{"_buckets": {"deposit": "e0bb250f-0367-45a5-83ed-bc0a2bfce487"}, "_deposit": {"id": "20088", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "20088"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00020088"}, "item_6_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2014-05-07", "bibliographicIssueDateType": "Issued"}, "bibliographicPageStart": "649185", "bibliographicVolumeNumber": "2014", "bibliographic_titles": [{"bibliographic_title": "BIOMED RESEARCH INTERNATIONAL"}]}]}, "item_6_description_20": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Background. Soluble lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) level is a novel biomarker for diagnosis of acute coronary syndrome (ACS); however, this level in the coronary circulation has yet to be examined. Methods. Twenty-seven consecutive patients with ACS and 40 patients with effort angina pectoris (EAP) undergoing percutaneous coronary intervention (PCI) had levels of soluble LOX-1 and LOX-1 index measured in paired blood samples from aorta (Ao) and coronary sinus (CS) just prior to the PCI. Results.We found positive correlations between soluble LOX-1 levels in the Ao and CS in both ACS and EAP patients (????P \u003c 0.01, for both). The soluble LOX-1 levels in the Ao and CS were higher in ACS than in EAP patients (????P \u003c 0.01, for both).The levels of soluble LOX-1 and LOX-1 index of the CS were significantly greater than those of the Ao in both ACS and EAP patients (????P \u003c 0.01, for both). Receiver operating characteristic curves for ACS detection demonstrated high sensitivity and specificity for the solubleLOX-1 andLOX-1 indexwith no differences between theAo andCS. Conclusions.Thepresent study showed that circulating soluble LOX-1 originates from coronary circulation and soluble LOX-1 and LOX-1 index are useful biomarkers for ACS.", "subitem_description_type": "Abstract"}]}, "item_6_description_30": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7\uff08\u30b3\u30f3\u30c6\u30f3\u30c4\u306e\u7a2e\u985e\uff09", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "\u5f15\u7528", "attribute_value_mlt": [{"subitem_description": "BIOMED RESEARCH INTERNATIONAL.2014:649185(2014)", "subitem_description_type": "Other"}]}, "item_6_link_3": {"attribute_name": "\u4fe1\u5dde\u5927\u5b66\u7814\u7a76\u8005\u7dcf\u89a7\u3078\u306e\u30ea\u30f3\u30af", "attribute_value_mlt": [{"subitem_link_text": "Sawamura, Tatsuya", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.HafpjeAF.html"}]}, "item_6_link_67": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=7\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000336166000001"}]}, "item_6_publisher_4": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "HINDAWI PUBLISHING CORPORATION"}]}, "item_6_relation_48": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1155/2014/649185"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1155/2014/649185", "subitem_relation_type_select": "DOI"}}]}, "item_6_rights_62": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "\u00a9 2014 Tomofumi Misaka et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited."}]}, "item_6_select_64": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_6_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2314-6133", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2314-6133", "subitem_source_identifier_type": "ISSN"}]}, "item_6_text_70": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "LOW-DENSITY-LIPOPROTEIN; MYOCARDIAL-INFARCTION; HEART-DISEASE; INFLAMMATION; MARKERS; LOX-1; SEGMENT; LESIONS"}]}, "item_6_textarea_68": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "Background. Soluble lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) level is a novel biomarker for diagnosis of acute coronary syndrome (ACS); however, this level in the coronary circulation has yet to be examined. Methods. Twenty-seven consecutive patients with ACS and 40 patients with effort angina pectoris (EAP) undergoing percutaneous coronary intervention (PCI) had levels of soluble LOX-1 and LOX-1 index measured in paired blood samples from aorta (Ao) and coronary sinus (CS) just prior to the PCI. Results. We found positive correlations between soluble LOX-1 levels in the Ao and CS in both ACS and EAP patients (P \u003c 0.01, for both). The soluble LOX-1 levels in the Ao and CS were higher in ACS than in EAP patients (P \u003c 0.01, for both). The levels of soluble LOX-1 and LOX-1 index of the CS were significantly greater than those of the Ao in both ACS and EAP patients (P \u003c 0.01, for both). Receiver operating characteristic curves for ACS detection demonstrated high sensitivity and specificity for the soluble LOX-1 andLOX-1 index with no differences between the Ao and CS. Conclusions. The present study showed that circulating soluble LOX-1 originates from coronary circulation and soluble LOX-1 and LOX-1 index are useful biomarkers for ACS."}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Misaka, T"}], "nameIdentifiers": [{"nameIdentifier": "106223", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suzuki, S"}], "nameIdentifiers": [{"nameIdentifier": "106224", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sakamoto, N"}], "nameIdentifiers": [{"nameIdentifier": "106225", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamaki, T"}], "nameIdentifiers": [{"nameIdentifier": "106226", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sugimoto, K"}], "nameIdentifiers": [{"nameIdentifier": "106227", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kunii, H"}], "nameIdentifiers": [{"nameIdentifier": "106228", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakazato, K"}], "nameIdentifiers": [{"nameIdentifier": "106229", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Saitoh, S"}], "nameIdentifiers": [{"nameIdentifier": "106230", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sawamura, T"}], "nameIdentifiers": [{"nameIdentifier": "106231", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishibashi, T"}], "nameIdentifiers": [{"nameIdentifier": "106232", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takeishi, Y"}], "nameIdentifiers": [{"nameIdentifier": "106233", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-09-12"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "25293063_17.pdf", "filesize": [{"value": "1.8 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "\u00a9 2014 Tomofumi Misaka et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.", "licensetype": "license_free", "mimetype": "application/pdf", "size": 1800000.0, "url": {"label": "25293063_17.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/20088/files/25293063_17.pdf"}, "version_id": "ebbacd1a-f833-452c-9b6a-49ee8dd1587b"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Significance of Soluble Lectin-Like Oxidized LDL Receptor-1 Levels in Systemic and Coronary Circulation in Acute Coronary Syndrome", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Significance of Soluble Lectin-Like Oxidized LDL Receptor-1 Levels in Systemic and Coronary Circulation in Acute Coronary Syndrome"}]}, "item_type_id": "6", "owner": "1", "path": ["461/462"], "permalink_uri": "http://hdl.handle.net/10091/00020849", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2018-09-12"}, "publish_date": "2018-09-12", "publish_status": "0", "recid": "20088", "relation": {}, "relation_version_is_last": true, "title": ["Significance of Soluble Lectin-Like Oxidized LDL Receptor-1 Levels in Systemic and Coronary Circulation in Acute Coronary Syndrome"], "weko_shared_id": null}