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Intraoral examination revealed an elastic and soft mass in the middle of the oral floor, measuring 40\u00d735mm. The patient complained of difficulty in tongue mobility. Clinical diagnosis of a cyst was made and the lesion was surgically removed. Histopathological diagnosis was a thyroglossal duct cyst. The patient had been treated for obstructive sleep apnea syndrome (OSAS) at the department of internal medicine in our hospital. The body mass index was 37.11kg/m\u00b2,indicating obesity. On preoperative  polysomnography (PSG) examination, apnea hypopnea index (AHI) was 42.1/h, the lowest SpO\u2082 was 52.0\uff05 and average SpO\u2082 was 96.0\uff05. After removal of the cyst, swelling of the oral floor and dysfunction of the tongue disappeared. Snoring and daytime sleepiness were reduced. On PSG examination after the operation, AHI was 22.7/h, the lowest SpO\u2082 was 67.0\uff05 and the average SpO\u2082 was 97.0\uff05. Moreover, on cephalographic evaluation, MPH, which shows the linear distance from the mandibular plane to the hyoid bone, had decreased from 27mm to 23mm, and IAS, which indicates airway aperture, had increased from 9mm to 11mm. 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