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Comparison of acid-induced inflammatory responses in the rat lung during high frequency oscillatory and conventional mechanical ventilation
http://hdl.handle.net/10091/16792
http://hdl.handle.net/10091/167925ffc03f1-628c-46a0-87c5-e7bb974ba47b
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Comparison_acid-induced_inflammatory_responses_rat_lung.pdf (160.4 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2013-03-06 | |||||
| タイトル | ||||||
| タイトル | Comparison of acid-induced inflammatory responses in the rat lung during high frequency oscillatory and conventional mechanical ventilation | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1007/s00011-010-0204-6 | |||||
| 関連名称 | 10.1007/s00011-010-0204-6 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Mechanical ventilation | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Lung injury | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Surfactant | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | ARDS | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | TNF-alpha | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Ventilation-induced lung injury | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Jian, Ming-Yuan
× Jian, Ming-Yuan× Koizumi, Tomonobu× Yokoyama, Toshiki× Tsushima, Kenji× Kubo, Keishi |
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| 信州大学研究者総覧へのリンク | ||||||
| 表示名 | Koizumi, Tomonobu | |||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.WakmHhkh.html | |||||
| 出版者 | ||||||
| 出版者 | SPRINGER BASEL AG | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | INFLAMMATION RESEARCH. 59(11):931-937 (2010) | |||||
| 書誌情報 |
INFLAMMATION RESEARCH 巻 59, 号 11, p. 931-937, 発行日 2010-11 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The present study was performed to compare the effects of high frequency oscillatory ventilation (HFOV) with conventional mechanical ventilation (CMV) on pulmonary inflammatory responses in a rat acid-induced lung injury model. Anesthetized rats were instilled intratracheally with HCl (0.1 N, 2 mL/kg) and then randomly divided into three mechanical ventilation settings: HFOV (an oscillatory frequency of 15 Hz, mean airway pressure (MAP) of 9 cmH(2)O), CMV at tidal volume of 12 and 6 mL/kg for 5 h. After HCl instillation, HFOV significantly attenuated the increases in neutrophil infiltration and TNF-alpha concentration in bronchoalveolar lavage fluid compared with the CMV groups. During HFOV, there was an inhibition of an increase in TNF-alpha mRNA expression and a decrease in SP-A mRNA expression induced by acid instillation. This animal study demonstrates that HFOV is a suitable form of mechanical ventilation to prevent inflammatory responses in acid-induced lung injury. | |||||
| 資源タイプ（コンテンツの種類） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Article | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 1023-3830 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA11030494 | |||||
| PubMed | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | https://pubmed.ncbi.nlm.nih.gov/20425135 | |||||
| 関連名称 | 20425135 | |||||
| 権利 | ||||||
| 権利情報 | The final publication is available at www.springerlink.com | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| WoS | ||||||
| 表示名 | Web of Science | |||||
| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000282218900005 | |||||
