Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2011-06-20 |
タイトル |
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タイトル |
Lactobacillus crispatus KT-11 Enhances Intestinal Immune Functions in C3H/HeN Mice |
言語 |
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言語 |
eng |
DOI |
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関連タイプ |
isIdenticalTo |
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関連識別子 |
https://doi.org/10.3177/jnsv.56.441 |
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関連名称 |
10.3177/jnsv.56.441 |
キーワード |
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主題 |
Lactobacillus crispatus KT-11, immunoglobulin A, innate immune system, C3H/HeN mouse, Peyer's patch |
資源タイプ |
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資源 |
http://purl.org/coar/resource_type/c_6501 |
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タイプ |
journal article |
著者 |
Tobita, Keisuke
Yanaka, Hiroyuki
Otani, Hajime
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出版者 |
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出版者 |
CENTER ACADEMIC PUBL JAPAN |
引用 |
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内容記述 |
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY. 56(6): 441-445(2010) |
書誌情報 |
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
巻 56,
号 6,
p. 441-445,
発行日 2010-12
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抄録 |
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内容記述 |
We investigated the effect of Lactobacillus crispatus KT-11 (KT-11) on intestinal immune systems in C3H/HeN mice. The level of intestinal total immunoglobulin (Ig) A was significantly higher in mice given KT-11 than in mice not given KT-11. Gene expression relating to antibody production and innate immune response increased more than 2-fold in the former compared with the later. Moreover, the number of IL-6(+)C11b(+) cells was significantly higher in Peyer's patch cells cultured with KT-11 than in those cultured without KT-11, although the number of CD4(+) cells and the cell ratio of CD4(+)/CD8(+) were remarkably lower in the culture with KT-11. These results indicate that KT-11 enhances intestinal IgA production and innate immune response in C3H/HeN mice. |
資源タイプ(コンテンツの種類) |
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内容記述 |
Article |
ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0301-4800 |
書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA00703822 |
他の資源との関係:URI |
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関連名称 |
10.3177/jnsv.56.441 |
権利 |
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権利情報 |
Copyright (c) 2011 by the Center for Academic Publications Japan |
権利 |
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権利情報 |
日本ビタミン学会, 日本栄養・食糧学会 |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |