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Anti-allergic effects of a mixture of Saccharomyces cerevisiae and its specific goat's milk immunoglobulin G rich fraction on ovalbumin sensitized BALB/c mice
http://hdl.handle.net/10091/13191
http://hdl.handle.net/10091/131915495759b-583b-4854-b8ce-045f9e5d9a86
| 名前 / ファイル | ライセンス | アクション |
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Anti-allergic_effects_mixture_Saccharomyces.pdf (1.3 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||
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| 公開日 | 2011-06-20 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Anti-allergic effects of a mixture of Saccharomyces cerevisiae and its specific goat's milk immunoglobulin G rich fraction on ovalbumin sensitized BALB/c mice | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| キーワード | ||||||||||||
| 主題 | 14 Allergy, 14 Allergie, mouse model, Mausmodell, antiallergic effects, antiallergische Effekte, Saccharomyces cerevisiaelgoal's milk, Saccharomyces cerevisiaelZiegenmilch-lgG | |||||||||||
| 資源タイプ | ||||||||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| タイプ | journal article | |||||||||||
| 著者 |
Sekekimura, Yumi
× Sekekimura, Yumi
× Shimosato, Takeshi
× Otani, Hajime
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| 信州大学研究者総覧へのリンク | ||||||||||||
| 氏名 | Shimosato, Takeshi | |||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.ONLCjFkV.html | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | A V A AGRARVERLAG | |||||||||||
| 引用 | ||||||||||||
| 内容記述 | MILCHWISSENSCHAFT-MILK SCIENCE INTERNATIONAL. 66(1): 7-10(2011) | |||||||||||
| 書誌情報 |
MILCHWISSENSCHAFT-MILK SCIENCE INTERNATIONAL 巻 66, 号 1, p. 7-10, 発行日 2011 |
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| 抄録 | ||||||||||||
| 内容記述 | In this study, we investigated the effects of oral ingestion of Saccharomyces (S.) cerevisiae and its specific immunoglobulin (Ig) G-rich fraction, prepared from goat's milk, on immune function in an allergic rhinitis mouse model, ovalbumin (OVA)-sensitized BALB/c mice. Sneezing activity in mice that were administered a feed containing a mixture of S. cerevisiae and its specific goat's milk IgG-rich fraction (mixture group) was significantly lower than that in mice administered the mixture-free feed (control group) at age 11 and 12 weeks, although the activity in mice that were given a feed containing S. cerevisiae (yeast group) was similar to that of the control group. We found that the ratio of spleen interferon-gamma(+)CD4(+) cell/interleukin (IL)-4(+)CD4(+) cell was higher in the mixture and yeast groups than the control group. The number of spleen CD80(+)CD11b(+) cells was significantly lower in the mixture and yeast groups than the control group. In contrast, the numbers of spleen CD122(+)CD8 alpha(+) and IL-10(+)CD4(+) cells were significantly higher in the mixture group than the control and yeast groups while the numbers of IgE(+)B220(+) and Fc epsilon RI alpha(+)CD117(+) cells were significantly lower in the mixture group. These results suggested that the mixture of S. cerevisiae and its specific goat's milk IgG-rich fraction reduced OVA-induced allergic symptoms in BALB/c mice via the induction of suppressor T cells and the reduction of Ig E-producing cells and high affinity IgE receptor-positive mast cells rather than the adjustment of the Th1/Th2 balance. | |||||||||||
| 資源タイプ（コンテンツの種類） | ||||||||||||
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| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 0026-3788 | |||||||||||
| 書誌レコードID | ||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||
| 収録物識別子 | AA00285427 | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| WoS | ||||||||||||
| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000287643600002 | |||||||||||
