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Association of cognitive performance with interleukin-6 receptor Asp358Ala polymorphism in healthy adults
http://hdl.handle.net/10091/17722
http://hdl.handle.net/10091/177224d2a21b7-fa32-439b-ab9a-793eb8d22b30
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-07-23 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Association of cognitive performance with interleukin-6 receptor Asp358Ala polymorphism in healthy adults | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cognitive function | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Interleukin-6 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Genetic polymorphism | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Intelligence | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Sasayama, Daimei
× Sasayama, Daimei× Hori, Hiroaki× Teraishi, Toshiya× Hattori, Kotaro× Ota, Miho× Matsuo, Junko× Kawamoto, Yumiko× Kinoshita, Yukiko× Amano, Naoji× Kunugi, Hiroshi |
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信州大学研究者総覧へのリンク | ||||||
氏名 | Sasayama, Daimei | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.uNkegpkh.html | |||||
出版者 | ||||||
出版者 | SPRINGER WIEN | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | JOURNAL OF NEURAL TRANSMISSION. 119(3):313-318 (2012) | |||||
書誌情報 |
JOURNAL OF NEURAL TRANSMISSION 巻 119, 号 3, p. 313-318, 発行日 2012-03 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Wechsler adult intelligence scale-revised was performed in 576 healthy adults to examine whether a functional polymorphism (Asp358Ala) of the IL-6 receptor (IL-6R) gene is associated with cognitive performance. Verbal intelligence quotient in Asp homozygotes was significantly higher compared to Ala carriers (P = 0.005). Compared to Ala carriers, Asp homozygotes performed better in the verbal subtests requiring long-term memory stores. Elevated IL-6 and soluble IL-6R levels in Ala carriers may have negative impact on acquiring verbal cognitive ability requiring long-term memory. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0300-9564 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11077137 | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | https://pubmed.ncbi.nlm.nih.gov/21879314 | |||||
関連名称 | 21879314 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1007/s00702-011-0709-3 | |||||
関連名称 | 10.1007/s00702-011-0709-3 | |||||
権利 | ||||||
権利情報 | The original publication is available at www.springerlink.com | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000300587900002 |