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抗サイログロブリン抗体および抗マイクロゾーム抗体測定法の研究
http://hdl.handle.net/10091/5153
0e124e64-7bfb-4829-bc0d-bcbd587c5645
名前 / ファイル | ライセンス | アクション | |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2010-03-01 | |||||
タイトル | ||||||
タイトル | 抗サイログロブリン抗体および抗マイクロゾーム抗体測定法の研究 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Thyroglobulin Autoantibody | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Microsomal Autoantibody | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Positive incidence of Autoantibodies | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Tg inhibition test | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Enzyme immunoassay | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他(別言語等)のタイトル | ||||||
その他のタイトル | Studies on Measurement of Anti-Thyroglobulin and Anti-Microsomal Autoantibodies | |||||
著者 |
加藤, 亮二
× 加藤, 亮二× 菅谷, 昭× 飯田, 太 |
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出版者 | ||||||
出版者 | 信州大学医療技術短期大学部 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 紀要 17: 15-21(1992) | |||||
書誌情報 |
紀要 巻 17, p. 15-21, 発行日 1992-02-28 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | SERODIA AMC (PA-AMC) and SERODIA ATG (PA-ATG) with gelatin particle agglutination (PA) are most widely used for the determination of anti-thyroglobulin antibody (TgAb) and anti-microsomal antibody (McAb) in laboratory medicine. However, the positive incidence of Hasimoto's disease in these measurements was 80% with PA-AMC and 30% with PA-ATG respectively. We tried to define the causes of the difference produced between PA-ATG and PA-AMC by follwing experiments. 1. An Inhibition test in which Tg antigen was added to both PA-AMC and PA-ATG reagent system in order to identify positive incidence. 2. An enzyme immunoassay (EIA) in which purified Mc antigen (absolutely free from Tg) and purified Tg antigen were used in order to identify non-specific positive reactions. Twenty-six percent of the false positive sera appeared in PA-AMC positive sera. However, no false positive sera were observed in PA-ATG positive sera. These results suggested that Mc antigen in reagent could have been contaminated with Tg Antigen and also McAb could have a cross reactivity to Tg. We concluded that Tg added PA-AMC system, Inhibition method, or Thyroid peroxidase (TPO) method were most suitable for the determination of serum McAb. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0385-1982 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10402438 |