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Nanoparticle-mediated intracellular lipid accumulation during C2C12 cell differentiation
http://hdl.handle.net/10091/13166
http://hdl.handle.net/10091/131662d6dbe60-3b09-4ac5-baa6-818df4d2475d
| 名前 / ファイル | ライセンス | アクション |
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Nanoparticle-mediated_intracellular_lipid_accumulation.pdf (669.8 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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| 公開日 | 2011-05-23 | |||||||||
| タイトル | ||||||||||
| タイトル | Nanoparticle-mediated intracellular lipid accumulation during C2C12 cell differentiation | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| DOI | ||||||||||
| 関連識別子 | https://doi.org/10.1016/j.bbrc.2011.02.090 | |||||||||
| 関連名称 | 10.1016/j.bbrc.2011.02.090 | |||||||||
| キーワード | ||||||||||
| 主題 | Myoblast, Adipoblast, Multiwall carbon nanotube, Lipid accumulation | |||||||||
| 資源タイプ | ||||||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| タイプ | journal article | |||||||||
| 著者 |
Tsukahara, Tamotsu
× Tsukahara, Tamotsu
× Haniu, Hisao
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| 信州大学研究者総覧へのリンク | ||||||||||
| 氏名 | Haniu, Hisao | |||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.jakpPmSa.html | |||||||||
| 出版者 | ||||||||||
| 出版者 | ACADEMIC PRESS INC ELSEVIER SCIENCE | |||||||||
| 引用 | ||||||||||
| 内容記述 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 406(4):558-563 (2011) | |||||||||
| 書誌情報 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 巻 406, 号 4, p. 558-563, 発行日 2011-03-25 |
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| 抄録 | ||||||||||
| 内容記述 | In this report, we sought to elucidate whether multiwall carbon nanotubes are involved in the modulation of the proliferation and differentiation of the skeletal muscle cell line C2C12. Skeletal muscle is a major mass peripheral tissue that accounts for 40% of total body weight and 50% of energy consumption. We focused on the differentiation pathway of myoblasts after exposure to a vapor-grown carbon fiber, HTT2800, which is one of the most highly purified carbon nanotubes. This treatment leads in parallel to the expression of a typical adipose differentiation program. We found that HTT2800 stimulated intracellular lipid accumulation in C2C12 cells. We have also shown by quantified PCR analysis that the expression of adipose-related genes was markedly upregulated during HTT2800 exposure. Taken together, these results suggest that HTT2800 specifically converts the differentiation pathway of C2C12 myoblasts to that of adipoblast-like cells. | |||||||||
| 資源タイプ（コンテンツの種類） | ||||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | PISSN | |||||||||
| 収録物識別子 | 0006-291X | |||||||||
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| 収録物識別子タイプ | NCID | |||||||||
| 収録物識別子 | AA00564395 | |||||||||
| PubMed | ||||||||||
| 識別子タイプ | PMID | |||||||||
| 関連識別子 | https://pubmed.ncbi.nlm.nih.gov/21354108 | |||||||||
| 関連名称 | 21354108 | |||||||||
| 権利 | ||||||||||
| 権利情報 | Copyright (c) 2011 Elsevier Inc | |||||||||
| 出版タイプ | ||||||||||
| 出版タイプ | AM | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||
| WoS | ||||||||||
| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000289036600012 | |||||||||
