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  1. 070 農学部, 大学院農学研究科
  2. 0701 学術論文

Berberine and palmatine inhibit the growth of human rhabdomyosarcoma cells

http://hdl.handle.net/10091/00021784
509a02b0-35db-4e62-9b04-d39bc21e838d
名前 / ファイル ライセンス アクション
2020_BBB_Shinji_SOAR.pdf 2020_BBB_Shinji_SOAR.pdf (2.3 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2019-12-05
タイトル
言語 en
タイトル Berberine and palmatine inhibit the growth of human rhabdomyosarcoma cells
言語
言語 eng
キーワード
主題Scheme Other
主題 Berberine
キーワード
主題Scheme Other
主題 palmatine
キーワード
主題Scheme Other
主題 rhabdomyosarcoma
キーワード
主題Scheme Other
主題 three-dimensional culture
キーワード
主題Scheme Other
主題 tumorsphere
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Shinji, Sayaka

× Shinji, Sayaka

WEKO 108776

Shinji, Sayaka

Search repository
Nakamura, Shunichi

× Nakamura, Shunichi

WEKO 108777

Nakamura, Shunichi

Search repository
Nihashi, Yuma

× Nihashi, Yuma

WEKO 108778

Nihashi, Yuma

Search repository
Umezawa, Koji

× Umezawa, Koji

WEKO 108779

Umezawa, Koji

Search repository
Takaya, Tomohide

× Takaya, Tomohide

WEKO 108780

Takaya, Tomohide

Search repository
信州大学研究者総覧へのリンク
氏名 Umezawa, Koji
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.yVcFPhkh.html
信州大学研究者総覧へのリンク
氏名 Takaya, Tomohide
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.yUcePUkh.html
出版者
出版者 TAYLOR & FRANCIS LTD
引用
内容記述タイプ Other
内容記述 BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY. 84(1):63-75 (2020)
書誌情報 BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

巻 84, 号 1, p. 63-75, 発行日 2020
内容記述
内容記述タイプ Other
内容記述 Published online: 29 Aug 2019
抄録
内容記述タイプ Abstract
内容記述 A natural isoquinoline alkaloid, berberine, has been known to exhibit anti-tumor activity in various cancer cells via inducing cell cycle arrest. However, it has not been investigated whether berberine and its analogs inhibit the growth of rhabdomyosarcoma (RMS), which is the most frequent soft tissue tumor in children. The present study examined the anti-tumor effects of berberine and palmatine on expansions of three human embryonal RMS cell lines; ERMS1, KYM1, and RD. Intracellular incorporation of berberine was relatively higher than that of palmatine in every RMS cell line. Berberine significantly inhibited the cell cycle of all RMS cells at G(1) phase. On the other hand, palmatine only suppressed the growth of RD cells. Both of berberine and palmatine strongly inhibited the growth of tumorsphere of RD cells in three-dimensional culture. These results indicate that berberine derivatives have the potential of anti-tumor drugs for RMS therapy.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ ISSN
収録物識別子 0916-8451
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA10824164
PubMed
関連識別子
識別子タイプ PMID
関連識別子 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=31462179
関連名称
関連名称 31462179
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1080/09168451.2019.1659714
関連名称
関連名称 10.1080/09168451.2019.1659714
権利
権利情報 This is an Accepted Manuscript of an article published by Taylor & Francis Group in Bioscience, Biotechnology, and Biochemistry on 2020, available online: https://doi.org/10.1080/09168451.2019.1659714.
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000484642100001
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