{"_buckets": {"deposit": "5a6f0c44-0eb6-434a-ac22-239383af6a12"}, "_deposit": {"id": "4145", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "4145"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00004145", "sets": []}, "author_link": ["9346", "9347", "9348", "9349", "9350", "9351"], "item_10_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2011-12-10", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "418", "bibliographicPageStart": "411", "bibliographicVolumeNumber": "59", "bibliographic_titles": [{"bibliographic_title": "\u4fe1\u5dde\u533b\u5b66\u96d1\u8a8c"}]}]}, "item_10_description_20": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "A phase II study was conducted to evaluate the feasibility and efficacy of biweekly administration of paclitaxel and gemcitabine in patients with non-small cell lung cancer (NSCLC) who had been treated previously with platinum-based chemotherapy. Paclitaxel (150 mg/m2) and gemcitabine (1,000 mg/m2) were administered biweekly for at least 4 cycles. Thirty-one patients with a median age of 64 years (39-75 years) were enrolled in this study(stage IIIB/IV :11/20,PS 0/1/2:13/16/2).Partial response was observed in 7 cases (23%), and stable disease was seen in 18 cases (58%).Median survival time was 8.8 months with a one-year survival rate of 41.9 %.Hematological toxicities were mild and neutropenia of grade 3 or above was observed in one patient (3%). Non-hematological toxicities were also mild, including neurotoxicity (3%). Biweekly paclitaxel and gemcitabine combination chemotherapy was effective and tolerated well as second-line therapy against NSCLC.", "subitem_description_type": "Abstract"}]}, "item_10_description_30": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7\uff08\u30b3\u30f3\u30c6\u30f3\u30c4\u306e\u7a2e\u985e\uff09", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_10_description_5": {"attribute_name": "\u5f15\u7528", "attribute_value_mlt": [{"subitem_description": "\u4fe1\u5dde\u533b\u5b66\u96d1\u8a8c 59(6): 411-418(2011)", "subitem_description_type": "Other"}]}, "item_10_link_3": {"attribute_name": "\u4fe1\u5dde\u5927\u5b66\u7814\u7a76\u8005\u7dcf\u89a7\u3078\u306e\u30ea\u30f3\u30af", "attribute_value_mlt": [{"subitem_link_text": "KOIZUMI, Tomonobu", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.WakmHhkh.html"}, {"subitem_link_text": "YASUO, Masanori", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.ypnegpkh.html"}]}, "item_10_publisher_4": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u4fe1\u5dde\u533b\u5b66\u4f1a"}]}, "item_10_relation_48": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.11441/shinshumedj.59.411"}], "subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.11441/shinshumedj.59.411", "subitem_relation_type_select": "DOI"}}]}, "item_10_select_64": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_10_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0037-3826", "subitem_source_identifier_type": "PISSN"}]}, "item_10_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0037-3826", "subitem_source_identifier_type": "PISSN"}]}, "item_10_source_id_40": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00120815", "subitem_source_identifier_type": "NCID"}]}, "item_10_text_66": {"attribute_name": "sortkey", "attribute_value_mlt": [{"subitem_text_value": "02"}]}, "item_1627890569677": {"attribute_name": "\u51fa\u7248\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "KOBAYASHI, Takashi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "9346", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KOIZUMI, Tomonobu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "9347", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "YASUO, Masanori", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "9348", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "TSUSHIMA, Kenji", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "9349", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "YAMAMOTO, Hiroshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "9350", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KUBO, Keishi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "9351", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Shinshu_med59-6-02.pdf", "filesize": [{"value": "231.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 231900.0, "url": {"label": "Shinshu_med59-6-02.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/4145/files/Shinshu_med59-6-02.pdf"}, "version_id": "c2d5f565-af9f-4d2f-9950-8a90144af227"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "second-line chemotherapy", "subitem_subject_scheme": "Other"}, {"subitem_subject": "platinum-resistant", "subitem_subject_scheme": "Other"}, {"subitem_subject": "non-small cell lung cancer", "subitem_subject_scheme": "Other"}, {"subitem_subject": "neurotoxicity", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Phase II Trial of Biweekly Paclitaxel and Gemcitabine as Second-Line Chemotherapy for Non-Small Cell Lung Cancer Previously Treated with Platinum-Based Chemotherapy", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Phase II Trial of Biweekly Paclitaxel and Gemcitabine as Second-Line Chemotherapy for Non-Small Cell Lung Cancer Previously Treated with Platinum-Based Chemotherapy", "subitem_title_language": "en"}]}, "item_type_id": "10", "owner": "1", "path": ["461/463/464/487"], "permalink_uri": "http://hdl.handle.net/10091/13507", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2012-01-04"}, "publish_date": "2012-01-04", "publish_status": "0", "recid": "4145", "relation": {}, "relation_version_is_last": true, "title": ["Phase II Trial of Biweekly Paclitaxel and Gemcitabine as Second-Line Chemotherapy for Non-Small Cell Lung Cancer Previously Treated with Platinum-Based Chemotherapy"], "weko_shared_id": -1}