{"_buckets": {"deposit": "c41b2fd5-4b51-4d90-ba0a-342d300b6cd5"}, "_deposit": {"id": "10248", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "10248"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00010248"}, "item_6_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2013-12-25", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "52", "bibliographicPageEnd": "7192", "bibliographicPageStart": "7188", "bibliographicVolumeNumber": "54", "bibliographic_titles": [{"bibliographic_title": "TETRAHEDRON LETTERS"}]}]}, "item_6_description_20": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Total synthesis of prodelphinidin B1, B2, and B4 has been accomplished. The key step is Lewis acid-mediated equimolar condensations between an epigallocatechin and/or a gallocatechin nucleophile and an epigallocatechin and/or a gallocatechin electrophile. The antitumor effects of synthetic prodelphinidin B1-B4 against human PC-3 prostate cancer cell lines have been investigated. These compounds showed significant antitumor effects. Their activity seemed to be little bit stronger than EGCG and prodelphinidin B3, known antitumor agent.", "subitem_description_type": "Abstract"}]}, "item_6_description_30": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7\uff08\u30b3\u30f3\u30c6\u30f3\u30c4\u306e\u7a2e\u985e\uff09", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "\u5f15\u7528", "attribute_value_mlt": [{"subitem_description": "TETRAHEDRON LETTERS. 54(52):7188-7192 (2013)", "subitem_description_type": "Other"}]}, "item_6_link_3": {"attribute_name": "\u4fe1\u5dde\u5927\u5b66\u7814\u7a76\u8005\u7dcf\u89a7\u3078\u306e\u30ea\u30f3\u30af", "attribute_value_mlt": [{"subitem_link_text": "Fujii, Hiroshi", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.WhymjeSh.html"}, {"subitem_link_text": "Makabe, Hidefumi", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.jFSaPUkh.html"}]}, "item_6_link_67": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000327805800025"}]}, "item_6_publisher_4": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "PERGAMON-ELSEVIER SCIENCE LTD"}]}, "item_6_relation_48": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1016/j.tetlet.2013.10.113"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://dx.doi.org/10.1016/j.tetlet.2013.10.113", "subitem_relation_type_select": "DOI"}}]}, "item_6_rights_62": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "Copyright\u00a9 2013 Elsevier Ltd."}]}, "item_6_select_64": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_6_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0040-4039", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0040-4039", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_40": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00861801", "subitem_source_identifier_type": "NCID"}]}, "item_6_text_69": {"attribute_name": "wosonly authkey", "attribute_value_mlt": [{"subitem_text_value": "Polyphenols; Synthesis; Natural product; Anticancer agents"}]}, "item_6_text_70": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "EFFICIENT STEREOSELECTIVE-SYNTHESIS; MEDIATED EQUIMOLAR CONDENSATION; POLYMERASE INHIBITORY-ACTIVITY; RADICAL SCAVENGING ACTIVITY; CYCLE ARREST; POLYPHENOL CHEMISTRY; SYSTEMATIC SYNTHESIS; MAILLARD REACTION; INTERFLAVAN BOND; PROCYANIDIN B1"}]}, "item_6_textarea_68": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "Total synthesis of prodelphinidin B1, B2, and B4 has been accomplished. The key step is Lewis acid-mediated equimolar condensations between an epigallocatechin and/or a gallocatechin nucleophile and an epigallocatechin and/or a gallocatechin electrophile. The antitumor effects of synthetic prodelphinidin B1-B4 against human PC-3 prostate cancer cell lines have been investigated. These compounds showed significant antitumor effects. Their activity seemed to be little bit stronger than EGCG and prodelphinidin B3, known antitumor agent. \u00a9 2013 Elsevier Ltd. All rights reserved."}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Fujii,  Wataru"}], "nameIdentifiers": [{"nameIdentifier": "32361", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Toda,  Kazuya"}], "nameIdentifiers": [{"nameIdentifier": "32362", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsumoto,  Kiriko"}], "nameIdentifiers": [{"nameIdentifier": "32363", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawaguchi,  Koichiro"}], "nameIdentifiers": [{"nameIdentifier": "32364", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawahara,  Sei-ichi"}], "nameIdentifiers": [{"nameIdentifier": "32365", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hattori,  Yasunao"}], "nameIdentifiers": [{"nameIdentifier": "32366", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Fujii,  Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "32367", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Makabe,  Hidefumi"}], "nameIdentifiers": [{"nameIdentifier": "32368", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-25"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Syntheses_prodelphinidin_B1_B2_B4_their_antitumor_activities.pdf", "filesize": [{"value": "1.0 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1000000.0, "url": {"label": "Syntheses_prodelphinidin_B1_B2_B4_their_antitumor_activities.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/10248/files/Syntheses_prodelphinidin_B1_B2_B4_their_antitumor_activities.pdf"}, "version_id": "9dd86b21-48df-42e6-bf44-3e369ed650ae"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Polyphenols", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Synthesis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Natural product", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Anticancer agents", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Syntheses of prodelphinidin B1, B2, and B4 and their antitumor activities against human PC-3 prostate cancer cell lines", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Syntheses of prodelphinidin B1, B2, and B4 and their antitumor activities against human PC-3 prostate cancer cell lines"}]}, "item_type_id": "6", "owner": "1", "path": ["1016/1017"], "permalink_uri": "http://hdl.handle.net/10091/17851", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2014-09-05"}, "publish_date": "2014-09-05", "publish_status": "0", "recid": "10248", "relation": {}, "relation_version_is_last": true, "title": ["Syntheses of prodelphinidin B1, B2, and B4 and their antitumor activities against human PC-3 prostate cancer cell lines"], "weko_shared_id": null}