemotherapy: 信州医学会, 411–418 p.
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