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高血圧自然発症ラット(SHR)およびWistar系ラットの長期高地環境暴露による心肥大に対するVerapamilの効果
http://hdl.handle.net/10091/12741
http://hdl.handle.net/10091/127413cf06ac4-382b-4226-beef-357cb08f1b71
名前 / ファイル | ライセンス | アクション |
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Item type | 研究報告書 / Research Paper(1) | |||||
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公開日 | 2011-04-20 | |||||
タイトル | ||||||
言語 | ja | |||||
タイトル | 高血圧自然発症ラット(SHR)およびWistar系ラットの長期高地環境暴露による心肥大に対するVerapamilの効果 | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_18ws | |||||
タイプ | research report | |||||
その他(別言語等)のタイトル | ||||||
その他のタイトル | The Effect of Ca2+ Antagonist Verapamil on Right Ventricular Hypetrophy of Spontaneously Hypertensive Rats (SBR) and Wistar Rats Exposed at Bigh Altitude | |||||
著者 |
小林, 俊夫
× 小林, 俊夫× 矢崎, 久美× 吉村, 一彦× 福島, 雅夫× 久保, 恵嗣× 半田, 健次郎× 草間, 昌三× 酒井, 秋男× 上田, 五雨 |
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出版者 | ||||||
出版者 | 信州大学環境問題研究教育懇談会 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 信州大学環境科学論集6:101-103(1984) | |||||
書誌情報 |
信州大学環境科学論集 巻 6, p. 101-103, 発行日 1984-03-31 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We studied the effect of Ca2十antagonistverapamil(V) on right ventricular hypertrophy exposed at high altitude. Male Wistar rats(WR) of an initial weight of 118.2 6.5g(n=48) and spontaneously hypertensive rats(SHR) of initial weight of 83.2士8.0g(n=48) were used. They were divided into four groups. Each group consists of WR(n=12) and SHR(n =12). The first and second groups were taken to a high altitude station(2,400m),w here they were kept for 60 days. The rats in the first group were given a dietcontaining 125mgjkg of V. The second received no treatment. The rats in the third group treated by Vand in the non-treated fourth group were kept at a laboratory altitude (640m). Mter 60 days of treatment,they were killed,a nd the right ventricular weight(RW) and the weight of the left ventricle plus the septum(LW) were determined. In rats in the first and second groups,ch ronic treatment with V increased RWa nd reduced LW . The ratio of RW to LW in rats with treatment with V were higher values. There was no significant difference in the ratio of RW to LW between WR and SHR in the first and second groups. These findings suggested that the effect of V treatment were not seen on right ventricular hypertrophy of rats exposed at high altitude | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0915-7492 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10562285 | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |