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Electrophysiological features of familial amyloid polyneuropathy in endemic area
http://hdl.handle.net/10091/16949
http://hdl.handle.net/10091/16949305c0c5d-1c3c-44a7-a0d9-1786d15afafb
名前 / ファイル | ライセンス | アクション |
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Electrophysiological_features_familial_amyloid_polyneuropathy.pdf (274.6 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-04-23 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Electrophysiological features of familial amyloid polyneuropathy in endemic area | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | Familial amyloid polyneuropathy, peripheral nerve dysfunction, amyloid, transthyretin, nerve conduction study | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Kodaira, Minori
× Kodaira, Minori× Morita, Hiroshi× Shimojima, Yoshio× Ikeda, Shu-ichi |
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信州大学研究者総覧へのリンク | ||||||
氏名 | Kodaira, Minori | |||||
URL | https://soar-rd.shinshu-u.ac.jp/profile/ja.jmfUgUkh.html | |||||
信州大学研究者総覧へのリンク | ||||||
氏名 | Morita, Hiroshi | |||||
URL | https://soar-rd.shinshu-u.ac.jp/profile/ja.HUyNHhkh.html | |||||
出版者 | ||||||
出版者 | INFORMA HEALTHCARE | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS. 18(1):10-18 (2011) | |||||
書誌情報 |
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS 巻 18, 号 1, p. 10-18, 発行日 2011-05 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The process of deterioration of peripheral nerve function in familial amyloid polyneuropathy (FAP) with amyloidogenic transthyretin (ATTR) Val30Met has not been systematically evaluated hitherto. We performed nerve conduction studies in 69 patients with FAP with ATTR Val30Met from one of the endemic areas in Japan. Sensory conduction velocity (SCV), motor conduction velocity (MCV), the size of the compound muscle action potential (CMAP) and distal latency (DL) were measured in the ulnar and tibial nerves. SCV was evaluated using the orthodromic method with needle recording electrodes. These electrophysiological parameters were compared with clinical stage of FAP and duration of neuropathy. When subjects noted minimal neuropathic symptoms only in the feet, motor and sensory nerve function in both the hands and feet had already been disturbed. Sensory nerve action potential on the foot disappeared more rapidly than CMAP. CMAP on foot muscle rapidly decreased during the initial 2 years and completely disappeared within 10 years. The duration of illness and deterioration parameters (CMAP of the abductor digiti minimi muscle, MCV and SCV of the ulnar nerve and DL of both ulnar and tibial nerves) were linearly correlated. CMAP was the most sensitive and reliable parameter to evaluate motor nerve degeneration in FAP.</. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 1350-6129 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11096426 | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | https://pubmed.ncbi.nlm.nih.gov/21261557 | |||||
関連名称 | 21261557 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.3109/13506129.2010.548424 | |||||
関連名称 | 10.3109/13506129.2010.548424 | |||||
権利 | ||||||
権利情報 | Copyright© 2011 Informa UK, Ltd. | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000286994000003 |