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Spinocerebellar ataxia type 6 (SCA6): Clinical pilot trial with gabapentin
http://hdl.handle.net/10091/16902
http://hdl.handle.net/10091/16902e35b8412-9d39-4112-9a68-abbb498a12a3
名前 / ファイル | ライセンス | アクション |
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Spinocerebellar_ataxia_type_6_SCA6.pdf (315.2 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-04-01 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Spinocerebellar ataxia type 6 (SCA6): Clinical pilot trial with gabapentin | |||||
言語 | ||||||
言語 | eng | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.jns.2008.12.017 | |||||
関連名称 | 10.1016/j.jns.2008.12.017 | |||||
キーワード | ||||||
主題 | Spinocerebellar ataxia type 6 (SCA6), Gabapentin, The International Cooperative Ataxia Rating Scales (ICARS), Voltage-dependent calcium channel (VDCC), gamma-aminobutyric acid (GABA), Postural sway study | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Nakamura, Katsuya
× Nakamura, Katsuya× Yoshida, Kunihiro× Miyazaki, Daigo× Morita, Hiroshi× Ikeda, Shu-ichi |
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信州大学研究者総覧へのリンク | ||||||
氏名 | Yoshida, Kunihiro | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.yhfNHFkh.html | |||||
信州大学研究者総覧へのリンク | ||||||
氏名 | Morita, Hiroshi | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.HUyNHhkh.html | |||||
出版者 | ||||||
出版者 | ELSEVIER SCIENCE BV | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | JOURNAL OF THE NEUROLOGICAL SCIENCES. 278(1-2):107-111 (2009) | |||||
書誌情報 |
JOURNAL OF THE NEUROLOGICAL SCIENCES 巻 278, 号 1-2, p. 107-111, 発行日 2009-03-15 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The clinical effect of the GABAergic drug gabapentin was evaluated in 11 patients with spinocerebellar ataxia type 6 (SCA6). The total period of gabapentin treatment was 4 weeks, and outcome measures were determined with the International Cooperative Ataxia Rating Scales (ICARS) and postural sway studies. At week 4, 5 patients showed a decrease of the ICARS values by more than 10% compared with the pretreatment baseline. Eight patients showed a more than 10% decrease of the sway area (SA) and/or sway path length (SPL) values in postural sway Studies. The ICARS values and SA/SPL values were not necessarily consistent in each patient, but 3 patients showed a more than 10% decrease in the ICRAS, SA, and SPL values at week 4 when compared to the pre-treatment baseline. As a whole, the efficacy of gabapentin was not statistically confirmed in the 4-week trial because of the variation in efficacy in each patient, but the data are indicative that some SCA6 patients could benefit from gabapentin treatment. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0022-510X | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00703265 | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | https://pubmed.ncbi.nlm.nih.gov/19157422 | |||||
関連名称 | 19157422 | |||||
権利 | ||||||
権利情報 | Copyright© 2008 Elsevier B.V. | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000263692300021 |