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  1. 070 農学部, 大学院農学研究科 (Faculty&Graduate School of Agriculture)
  2. 0701 学術論文 (Journal Articles)

Anti-allergic effects of a mixture of Saccharomyces cerevisiae and its specific goat's milk immunoglobulin G rich fraction on ovalbumin sensitized BALB/c mice

http://hdl.handle.net/10091/13191
5495759b-583b-4854-b8ce-045f9e5d9a86
プレビュー
名前 / ファイル ライセンス Actions
Anti-allergic_effects_mixture_Saccharomyces.pdf Anti-allergic_effects_mixture_Saccharomyces.pdf (1.3 MB)
item type 学術雑誌論文 / Journal Article(1)
公開日 2011-06-20
タイトル
タイトル Anti-allergic effects of a mixture of Saccharomyces cerevisiae and its specific goat's milk immunoglobulin G rich fraction on ovalbumin sensitized BALB/c mice
言語
言語 eng
キーワード
主題 14 Allergy
キーワード
主題 14 Allergie
キーワード
主題 mouse model
キーワード
主題 Mausmodell
キーワード
主題 antiallergic effects
キーワード
主題 antiallergische Effekte
キーワード
主題 Saccharomyces cerevisiaelgoal's milk
キーワード
主題 Saccharomyces cerevisiaelZiegenmilch-lgG
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Sekekimura, Yumi

× Sekekimura, Yumi

WEKO 32615

Sekekimura, Yumi

Search repository
Shimosato, Takeshi

× Shimosato, Takeshi

WEKO 32616

Shimosato, Takeshi

Search repository
Otani, Hajime

× Otani, Hajime

WEKO 32617

Otani, Hajime

Search repository
信州大学研究者総覧へのリンク
Shimosato, Takeshi
http://soar-rd.shinshu-u.ac.jp/profile/ja.ONLCjFkV.html
出版者
出版者 A V A AGRARVERLAG
引用
内容記述タイプ Other
内容記述 MILCHWISSENSCHAFT-MILK SCIENCE INTERNATIONAL. 66(1): 7-10(2011)
書誌情報 MILCHWISSENSCHAFT-MILK SCIENCE INTERNATIONAL

巻 66, 号 1, p. 7-10, 発行日 2011
抄録
内容記述タイプ Abstract
内容記述 In this study, we investigated the effects of oral ingestion of Saccharomyces (S.) cerevisiae and its specific immunoglobulin (Ig) G-rich fraction, prepared from goat's milk, on immune function in an allergic rhinitis mouse model, ovalbumin (OVA)-sensitized BALB/c mice. Sneezing activity in mice that were administered a feed containing a mixture of S. cerevisiae and its specific goat's milk IgG-rich fraction (mixture group) was significantly lower than that in mice administered the mixture-free feed (control group) at age 11 and 12 weeks, although the activity in mice that were given a feed containing S. cerevisiae (yeast group) was similar to that of the control group. We found that the ratio of spleen interferon-gamma(+)CD4(+) cell/interleukin (IL)-4(+)CD4(+) cell was higher in the mixture and yeast groups than the control group. The number of spleen CD80(+)CD11b(+) cells was significantly lower in the mixture and yeast groups than the control group. In contrast, the numbers of spleen CD122(+)CD8 alpha(+) and IL-10(+)CD4(+) cells were significantly higher in the mixture group than the control and yeast groups while the numbers of IgE(+)B220(+) and Fc epsilon RI alpha(+)CD117(+) cells were significantly lower in the mixture group. These results suggested that the mixture of S. cerevisiae and its specific goat's milk IgG-rich fraction reduced OVA-induced allergic symptoms in BALB/c mice via the induction of suppressor T cells and the reduction of Ig E-producing cells and high affinity IgE receptor-positive mast cells rather than the adjustment of the Th1/Th2 balance.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ ISSN
収録物識別子 0026-3788
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00285427
著者版フラグ
値 publisher
WoS
Web of Science
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000287643600002
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