| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2012-10-03 |
| タイトル |
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|
タイトル |
Risk Evaluation for Coronary Artery Disease in Patients With Impaired Glucose Tolerance After a Successful Coronary Intervention |
| 言語 |
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言語 |
eng |
| DOI |
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|
|
関連識別子 |
https://doi.org/10.1097/RLU.0b013e318217aeac |
|
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関連名称 |
10.1097/RLU.0b013e318217aeac |
| キーワード |
|
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主題 |
positron emission tomography (PET), coronary artery disease, impaired glucose tolerance (IGT), coronary risk factor, endothelial function |
| 資源タイプ |
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|
資源 |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 著者 |
Horigome, Mitsuaki
Hattori, Naoya
Kasai, Hiroki
Horigome, Miki
Sakurai, Shumpei
Oguchi, Kazuhiro
Ikeda, Uichi
|
| 出版者 |
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出版者 |
LIPPINCOTT WILLIAMS & WILKINS |
| 引用 |
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内容記述 |
CLINICAL NUCLEAR MEDICINE. 36(7):546-552 (2011) |
| 書誌情報 |
CLINICAL NUCLEAR MEDICINE
巻 36,
号 7,
p. 546-552,
発行日 2011-07
|
| 内容記述 |
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内容記述タイプ |
Other |
|
内容記述 |
信州大学博士（医学）・学位論文・平成23年3月31日授与（甲第880号）・堀込充章 |
| 内容記述 |
|
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内容記述タイプ |
Other |
|
内容記述 |
This is a non-final version of an article published in final form in CLINICAL NUCLEAR MEDICINE. 36(7):546-552 (2011) |
| 抄録 |
|
|
内容記述 |
Purpose: Patients with coronary artery disease (CAD) often have risk factors that may influence endothelial function. The purpose of this study was to evaluate the endothelial function and its association with coronary risk factors after percutaneous coronary intervention (PCI). Materials and Methods: A total of 14 patients with impaired glucose tolerance and CAD underwent positron emission tomography with N-13 ammonia to measure myocardial blood flow (MBF) at rest and during a cold pressor test (CPT), to estimate endothelial function as a percent increase (%increase) of MBF. The results were compared among normal segments (normal), reperfused segments with PCI (PCI), and nonculprit CAD segments without PCI (non-PCI). Correlations between the %increase and major risk factors were also investigated. Results: CPT induced significant increase in MBF in all groups. The %increase of normal, non-PCI, and PCI groups were 33% +/- 22%, 21% +/- 23%, and 26% +/- 23%, respectively. Comparison with risk factors demonstrated significant correlations only in the non-PCI group. Specifically, there were negative correlations between %increase and fasting blood sugar (r = -0.64, P < 0.05), hemoglobin A1c (r = -0.74, P < 0.05), total cholesterol (r = -0.87, P < 0.05), triglyceride (r = -0.71, P < 0.05), and low-density lipoprotein cholesterol (r = -0.92, P < 0.005), respectively. Conclusions: Although impaired glucose tolerance patients with a PCI-treated coronary stenosis showed preserved response to CPT, the %increase negatively correlated with risk factors in the non-PCI segments. Therefore, coronary risk factors may affect CAD lesions in PCI-treated patients. |
| 資源タイプ（コンテンツの種類） |
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| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0363-9762 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA0060791X |
| PubMed |
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|
識別子タイプ |
PMID |
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関連識別子 |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=21637056 |
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関連名称 |
21637056 |
| 出版タイプ |
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|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| WoS |
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|
URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000291271000015 |
H23Kou880_Horigome.pdf (347.7 kB)
