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  1. 070 農学部, 大学院農学研究科
  2. 0701 学術論文

Anti-allergic Properties of a Fruit Extract of Prune (Prunus domestica L.), in Mite-sensitized BALB/c Mice

http://hdl.handle.net/10091/17244
97d457d1-d6ac-4022-93ad-eb2c2e313038
名前 / ファイル ライセンス アクション
Anti-allergic_Properties_Fruit_Extract_Prune5.pdf Anti-allergic_Properties_Fruit_Extract_Prune5.pdf (535.9 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2013-12-02
タイトル
言語 en
タイトル Anti-allergic Properties of a Fruit Extract of Prune (Prunus domestica L.), in Mite-sensitized BALB/c Mice
言語
言語 eng
キーワード
主題Scheme Other
主題 anti-allergic property
キーワード
主題Scheme Other
主題 prune extract
キーワード
主題Scheme Other
主題 immunoglobulin E
キーワード
主題Scheme Other
主題 helper T cell subsets
キーワード
主題Scheme Other
主題 degranulation
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Karasawa, Koji

× Karasawa, Koji

WEKO 32453

Karasawa, Koji

Search repository
Miyashita, Ryoji

× Miyashita, Ryoji

WEKO 32454

Miyashita, Ryoji

Search repository
Otani, Hajime

× Otani, Hajime

WEKO 32455

Otani, Hajime

Search repository
出版者
出版者 KARGER
引用
内容記述タイプ Other
内容記述 FOOD SCIENCE AND TECHNOLOGY RESEARCH. 18(5):755-760 (2012)
書誌情報 FOOD SCIENCE AND TECHNOLOGY RESEARCH

巻 18, 号 5, p. 755-760, 発行日 2012-09
抄録
内容記述タイプ Abstract
内容記述 The effects of oral ingestion of a hot water extract of prune (Prunus domestica L.) fruit on allergic responses were investigated in mite-sensitized BALB/c mice. The number of sneezing events in mice given the extract-added diet was significantly lower than in mice given the extract-free diet. Serum mite allergen-specific immunoglobulin E levels were significantly lower in mice given the extract-added diet than in mice given the extract-free diet. In contrast, the ratio of splenic IFN-gamma(+)CD4(+) cells/IL-4(+)CD4(+) cells was higher in mice given the extract-added diet. Expression levels of Stat6, Btk and Stim1 mRNAs in spleen cells of mice given the extract-added diet were significantly lower than in mice given the extract-free diet. These results suggest that the prune extract may reduce type I allergic symptoms in mice via the adjustment of type 1 helper T cell/type 2 helper T cell balance and the suppression of mast cell degranulation.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ ISSN
収録物識別子 1344-6606
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA11320122
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.3136/fstr.18.755
関連名称
関連名称 10.3136/fstr.18.755
権利
権利情報 Copyright (c) 2012 Japanese Society for Food Science and Technology
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000310098300021
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