{"_buckets": {"deposit": "04edccd1-2d0e-4c46-9b3b-75282a8f7a83"}, "_deposit": {"id": "10308", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "10308"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00010308", "sets": ["1016:1017"]}, "author_link": ["32621", "32622", "32623"], "control_number": "10308", "item_1628147817048": {"attribute_name": "\u51fa\u7248\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_6_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2010-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "445", "bibliographicPageStart": "441", "bibliographicVolumeNumber": "56", "bibliographic_titles": [{"bibliographic_title": "JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY"}]}]}, "item_6_description_20": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "We investigated the effect of Lactobacillus crispatus KT-11 (KT-11) on intestinal immune systems in C3H/HeN mice. The level of intestinal total immunoglobulin (Ig) A was significantly higher in mice given KT-11 than in mice not given KT-11. Gene expression relating to antibody production and innate immune response increased more than 2-fold in the former compared with the later. Moreover, the number of IL-6(+)C11b(+) cells was significantly higher in Peyer\u0027s patch cells cultured with KT-11 than in those cultured without KT-11, although the number of CD4(+) cells and the cell ratio of CD4(+)/CD8(+) were remarkably lower in the culture with KT-11. These results indicate that KT-11 enhances intestinal IgA production and innate immune response in C3H/HeN mice.", "subitem_description_type": "Abstract"}]}, "item_6_description_30": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7\uff08\u30b3\u30f3\u30c6\u30f3\u30c4\u306e\u7a2e\u985e\uff09", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_31": {"attribute_name": "\u30d5\u30a9\u30fc\u30de\u30c3\u30c8\uff1amime\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "\u5f15\u7528", "attribute_value_mlt": [{"subitem_description": "JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY. 56(6): 441-445(2010)", "subitem_description_type": "Other"}]}, "item_6_publisher_4": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "CENTER ACADEMIC PUBL JAPAN"}]}, "item_6_relation_46": 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"0301-4800", "subitem_source_identifier_type": "PISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0301-4800", "subitem_source_identifier_type": "PISSN"}]}, "item_6_source_id_40": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00703822", "subitem_source_identifier_type": "NCID"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Tobita,  Keisuke"}], "nameIdentifiers": [{"nameIdentifier": "32621", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yanaka,  Hiroyuki"}], "nameIdentifiers": [{"nameIdentifier": "32622", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Otani,  Hajime"}], "nameIdentifiers": [{"nameIdentifier": "32623", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-25"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Lactobacillus_crispatus_KT-11_Enhances.pdf", "filesize": [{"value": "118.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 118300.0, "url": {"label": "Lactobacillus_crispatus_KT-11_Enhances.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/10308/files/Lactobacillus_crispatus_KT-11_Enhances.pdf"}, "version_id": "00a41aea-2899-4256-8f30-f308e34a1eb4"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Lactobacillus crispatus KT-11", "subitem_subject_scheme": "Other"}, {"subitem_subject": "immunoglobulin A", "subitem_subject_scheme": "Other"}, {"subitem_subject": "innate immune system", "subitem_subject_scheme": "Other"}, {"subitem_subject": "C3H/HeN mouse", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Peyer\u0027s patch", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Lactobacillus crispatus KT-11 Enhances Intestinal Immune Functions in C3H/HeN Mice", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Lactobacillus crispatus KT-11 Enhances Intestinal Immune Functions in C3H/HeN Mice", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["1016/1017"], "permalink_uri": "http://hdl.handle.net/10091/13189", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2011-06-20"}, "publish_date": "2011-06-20", "publish_status": "0", "recid": "10308", "relation": {}, "relation_version_is_last": true, "title": ["Lactobacillus crispatus KT-11 Enhances Intestinal Immune Functions in C3H/HeN Mice"], "weko_shared_id": -1}