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Although she achieved complete remission (CR) with 45 mg/\u33a1 all-trans retinoic acid (ATRA), multiple liver and spleen abscesses developed as complications during the first consolidation chemotherapy with mitoxantrone and cytarabine. Antibiotic and antifungal treatments were performed for two months, when bone marrow recurrence of APL was detected. After re-remission induction therapy with daunorubicin and cytarabine, one cycle of treatment with 0.15 mg/kg As\u2082O\u2083for five weeks was administered as consolidation therapy because of the therapy-resistant liver and spleen abscesses. After the treatment, PMLRARA chimera mRNA became undetectable. The liver and spleen abscesses gradually reduced, and bone marrow remained in CR for at least 24 months after the As\u2082O\u2083therapy. 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