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Although\u3000the thrombin-catalyzed release of fibrinopeptide A from M\uff65I and M\uff65V was almost the same as that, from normal controls, their thrombin-catalyzed fibrin polymerization (TCFP) was markedly impaired as compared with normal fibrinogen. Furthermore, their reptilase-catalyzed fibrin polymerization (RCFP) was much more impaired than their TCFP. In particular, no significant RCFP was observed in the case of M\u30fb\uff29. Taken together our observations suggest that, when the \u2018\uff21\u2019site is impaired in TCFP, \u2018a-B\u2019\u0027binding of M\uff65V may play a more important role, and  when the \u2018a\u2019site is impaired, \u2018b-A\u2019and/or \u2018b-\uff22\u2019interaction may not compensate for the polymerization of M\uff65I.", "subitem_description_type": "Abstract"}]}, "item_10_description_30": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7\uff08\u30b3\u30f3\u30c6\u30f3\u30c4\u306e\u7a2e\u985e\uff09", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_10_description_31": {"attribute_name": "\u30d5\u30a9\u30fc\u30de\u30c3\u30c8\uff1amime\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_10_description_5": {"attribute_name": "\u5f15\u7528", "attribute_value_mlt": [{"subitem_description": "\u7d00\u8981 27: 57-66(2002)", "subitem_description_type": 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