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Anti-allergic effects of Lactobacillus crispatus KT-11 strain on ovalbumin-sensitized BALB/c mice
http://hdl.handle.net/10091/13179
http://hdl.handle.net/10091/131794397b5c4-a1dc-4638-bb0d-b2a323948025
| 名前 / ファイル | ライセンス | アクション |
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Anti-allergic_effects_Lactobacillus_crispatus.pdf (306.7 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||
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| 公開日 | 2011-06-20 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Anti-allergic effects of Lactobacillus crispatus KT-11 strain on ovalbumin-sensitized BALB/c mice | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| DOI | ||||||||||||
| 関連識別子 | https://doi.org/10.1111/j.1740-0929.2010.00795.x | |||||||||||
| 関連名称 | 10.1111/j.1740-0929.2010.00795.x | |||||||||||
| キーワード | ||||||||||||
| 主題 | anti-allergic effect, antigen-presenting cells, Lactobacillus crispatus KT-11, mast cells, Th1, Th2 balance | |||||||||||
| 資源タイプ | ||||||||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| タイプ | journal article | |||||||||||
| 著者 |
Tobita, Keisuke
× Tobita, Keisuke
× Yanaka, Hiroyuki
× Otani, Hajime
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| 出版者 | ||||||||||||
| 出版者 | Blackwell Publishing | |||||||||||
| 引用 | ||||||||||||
| 内容記述 | ANIMAL SCIENCE JOURNAL. 81(6):699-705 (2010) | |||||||||||
| 書誌情報 |
ANIMAL SCIENCE JOURNAL 巻 81, 号 6, p. 699-705, 発行日 2010-12 |
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| 内容記述 | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | The definitive version is available at www.blackwell-synergy.com | |||||||||||
| 抄録 | ||||||||||||
| 内容記述 | In this study, we investigated the effects of oral ingestion of Lactobacillus crispatus KT-11 strain (KT-11) on the immune response in an allergic rhinitis mouse model, ovalbumin (OVA)-sensitized BALB/c mice. Sneezing activity in mice that were administered a KT-11-supplemented diet was significantly lower than that in mice administered a KT-11-free diet (control diet) at age 11 weeks. We found that serum OVA-specific immunoglobulin E (IgE) levels and total number of interleukin (IL)-4+CD4+ spleen cells in mice that were administered a KT-11-supplemented diet were significantly lower than in mice administered a control diet. The ratio of spleen interferon-gamma+CD4+/IL-4+CD4+ cells was higher in the mice administered the KT-11-supplemented diet compared to that in mice administered the control or L. rhamnosus GG-supplemented diet. In contrast, the number of CD11b+CD80+ and Fc epsilon RI alpha+CD117+ cells was significantly lower in mice administered the KT-11-supplemented diet. These results suggested that KT-11 reduced OVA-induced allergic symptoms in BALB/c mice via the adjustment of the T helper type 1/T helper type 2 balance, and a decrease in the number of antigen-presenting cells and high affinity IgE receptor-positive mast cells. | |||||||||||
| 資源タイプ（コンテンツの種類） | ||||||||||||
| ISSN | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 1344-3941 | |||||||||||
| 書誌レコードID | ||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||
| 収録物識別子 | AA11677214 | |||||||||||
| PubMed | ||||||||||||
| 識別子タイプ | PMID | |||||||||||
| 関連識別子 | https://pubmed.ncbi.nlm.nih.gov/21108691/ | |||||||||||
| 関連名称 | 21108691 | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | AM | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||
| WoS | ||||||||||||
| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000284643800012 | |||||||||||
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Tobita, Keisuke, Yanaka, Hiroyuki, Otani, Hajime, 2010, Anti-allergic effects of Lactobacillus crispatus KT-11 strain on ovalbumin-sensitized BALB/c mice: Blackwell Publishing, 699–705 p.
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