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Genetic Contribution to the Pathogenesis of Primary Biliary Cholangitis
http://hdl.handle.net/10091/00020994
http://hdl.handle.net/10091/0002099450e640b4-8b85-4d15-8266-7e162e4f3290
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-10-31 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Genetic Contribution to the Pathogenesis of Primary Biliary Cholangitis | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Joshita, Satoru
× Joshita, Satoru× Umemura, Takeji× Tanaka, Eiji× Ota, Masao |
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信州大学研究者総覧へのリンク | ||||||
氏名 | Umemura, Takeji | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.ymSpgpkh.html | |||||
出版者 | ||||||
出版者 | HINDAWI LTD | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | JOURNAL OF IMMUNOLOGY RESEARCH. :3073504(2017) | |||||
書誌情報 |
JOURNAL OF IMMUNOLOGY RESEARCH p. 3073504, 発行日 2017-02-01 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Formerly termed primary biliary cirrhosis, primary biliary cholangitis (PBC) is a chronic and progressive cholestatic liver disease characterized by the presence of antimitochondrial antibodies. Ursodeoxycholic acid (UDCA) therapy is the most effective and approved treatment for PBC and leads to a favorable outcome in the vast majority of cases. Although the etiology of PBC has not yet been elucidated, human leukocyte antigen (HLA) class II alleles have been consistently associated with disease onset for decades. Individuals in different geographic regions of the world may have varying susceptibility alleles that reflect indigenous triggering antigens. In this review, we describe the influence of HLA alleles and other gene polymorphisms on PBC along with the results of genome-wide association studies (GWAS) on this disease. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 2314-8861 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1155/2017/3073504 | |||||
関連名称 | 10.1155/2017/3073504 | |||||
権利 | ||||||
権利情報 | © 2017 Satoru Joshita et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000394871600001 |