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  1. 050 医学部, 大学院医学系研究科
  2. 0502 紀要・刊行物
  3. 05022 医療技術短期大学部紀要
  4. Vol. 17

抗サイログロブリン抗体および抗マイクロゾーム抗体測定法の研究

http://hdl.handle.net/10091/5153
0e124e64-7bfb-4829-bc0d-bcbd587c5645
名前 / ファイル ライセンス アクション
Allied_Med17_02.pdf Allied_Med17_02.pdf (435.7 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2010-03-01
タイトル
タイトル 抗サイログロブリン抗体および抗マイクロゾーム抗体測定法の研究
言語
言語 jpn
キーワード
主題Scheme Other
主題 Thyroglobulin Autoantibody
キーワード
主題Scheme Other
主題 Microsomal Autoantibody
キーワード
主題Scheme Other
主題 Positive incidence of Autoantibodies
キーワード
主題Scheme Other
主題 Tg inhibition test
キーワード
主題Scheme Other
主題 Enzyme immunoassay
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他(別言語等)のタイトル
その他のタイトル Studies on Measurement of Anti-Thyroglobulin and Anti-Microsomal Autoantibodies
著者 加藤, 亮二

× 加藤, 亮二

WEKO 16894

加藤, 亮二

Search repository
菅谷, 昭

× 菅谷, 昭

WEKO 16895

菅谷, 昭

Search repository
飯田, 太

× 飯田, 太

WEKO 16896

飯田, 太

Search repository
出版者
出版者 信州大学医療技術短期大学部
引用
内容記述タイプ Other
内容記述 紀要 17: 15-21(1992)
書誌情報 紀要

巻 17, p. 15-21, 発行日 1992-02-28
抄録
内容記述タイプ Abstract
内容記述 SERODIA AMC (PA-AMC) and SERODIA ATG (PA-ATG) with gelatin particle agglutination (PA) are most widely used for the determination of anti-thyroglobulin antibody (TgAb) and anti-microsomal antibody (McAb) in laboratory medicine. However, the positive incidence of Hasimoto's disease in these measurements was 80% with PA-AMC and 30% with PA-ATG respectively. We tried to define the causes of the difference produced between PA-ATG and PA-AMC by follwing experiments. 1. An Inhibition test in which Tg antigen was added to both PA-AMC and PA-ATG reagent system in order to identify positive incidence. 2. An enzyme immunoassay (EIA) in which purified Mc antigen (absolutely free from Tg) and purified Tg antigen were used in order to identify non-specific positive reactions. Twenty-six percent of the false positive sera appeared in PA-AMC positive sera. However, no false positive sera were observed in PA-ATG positive sera. These results suggested that Mc antigen in reagent could have been contaminated with Tg Antigen and also McAb could have a cross reactivity to Tg. We concluded that Tg added PA-AMC system, Inhibition method, or Thyroid peroxidase (TPO) method were most suitable for the determination of serum McAb.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ ISSN
収録物識別子 0385-1982
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN10402438
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