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Dysfunction in ABCB1A Has Only a Weak Effect on Susceptibility to Dextran Sulfate Sodium-Induced Colitis in SAM Strains
http://hdl.handle.net/10091/13264
http://hdl.handle.net/10091/13264c4a801ab-02f3-4523-8fce-c44adb24894e
名前 / ファイル | ライセンス | アクション |
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Dysfunction_ABCB1A_Has_Only_Weak_Effect.pdf (424.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2011-10-11 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Dysfunction in ABCB1A Has Only a Weak Effect on Susceptibility to Dextran Sulfate Sodium-Induced Colitis in SAM Strains | |||||
言語 | ||||||
言語 | eng | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1538/expanim.58.421 | |||||
関連名称 | 10.1538/expanim.58.421 | |||||
キーワード | ||||||
主題 | ABCB1A, dextran sulfate sodium-induced colitis, Senescence-Accelerated Mouse | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Zhang, Guohong
× Zhang, Guohong× Fu, Xiaoying× Takeda, Toshio× Higuchi, Keiichi× Mori, Masayuki |
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信州大学研究者総覧へのリンク | ||||||
氏名 | Higuchi, Keiichi | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.gCfUPmAh.html | |||||
信州大学研究者総覧へのリンク | ||||||
氏名 | Mori, Masayuki | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.OpSCZafV.html | |||||
出版者 | ||||||
出版者 | Japanese Association for Laboratory Animal Science | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | EXPERIMENTAL ANIMALS. 58(4):421-425 (2009) | |||||
書誌情報 |
EXPERIMENTAL ANIMALS 巻 58, 号 4, p. 421-425, 発行日 2009-07 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Genetic alterations in the gene for ATP-binding cassette, sub-family B (MDR/TAP), member 1A (ABCB1A) determine susceptibility to colitis in mice and humans. We investigated the influence of ABCB1A dysfunction on susceptibility to dextran sulfate sodium (DSS)-induced colitis by using Senescence-Accelerated Mouse (SAM) strains with a loss-of-function mutation in the Abcb1a gene (SAMR1, SAMP1, and SAMP6). Susceptibility to DSS colitis was different among SAM strains but on the whole was not different from other mouse strains with normal ABCB1A function. Thus, genetic factors other than loss of ABCB1A are more crucial in determining susceptibility to DSS colitis in SAM strains. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 1341-1357 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11032321 | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | https://pubmed.ncbi.nlm.nih.gov/19654441 | |||||
関連名称 | 19654441 | |||||
権利 | ||||||
権利情報 | Copyright (c) 2009 Japanese Association for Laboratory Animal Science | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000268442400012 |