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Anti-Allergic Properties of a Matured Fruit Extract of the Date Palm Tree (Phoenix dactylifera L.) in Mite-Sensitized Mice
http://hdl.handle.net/10091/17245
http://hdl.handle.net/10091/17245a26ba47d-5bff-4dae-8443-6288092607d8
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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公開日 | 2013-12-02 | |||||||||
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タイトル | Anti-Allergic Properties of a Matured Fruit Extract of the Date Palm Tree (Phoenix dactylifera L.) in Mite-Sensitized Mice | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
DOI | ||||||||||
関連識別子 | https://doi.org/10.3177/jnsv.58.272 | |||||||||
関連名称 | 10.3177/jnsv.58.272 | |||||||||
キーワード | ||||||||||
主題 | anti-allergic property, date polyphenol, Th1/Th2 balance, IgE-producing plasma cell, mast cell | |||||||||
資源タイプ | ||||||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||
タイプ | journal article | |||||||||
著者 |
Karasawa, Koji
× Karasawa, Koji
× Otani, Hajime
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出版者 | ||||||||||
出版者 | CENTER ACADEMIC PUBL JAPAN | |||||||||
引用 | ||||||||||
内容記述 | JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY. 58(4):272-277 (2012) | |||||||||
書誌情報 |
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY 巻 58, 号 4, p. 272-277, 発行日 2012-08 |
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抄録 | ||||||||||
内容記述 | The effects of oral ingestion of a hot water extract of matured fruit of the date palm tree (Phoenix dactylifera L.) on allergic responses were investigated in mite-sensitized mice. Sneezing and nose rubbing events in mice given a date extract-added diet were significantly lower than in those given an extract-free (control) diet. The serum total and mite antigen-specific immunoglobulin (Ig) E levels, and the number of spleen interleukin-4(+)CD4(+), IgE(+)B220(+) and Fc epsilon RI alpha(+)CD117(+) cells was significantly lower in mice given the date extract- added diet than in those given the control diet. Chlorogenic acid, pelargonin and ferulic acid significantly reduced the number of IgE(+)B220(+) cells, while chlorogenic acid and pelargonin significantly decreased the number of Fc epsilon RI alpha(+)CD117(+) cells in mouse spleen cell cultures. These results suggest that some polyphenols in the date may reduce mite-induced allergic symptoms in mice via a decrease in the number of IgE-producing plasma cells and high-affinity IgE receptor-expressing mast cells. | |||||||||
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収録物識別子タイプ | ISSN | |||||||||
収録物識別子 | 0301-4800 | |||||||||
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収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AA00703822 | |||||||||
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出版タイプ | AM | |||||||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||
WoS | ||||||||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000308382500007 |
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Karasawa, Koji, Otani, Hajime, 2012, Anti-Allergic Properties of a Matured Fruit Extract of the Date Palm Tree (Phoenix dactylifera L.) in Mite-Sensitized Mice: CENTER ACADEMIC PUBL JAPAN, 272–277 p.
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