| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2019-05-08 |
| タイトル |
|
|
タイトル |
Toll -like receptor ligand-dependent inflammatory responses in chick skeletal muscle myoblasts |
| 言語 |
|
|
言語 |
eng |
| DOI |
|
|
|
関連識別子 |
https://doi.org/10.1016/j.dci.2018.10.013 |
|
|
関連名称 |
10.1016/j.dci.2018.10.013 |
| キーワード |
|
|
主題 |
Inflammatory response, Interleukin, Skeletal muscle myoblast, Toll-like receptor |
| 資源タイプ |
|
|
資源 |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 著者 |
Nihashi, Yuma
Ono, Tamao
Kagami, Hiroshi
Takaya, Tomohide
|
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Ono, Tamao |
|
URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.WFfCPpkh.html |
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Kagami, Hiroshi |
|
URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.OeyUPUkh.html |
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Takaya, Tomohide |
|
URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.yUcePUkh.html |
| 出版者 |
|
|
出版者 |
ELSEVIER SCI LTD |
| 引用 |
|
|
内容記述 |
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 91:115-122 (2019) |
| 書誌情報 |
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
巻 91,
p. 115-122,
発行日 2019-02
|
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Epub 2018 Oct 30 |
| 抄録 |
|
|
内容記述 |
Toll-like receptors (TLRs) are a group of sensory receptors which are capable of recognizing a microbial invasion and activating innate immune system responses, including inflammatory responses, in both immune and non immune cells. However, TLR functions in chick myoblasts, which are myogenic precursor cells contributing to skeletal muscle development and growth, have not been studied. Here, we report the expression patterns of TLR genes as well as TLR ligand-dependent transcriptions of interleukin (IL) genes in primary-cultured chick myoblasts. Almost TLR genes were expressed both in layer and broiler myoblasts but TLR1A was detected only in embryonic layer chick myoblasts. Chick TLR1/2 ligands, Pam(3)CSK(4) and FSL-1, induced inflammatory ILs in both layer and broiler myoblasts but a TLR4 ligand, lipopolysaccharide, scarcely promoted. This is the first report on TLR ligand-dependent inflammatory responses in chick myoblasts, which may provide useful information to chicken breeding and meat production industries. |
| 資源タイプ（コンテンツの種類） |
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0145-305X |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00627870 |
| PubMed |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
https://pubmed.ncbi.nlm.nih.gov/30389519/ |
|
|
関連名称 |
30389519 |
| 権利 |
|
|
権利情報 |
© 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| WoS |
|
|
URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000451492900013 |
2019_DevCompImmunol_Nihashi_SOAR.pdf (1.4 MB)
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