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Since the mutation was not detected in peripheral blood leukocytes 9 months before the diagnosis, biallelic somatic inactivation of the TP53 gene might play an important role in the occurrence of MDS. His poor outcome might be associated with resistance to chemotherapy/radiation of a minor clone with both TP53 gene alteration and MLL duplication that already existed at onset. (C) 2011 Elsevier Ltd. 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Genetic analysis of TP53 in childhood myelodysplastic syndrome and juvenile myelomonocytic leukemia
http://hdl.handle.net/10091/16018
http://hdl.handle.net/10091/16018352a23aa-809c-4811-85e7-cad88dd02f7e
名前 / ファイル | ライセンス | アクション |
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H23kou886_Saito.pdf (752.7 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2012-10-01 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Genetic analysis of TP53 in childhood myelodysplastic syndrome and juvenile myelomonocytic leukemia | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | MDS, JMML, TP53, Childhood, Clone, Biallelic inactivation, MLL duplication | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Saito, Shoji
× Saito, Shoji× Matsuda, Kazuyuki× Taira, Chiaki× Sano, Kenji× Tanaka-Yanagisawa, Miyuki× Yanagisawa, Ryu× Nakazawa, Yozo× Sakashita, Kazuo× Shiohara, Masaaki× Koike, Kenichi |
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出版者 | ||||||
出版者 | PERGAMON-ELSEVIER SCIENCE LTD | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | LEUKEMIA RESEARCH. 35(12):1578-1584 (2011) | |||||
書誌情報 |
LEUKEMIA RESEARCH 巻 35, 号 12, p. 1578-1584, 発行日 2011-12 |
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内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 信州大学博士(医学)・学位論文・平成23年3月31日授与(甲第886号)・齋藤章治 | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0145-2126 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00716755 | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=21784522 | |||||
関連名称 | 21784522 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.leukres.2011.06.027 | |||||
関連名称 | 10.1016/j.leukres.2011.06.027 | |||||
権利 | ||||||
権利情報 | Copyright© 2011 Elsevier Ltd. | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000296721500009 |