| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-09-20 |
| タイトル |
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タイトル |
Relationship between expression of ss 3-adrenoceptor mRNA in bladder mucosa and urodynamic findings in men with lower urinary tract symptoms |
| 言語 |
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言語 |
eng |
| DOI |
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関連識別子 |
https://doi.org/10.1002/nau.22278 |
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関連名称 |
10.1002/nau.22278 |
| キーワード |
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主題 |
ss 3-adrenoceptor, benign prostatic hyperplasia, bladder urothelium |
| 資源タイプ |
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資源 |
http://purl.org/coar/resource_type/c_6501 |
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タイプ |
journal article |
| 著者 |
Kurizaki, Yoshiki
Ishizuka, Osamu
Imamura, Tetsuya
Ishikawa, Masakuni
Ichino, Midori
Ogawa, Teruyuki
Nishizawa, Osamu
Andersson, Karl-Erik
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| 信州大学研究者総覧へのリンク |
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氏名 |
Ishizuka, Osamu |
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URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.gmfaHekh.html |
| 信州大学研究者総覧へのリンク |
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氏名 |
Imamura, Tetsuya |
|
URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.ypACOmyC.html |
| 信州大学研究者総覧へのリンク |
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氏名 |
Ogawa, Teruyuki |
|
URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.yhTUgpkh.html |
| 信州大学研究者総覧へのリンク |
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氏名 |
Nishizawa, Osamu |
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URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.WeyeWmyU.html |
| 出版者 |
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出版者 |
WILEY-BLACKWELL |
| 引用 |
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内容記述 |
NEUROUROLOGY AND URODYNAMICS. 32(1):88-91 (2013) |
| 書誌情報 |
NEUROUROLOGY AND URODYNAMICS
巻 32,
号 1,
p. 88-91,
発行日 2013-01
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| 抄録 |
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内容記述 |
Aims To investigate the relationship between urinary bladder mucosal expression of beta 3-adrenoceptor (AR) mRNA and urodynamic findings in patients with lower urinary tract symptoms and benign prostatic obstruction (BPO). Methods During surgical prostate resection of 32 BPO patients, mucosal biopsies were collected and analyzed by reverse transcriptase polymerase chain reaction to determine the expression level of beta 3-AR mRNA. First desire to void (FDV) and strong desire to void (SDV), detrusor overactivity (DO), and bladder outlet obstruction (BOO) were measured pre-operatively. Patients with FDVs?<?200?ml or SDVs?<?300?ml were assigned to the small capacity group (n?=?19). Patients with FDVs?>?201?ml and SDVs?>?301?ml were assigned to the large capacity group (n?=?13). The same patients with positive DO were also assigned to the DO+ group (n?=?11), and those with negative DO were assigned to the DO- group (n?=?21). Finally, patients whose position on the Schafer nomogram was greater than degree V were assigned to the severe BOO group (n?=?17), while those with less than degree IV were assigned to the mild BOO group (n?=?15). Results The expression level of beta 3-AR mRNA was similar in both bladder capacity groups and both DO groups. However, the expression level in the severe BOO group was significantly less than in the mild BOO group (P?=?0.043). Conclusions The expression of bladder mucosal beta 3-AR mRNA was significantly decreased in patients with severe BOO, suggesting that beta 3-ARs might be affected by the degree of BOO. Neurourol. Urodynam. 32: 8891, 2013. (c) 2012 Wiley Periodicals, Inc. |
| 資源タイプ（コンテンツの種類） |
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| ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0733-2467 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA10631557 |
| PubMed |
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識別子タイプ |
PMID |
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関連識別子 |
https://pubmed.ncbi.nlm.nih.gov/22692629 |
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関連名称 |
22692629 |
| 権利 |
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権利情報 |
This is the peer reviewed version of the following article: Kurizaki, Y., Ishizuka, O., Imamura, T., Ishikawa, M., Ichino, M., Ogawa, T., Nishizawa, O. and Andersson, K.-E. (2013), Relationship between expression of β3-adrenoceptor mRNA in bladder mucosa and urodynamic findings in men with lower urinary tract symptoms. Neurourol. Urodyn., 32: 88–91, which has been published in final form at https://doi.org/10.1002/nau.22278 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. |
| 出版タイプ |
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出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| WoS |
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URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000312726200017 |
Relationship_expression_ss_3-adrenoceptor_mRNA_bladder_mucosa_urodynamic_findings.pdf (406.8 kB)
