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Several reports of G-CSF-producing malignant tumors have been published, but scarcely any in the hepatobiliary system, such as in hepatocellular carcinoma (HCC). Here, we encountered a 69-yr-old man with a hepatic tumor who had received right hepatic resection. He showed leukocytosis of 25,450/mL along with elevated serum G-CSF. Histological examination of surgical samples demonstrated immunohistochemical staining for G-CSF, but not for G-CSF receptor. The patient survived without recurrence for four years, but ultimately passed away with multiple bone metastases. In light of the above, clinicians may consider G-CSF-producing HCC when encountering patients with leukocytosis and a hepatic tumor. 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Several reports of G-CSF-producing malignant tumors have been published, but scarcely any in the hepatobiliary system, such as in hepatocellular carcinoma (HCC). Here, we encountered a 69-yr-old man with a hepatic tumor who had received right hepatic resection. He showed leukocytosis of 25,450/mL along with elevated serum G-CSF. Histological examination of surgical samples demonstrated immunohistochemical staining for G-CSF, but not for G-CSF receptor. The patient survived without recurrence for four years, but ultimately passed away with multiple bone metastases. In light of the above, clinicians may consider G-CSF-producing HCC when encountering patients with leukocytosis and a hepatic tumor. More cases are needed to clarify the clinical picture of G-CSF-producing HCC."}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Joshita,  Satoru"}], "nameIdentifiers": [{"nameIdentifier": "7645", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakazawa,  Koh"}], "nameIdentifiers": [{"nameIdentifier": "7646", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Koike,  Shoichiro"}], "nameIdentifiers": [{"nameIdentifier": "7647", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kamijo,  Atsushi"}], "nameIdentifiers": [{"nameIdentifier": "7648", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsubayashi,  Kiyoshi"}], "nameIdentifiers": [{"nameIdentifier": "7649", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Miyabayashi,  Hideharu"}], "nameIdentifiers": [{"nameIdentifier": "7650", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Furuta,  Kiyoshi"}], "nameIdentifiers": [{"nameIdentifier": "7651", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kitano,  Kiyoshi"}], "nameIdentifiers": [{"nameIdentifier": "7652", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshizawa,  Kaname"}], "nameIdentifiers": [{"nameIdentifier": "7653", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka,  Eiji"}], "nameIdentifiers": [{"nameIdentifier": "7654", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Granulocyte-Colony_Stimulating_Factor-Producing.pdf", "filesize": [{"value": "330.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 330800.0, "url": {"label": "Granulocyte-Colony_Stimulating_Factor-Producing.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/3867/files/Granulocyte-Colony_Stimulating_Factor-Producing.pdf"}, "version_id": "0fd14de0-9ba8-42c7-a75a-fcd1ce45c699"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "G-CSF-producing Tumor", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Carcinoma, Hepatocellular, Immunohistochemistry", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "A Case of Granulocyte-Colony Stimulating Factor-Producing Hepatocellular Carcinoma Confirmed by Immunohistochemistry", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "A Case of Granulocyte-Colony Stimulating Factor-Producing Hepatocellular Carcinoma Confirmed by Immunohistochemistry"}]}, "item_type_id": "6", "owner": "1", "path": ["461/462"], "permalink_uri": "http://hdl.handle.net/10091/11100", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2011-01-18"}, "publish_date": "2011-01-18", "publish_status": "0", "recid": "3867", "relation": {}, "relation_version_is_last": true, "title": ["A Case of Granulocyte-Colony Stimulating Factor-Producing Hepatocellular Carcinoma Confirmed by Immunohistochemistry"], "weko_shared_id": 3}