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Methods During surgical prostate resection of 32 BPO patients, mucosal biopsies were collected and analyzed by reverse transcriptase polymerase chain reaction to determine the expression level of beta 3-AR mRNA. First desire to void (FDV) and strong desire to void (SDV), detrusor overactivity (DO), and bladder outlet obstruction (BOO) were measured pre-operatively. Patients with FDVs?\u003c?200?ml or SDVs?\u003c?300?ml were assigned to the small capacity group (n?=?19). Patients with FDVs?\u003e?201?ml and SDVs?\u003e?301?ml were assigned to the large capacity group (n?=?13). The same patients with positive DO were also assigned to the DO+ group (n?=?11), and those with negative DO were assigned to the DO- group (n?=?21). Finally, patients whose position on the Schafer nomogram was greater than degree V were assigned to the severe BOO group (n?=?17), while those with less than degree IV were assigned to the mild BOO group (n?=?15). 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  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

Relationship between expression of ss 3-adrenoceptor mRNA in bladder mucosa and urodynamic findings in men with lower urinary tract symptoms

http://hdl.handle.net/10091/00019831
d3ee60a8-0098-465b-b1e0-4bc56096deb6
名前 / ファイル ライセンス アクション
Relationship_expression_ss_3-adrenoceptor_mRNA_bladder_mucosa_urodynamic_findings.pdf Relationship_expression_ss_3-adrenoceptor_mRNA_bladder_mucosa_urodynamic_findings.pdf (406.8 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2017-09-20
タイトル
言語 en
タイトル Relationship between expression of ss 3-adrenoceptor mRNA in bladder mucosa and urodynamic findings in men with lower urinary tract symptoms
言語
言語 eng
キーワード
主題Scheme Other
主題 ss 3-adrenoceptor
キーワード
主題Scheme Other
主題 benign prostatic hyperplasia
キーワード
主題Scheme Other
主題 bladder urothelium
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Kurizaki, Yoshiki

× Kurizaki, Yoshiki

WEKO 104031

en Kurizaki, Yoshiki

Search repository
Ishizuka, Osamu

× Ishizuka, Osamu

WEKO 104032

en Ishizuka, Osamu

Search repository
Imamura, Tetsuya

× Imamura, Tetsuya

WEKO 104033

en Imamura, Tetsuya

Search repository
Ishikawa, Masakuni

× Ishikawa, Masakuni

WEKO 104034

en Ishikawa, Masakuni

Search repository
Ichino, Midori

× Ichino, Midori

WEKO 104035

en Ichino, Midori

Search repository
Ogawa, Teruyuki

× Ogawa, Teruyuki

WEKO 104036

en Ogawa, Teruyuki

Search repository
Nishizawa, Osamu

× Nishizawa, Osamu

WEKO 104037

en Nishizawa, Osamu

Search repository
Andersson, Karl-Erik

× Andersson, Karl-Erik

WEKO 104038

en Andersson, Karl-Erik

Search repository
信州大学研究者総覧へのリンク
氏名 Ishizuka, Osamu
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.gmfaHekh.html
信州大学研究者総覧へのリンク
氏名 Imamura, Tetsuya
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.ypACOmyC.html
信州大学研究者総覧へのリンク
氏名 Ogawa, Teruyuki
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.yhTUgpkh.html
信州大学研究者総覧へのリンク
氏名 Nishizawa, Osamu
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.WeyeWmyU.html
出版者
出版者 WILEY-BLACKWELL
引用
内容記述タイプ Other
内容記述 NEUROUROLOGY AND URODYNAMICS. 32(1):88-91 (2013)
書誌情報 NEUROUROLOGY AND URODYNAMICS

巻 32, 号 1, p. 88-91, 発行日 2013-01
抄録
内容記述タイプ Abstract
内容記述 Aims To investigate the relationship between urinary bladder mucosal expression of beta 3-adrenoceptor (AR) mRNA and urodynamic findings in patients with lower urinary tract symptoms and benign prostatic obstruction (BPO). Methods During surgical prostate resection of 32 BPO patients, mucosal biopsies were collected and analyzed by reverse transcriptase polymerase chain reaction to determine the expression level of beta 3-AR mRNA. First desire to void (FDV) and strong desire to void (SDV), detrusor overactivity (DO), and bladder outlet obstruction (BOO) were measured pre-operatively. Patients with FDVs?<?200?ml or SDVs?<?300?ml were assigned to the small capacity group (n?=?19). Patients with FDVs?>?201?ml and SDVs?>?301?ml were assigned to the large capacity group (n?=?13). The same patients with positive DO were also assigned to the DO+ group (n?=?11), and those with negative DO were assigned to the DO- group (n?=?21). Finally, patients whose position on the Schafer nomogram was greater than degree V were assigned to the severe BOO group (n?=?17), while those with less than degree IV were assigned to the mild BOO group (n?=?15). Results The expression level of beta 3-AR mRNA was similar in both bladder capacity groups and both DO groups. However, the expression level in the severe BOO group was significantly less than in the mild BOO group (P?=?0.043). Conclusions The expression of bladder mucosal beta 3-AR mRNA was significantly decreased in patients with severe BOO, suggesting that beta 3-ARs might be affected by the degree of BOO. Neurourol. Urodynam. 32: 8891, 2013. (c) 2012 Wiley Periodicals, Inc.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 0733-2467
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA10631557
PubMed
関連識別子
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/22692629
関連名称
関連名称 22692629
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1002/nau.22278
関連名称
関連名称 10.1002/nau.22278
権利
権利情報 This is the peer reviewed version of the following article: Kurizaki, Y., Ishizuka, O., Imamura, T., Ishikawa, M., Ichino, M., Ogawa, T., Nishizawa, O. and Andersson, K.-E. (2013), Relationship between expression of β3-adrenoceptor mRNA in bladder mucosa and urodynamic findings in men with lower urinary tract symptoms. Neurourol. Urodyn., 32: 88–91, which has been published in final form at https://doi.org/10.1002/nau.22278 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000312726200017
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