{"_buckets": {"deposit": "7a10eedd-2577-4709-a436-d298483b3b5b"}, "_deposit": {"id": "10598", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "10598"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00010598", "sets": []}, "author_link": ["33491", "33492", "33493"], "item_1628147817048": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_6_alternative_title_1": {"attribute_name": "その他（別言語等）のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "ペプチド合成またはＺ(ベンジルオキシカルボニル） : アミノ酸エステル加水分解における２，３のプロテアーゼの微環境へのｎ-アルコール効果の多様性", "subitem_alternative_title_language": "ja"}]}, "item_6_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1995-12-31", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1-2", "bibliographicPageEnd": "22", "bibliographicPageStart": "15", "bibliographicVolumeNumber": "32", "bibliographic_titles": [{"bibliographic_title": "信州大学農学部紀要"}]}]}, "item_6_description_20": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "To investigate the interaction of proteases (thermolysin, α-chymotrypsin, papain and pepsin) with organic solvent molecules, buffer systems in which n-alcohols were dissolved as to make a one-phase medium were used in the case of peptide synthesis or Z-amino acid hydrolysis as model reactions. The chain length of n-alcohols gave different characteristics of the effective patterns to the enzymes, and also each protease was affected in different modes of effective profiles by n-alcohols. Activity of α-chymotrypsin was increased by n-alcohols higher than n-hexanol grdually with increase of their concentration just over the saturation to the buffer. The activation was proposed to be non-essential by kinetics. Meanwhile, n-pentanol to α-chymotrypsin showed to be an uncompetitive inhibitor.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_6_description_30": {"attribute_name": "資源タイプ（コンテンツの種類）", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_31": {"attribute_name": "フォーマット：mimeタイプ", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "信州大学農学部紀要. 32(1-2): 15-22 (1995)", "subitem_description_type": "Other"}]}, "item_6_publisher_4": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "信州大学農学部"}]}, "item_6_select_64": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_6_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0583-0621", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0583-0621", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_40": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00121352", "subitem_source_identifier_type": "NCID"}]}, "item_6_text_66": {"attribute_name": "sortkey", "attribute_value_mlt": [{"subitem_text_value": "03"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Sato,  K"}], "nameIdentifiers": [{"nameIdentifier": "33491", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tadasa,  K"}], "nameIdentifiers": [{"nameIdentifier": "33492", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kayahara,  H"}], "nameIdentifiers": [{"nameIdentifier": "33493", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-25"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "v32_03.pdf", "filesize": [{"value": "345.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 345300.0, "url": {"label": "v32_03.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/10598/files/v32_03.pdf"}, "version_id": "de454218-236c-4e60-99b5-dc7e5cbf405b"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "protease", "subitem_subject_scheme": "Other"}, {"subitem_subject": "microenvironment", "subitem_subject_scheme": "Other"}, {"subitem_subject": "thermolysin", "subitem_subject_scheme": "Other"}, {"subitem_subject": "α-chymotrypsin", "subitem_subject_scheme": "Other"}, {"subitem_subject": "papain", "subitem_subject_scheme": "Other"}, {"subitem_subject": "pepsin", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Variety of Effect of n-Alcohols on Microenvironment of Some Proteases in Peptide Synthesis or Z (N-Benzyloxycarbonyl) : Amino Acid Ester Hydrolysis", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Variety of Effect of n-Alcohols on Microenvironment of Some Proteases in Peptide Synthesis or Z (N-Benzyloxycarbonyl) : Amino Acid Ester Hydrolysis", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["1039"], "permalink_uri": "http://hdl.handle.net/10091/845", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2007-12-28"}, "publish_date": "2007-12-28", "publish_status": "0", "recid": "10598", "relation": {}, "relation_version_is_last": true, "title": ["Variety of Effect of n-Alcohols on Microenvironment of Some Proteases in Peptide Synthesis or Z (N-Benzyloxycarbonyl) : Amino Acid Ester Hydrolysis"], "weko_shared_id": -1}