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  1. 050 医学部, 大学院医学系研究科
  2. 0502 紀要・刊行物
  3. 05021 信州医学雑誌
  4. Vol. 57 No. 6

Combination Chemotherapy with Low-dose 5-FU, Cisplatin, and Gemcitabine for Gemcitabine-Refractory Pancreatic Cancer

http://hdl.handle.net/10091/3729
http://hdl.handle.net/10091/3729
cd5dd989-99e5-46e2-b35c-dbfff0682311
名前 / ファイル ライセンス アクション
Shinshu_Med57-6-03.pdf Shinshu_Med57-6-03.pdf (929.2 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2009-12-15
タイトル
言語 en
タイトル Combination Chemotherapy with Low-dose 5-FU, Cisplatin, and Gemcitabine for Gemcitabine-Refractory Pancreatic Cancer
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 second-lin chemotherapy
キーワード
言語 en
主題Scheme Other
主題 pancreatic cancer
キーワード
言語 en
主題Scheme Other
主題 5-FU
キーワード
言語 en
主題Scheme Other
主題 Cisplatin
キーワード
言語 en
主題Scheme Other
主題 Gemcitabine
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 ARAKURA, Norikazu

× ARAKURA, Norikazu

WEKO 9528

en ARAKURA, Norikazu

Search repository
HASEBE, Osamu

× HASEBE, Osamu

WEKO 9529

en HASEBE, Osamu

Search repository
OCHI, Yasuhide

× OCHI, Yasuhide

WEKO 9530

en OCHI, Yasuhide

Search repository
HAMANO, Hideaki

× HAMANO, Hideaki

WEKO 9531

en HAMANO, Hideaki

Search repository
TANAKA, Eiji

× TANAKA, Eiji

WEKO 9532

en TANAKA, Eiji

Search repository
KAWA, Shigeyuki

× KAWA, Shigeyuki

WEKO 9533

en KAWA, Shigeyuki

Search repository
信州大学研究者総覧へのリンク
氏名 TANAKA, Eiji
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.HFDCHekh.html
信州大学研究者総覧へのリンク
氏名 KAWA, Shigeyuki
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.jakeOVkh.html
出版者
出版者 信州医学会
引用
内容記述タイプ Other
内容記述 信州医学雑誌 57(6): 247-253(2009)
書誌情報 信州医学雑誌

巻 57, 号 6, p. 247-253, 発行日 2009-12-10
抄録
内容記述タイプ Abstract
内容記述 Background : No single agent or combination therapy for advanced pancreatic cancer has been reported superior to single-agent GEM, and an effective second-line chemotherapy option is needed for patients who are resistant to first-line GEM therapy. Methods :We analyzed six patients who had disease progression following first-line gemcitabine therapy. Patients received second-line chemotherapy with low dose cisplatin, 5-fluorouracul or S-1,and gemcitabine every 21 days. Results : Two patients showed a partial response (33.3%) and two showed stable disease. Four patients (66.6%) showed a prolonged survival time with partial responses or stable disease.Median survival times were 7 and 11 months from the start of second-line therapy and the start of first-line gemcitabine therapy,respectively. In addition, all patients reported relief from pain and had a favorable performance status. The major toxicities of leucopenia, stomatitis, and diarrhea were found in one patient each.Conclusion : This second-line chemotherapy regimen is an effective option for patients with gemcitabineresistant pancreatic cancer.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 0037-3826
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00120815
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.11441/shinshumedj.57.247
関連名称 10.11441/shinshumedj.57.247
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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