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  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

Spinocerebellar ataxia type 6 (SCA6): Clinical pilot trial with gabapentin

http://hdl.handle.net/10091/16902
e35b8412-9d39-4112-9a68-abbb498a12a3
名前 / ファイル ライセンス アクション
Spinocerebellar_ataxia_type_6_SCA6.pdf Spinocerebellar_ataxia_type_6_SCA6.pdf (315.2 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2013-04-01
タイトル
言語 en
タイトル Spinocerebellar ataxia type 6 (SCA6): Clinical pilot trial with gabapentin
言語
言語 eng
キーワード
主題Scheme Other
主題 Spinocerebellar ataxia type 6 (SCA6)
キーワード
主題Scheme Other
主題 Gabapentin
キーワード
主題Scheme Other
主題 The International Cooperative Ataxia Rating Scales (ICARS)
キーワード
主題Scheme Other
主題 Voltage-dependent calcium channel (VDCC)
キーワード
主題Scheme Other
主題 gamma-aminobutyric acid (GABA)
キーワード
主題Scheme Other
主題 Postural sway study
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Nakamura, Katsuya

× Nakamura, Katsuya

WEKO 7049

en Nakamura, Katsuya

Search repository
Yoshida, Kunihiro

× Yoshida, Kunihiro

WEKO 7050

en Yoshida, Kunihiro

Search repository
Miyazaki, Daigo

× Miyazaki, Daigo

WEKO 7051

en Miyazaki, Daigo

Search repository
Morita, Hiroshi

× Morita, Hiroshi

WEKO 7052

en Morita, Hiroshi

Search repository
Ikeda, Shu-ichi

× Ikeda, Shu-ichi

WEKO 7053

en Ikeda, Shu-ichi

Search repository
信州大学研究者総覧へのリンク
氏名 Yoshida, Kunihiro
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.yhfNHFkh.html
信州大学研究者総覧へのリンク
氏名 Morita, Hiroshi
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.HUyNHhkh.html
出版者
出版者 ELSEVIER SCIENCE BV
引用
内容記述タイプ Other
内容記述 JOURNAL OF THE NEUROLOGICAL SCIENCES. 278(1-2):107-111 (2009)
書誌情報 JOURNAL OF THE NEUROLOGICAL SCIENCES

巻 278, 号 1-2, p. 107-111, 発行日 2009-03-15
抄録
内容記述タイプ Abstract
内容記述 The clinical effect of the GABAergic drug gabapentin was evaluated in 11 patients with spinocerebellar ataxia type 6 (SCA6). The total period of gabapentin treatment was 4 weeks, and outcome measures were determined with the International Cooperative Ataxia Rating Scales (ICARS) and postural sway studies. At week 4, 5 patients showed a decrease of the ICARS values by more than 10% compared with the pretreatment baseline. Eight patients showed a more than 10% decrease of the sway area (SA) and/or sway path length (SPL) values in postural sway Studies. The ICARS values and SA/SPL values were not necessarily consistent in each patient, but 3 patients showed a more than 10% decrease in the ICRAS, SA, and SPL values at week 4 when compared to the pre-treatment baseline. As a whole, the efficacy of gabapentin was not statistically confirmed in the 4-week trial because of the variation in efficacy in each patient, but the data are indicative that some SCA6 patients could benefit from gabapentin treatment.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 0022-510X
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00703265
PubMed
関連識別子
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/19157422
関連名称
関連名称 19157422
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.jns.2008.12.017
関連名称
関連名称 10.1016/j.jns.2008.12.017
権利
権利情報 Copyright© 2008 Elsevier B.V.
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000263692300021
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