{"_buckets": {"deposit": "ce5cb6d1-0da8-445c-b57f-3849c3d3f6f3"}, "_deposit": {"id": "8068", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "8068"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00008068"}, "item_6_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2011-09", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "9", "bibliographicPageEnd": "909", "bibliographicPageStart": "904", "bibliographicVolumeNumber": "41", "bibliographic_titles": [{"bibliographic_title": "HEPATOLOGY RESEARCH"}]}]}, "item_6_description_20": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "A 58-year-old woman with chronic hepatitis C developed interstitial pneumonia (IP) while undergoing pegylated interferon (PEG IFN)-alpha-2a and ribavirin (RBV) therapy. Serum levels of sialylated carbohydrate antigen KL-6 (KL-6), a known marker of disease activity in fibrosing lung disorders, had been regularly measured once a month for early detection of IP, and had begun rising noticeably from 12 weeks to 540 U/mL at 33 weeks of treatment. On examination, remarkable fine crackles were detected by dorsal auscultation and bilateral ground-glass opacities and reticular shadows were depicted by computed tomography. The patient successfully recovered from her early-stage pneumonia by immediate discontinuation of therapy, which indicates that regular monitoring of serum KL-6 may be effective for avoidance of IP progression induced by PEG IFN and RBV therapy.", "subitem_description_type": "Abstract"}]}, "item_6_description_30": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7\uff08\u30b3\u30f3\u30c6\u30f3\u30c4\u306e\u7a2e\u985e\uff09", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "\u5f15\u7528", "attribute_value_mlt": [{"subitem_description": "HEPATOLOGY RESEARCH. 41(9):904-909 (2011)", "subitem_description_type": "Other"}]}, "item_6_link_3": {"attribute_name": "\u4fe1\u5dde\u5927\u5b66\u7814\u7a76\u8005\u7dcf\u89a7\u3078\u306e\u30ea\u30f3\u30af", "attribute_value_mlt": [{"subitem_link_text": "Joshita, Satoru", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.PeLNbVym.html"}, {"subitem_link_text": "Umemura, Takeji", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.ymSpgpkh.html"}, {"subitem_link_text": "Tanaka, Eiji", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.HFDCHekh.html"}]}, "item_6_link_67": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000294739200011"}]}, "item_6_publisher_4": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "WILEY-BLACKWELL"}]}, "item_6_relation_47": {"attribute_name": "PubMed", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "21884341"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search\u0026DB=pubmed\u0026term=21884341", "subitem_relation_type_select": "PMID"}}]}, "item_6_relation_48": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1111/j.1872-034X.2011.00837.x"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://dx.doi.org/10.1111/j.1872-034X.2011.00837.x", "subitem_relation_type_select": "DOI"}}]}, "item_6_rights_62": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "Copyright\u00a9 2011 The Japan Society of Hepatology. The definitive version is available at www.blackwell-synergy.com"}]}, "item_6_select_64": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_6_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1386-6346", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1386-6346", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_40": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA11140867", "subitem_source_identifier_type": "NCID"}]}, "item_6_text_69": {"attribute_name": "wosonly authkey", "attribute_value_mlt": [{"subitem_text_value": "interstitial pneumonia; KL-6; pegylated interferon; ribavirin"}]}, "item_6_text_70": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "CHRONIC ACTIVE HEPATITIS; PLUS RIBAVIRIN; INFECTION"}]}, "item_6_textarea_68": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "A 58-year-old woman with chronic hepatitis C developed interstitial pneumonia (IP) while undergoing pegylated interferon (PEG IFN)-alpha-2a and ribavirin (RBV) therapy. Serum levels of sialylated carbohydrate antigen KL-6 (KL-6), a known marker of disease activity in fibrosing lung disorders, had been regularly measured once a month for early detection of IP, and had begun rising noticeably from 12 weeks to 540 U/mL at 33 weeks of treatment. On examination, remarkable fine crackles were detected by dorsal auscultation and bilateral ground-glass opacities and reticular shadows were depicted by computed tomography. The patient successfully recovered from her early-stage pneumonia by immediate discontinuation of therapy, which indicates that regular monitoring of serum KL-6 may be effective for avoidance of IP progression induced by PEG IFN and RBV therapy."}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ichikawa-Yamada,  Yuki"}], "nameIdentifiers": [{"nameIdentifier": "22398", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Joshita,  Satoru"}], "nameIdentifiers": [{"nameIdentifier": "22399", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tsukahara,  Yoshinori"}], "nameIdentifiers": [{"nameIdentifier": "22400", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kimura,  Takefumi"}], "nameIdentifiers": [{"nameIdentifier": "22401", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Morita,  Susumu"}], "nameIdentifiers": [{"nameIdentifier": "22402", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kamijo,  Atsushi"}], "nameIdentifiers": [{"nameIdentifier": "22403", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Umemura,  Takeji"}], "nameIdentifiers": [{"nameIdentifier": "22404", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ichijo,  Tetsuya"}], "nameIdentifiers": [{"nameIdentifier": "22405", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsumoto,  Akihiro"}], "nameIdentifiers": [{"nameIdentifier": "22406", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshizawa,  Kaname"}], "nameIdentifiers": [{"nameIdentifier": "22407", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka,  Eiji"}], "nameIdentifiers": [{"nameIdentifier": "22408", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-25"}], "displaytype": "detail", "download_preview_message": "", "filename": "Early_detection_interstitial_pneumonia_monitoring_KL-6.pdf", "filesize": [{"value": "322.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 3229000, "url": {"label": "Early_detection_interstitial_pneumonia_monitoring_KL-6.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/8068/files/Early_detection_interstitial_pneumonia_monitoring_KL-6.pdf"}, "version_id": "3b1ee45e-a9f4-4137-8493-2dcfc10d9f56"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "interstitial pneumonia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "KL-6", "subitem_subject_scheme": "Other"}, {"subitem_subject": "pegylated interferon", "subitem_subject_scheme": "Other"}, {"subitem_subject": "ribavirin", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Early detection of interstitial pneumonia by monitoring KL-6 in a chronic hepatitis C patient undergoing pegylated interferon and ribavirin therapy", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Early detection of interstitial pneumonia by monitoring KL-6 in a chronic hepatitis C patient undergoing pegylated interferon and ribavirin therapy"}]}, "item_type_id": "6", "owner": "1", "path": ["882/883"], "permalink_uri": "http://hdl.handle.net/10091/16880", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2013-04-01"}, "publish_date": "2013-04-01", "publish_status": "0", "recid": "8068", "relation": {}, "relation_version_is_last": true, "title": ["Early detection of interstitial pneumonia by monitoring KL-6 in a chronic hepatitis C patient undergoing pegylated interferon and ribavirin therapy"], "weko_shared_id": 3}