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  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

Nanoparticle-mediated intracellular lipid accumulation during C2C12 cell differentiation

http://hdl.handle.net/10091/13166
http://hdl.handle.net/10091/13166
2d6dbe60-3b09-4ac5-baa6-818df4d2475d
名前 / ファイル ライセンス アクション
Nanoparticle-mediated_intracellular_lipid_accumulation.pdf Nanoparticle-mediated_intracellular_lipid_accumulation.pdf (669.8 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2011-05-23
タイトル
タイトル Nanoparticle-mediated intracellular lipid accumulation during C2C12 cell differentiation
言語
言語 eng
DOI
関連識別子 https://doi.org/10.1016/j.bbrc.2011.02.090
関連名称 10.1016/j.bbrc.2011.02.090
キーワード
主題 Myoblast, Adipoblast, Multiwall carbon nanotube, Lipid accumulation
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Tsukahara, Tamotsu

× Tsukahara, Tamotsu

en Tsukahara, Tamotsu

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Haniu, Hisao

× Haniu, Hisao

en Haniu, Hisao

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信州大学研究者総覧へのリンク
氏名 Haniu, Hisao
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.jakpPmSa.html
出版者
出版者 ACADEMIC PRESS INC ELSEVIER SCIENCE
引用
内容記述 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 406(4):558-563 (2011)
書誌情報 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

巻 406, 号 4, p. 558-563, 発行日 2011-03-25
抄録
内容記述 In this report, we sought to elucidate whether multiwall carbon nanotubes are involved in the modulation of the proliferation and differentiation of the skeletal muscle cell line C2C12. Skeletal muscle is a major mass peripheral tissue that accounts for 40% of total body weight and 50% of energy consumption. We focused on the differentiation pathway of myoblasts after exposure to a vapor-grown carbon fiber, HTT2800, which is one of the most highly purified carbon nanotubes. This treatment leads in parallel to the expression of a typical adipose differentiation program. We found that HTT2800 stimulated intracellular lipid accumulation in C2C12 cells. We have also shown by quantified PCR analysis that the expression of adipose-related genes was markedly upregulated during HTT2800 exposure. Taken together, these results suggest that HTT2800 specifically converts the differentiation pathway of C2C12 myoblasts to that of adipoblast-like cells.
資源タイプ(コンテンツの種類)
ISSN
収録物識別子タイプ PISSN
収録物識別子 0006-291X
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00564395
PubMed
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/21354108
関連名称 21354108
権利
権利情報 Copyright (c) 2011 Elsevier Inc
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000289036600012
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Cite as

Tsukahara, Tamotsu, Haniu, Hisao, 2011, Nanoparticle-mediated intracellular lipid accumulation during C2C12 cell differentiation: ACADEMIC PRESS INC ELSEVIER SCIENCE, 558–563 p.

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