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Increased isoprostane levels in oleic acid-induced lung injury
http://hdl.handle.net/10091/11096
http://hdl.handle.net/10091/1109604e50f48-6165-4763-9550-4ef94a7b357d
| 名前 / ファイル | ライセンス | アクション |
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Increased_isoprostane_levels_oleic_acid.pdf (263.6 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2011-01-17 | |||||
| タイトル | ||||||
| タイトル | Increased isoprostane levels in oleic acid-induced lung injury | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| DOI | ||||||
| 関連識別子 | https://doi.org/10.1016/j.bbrc.2009.07.157 | |||||
| 関連名称 | 10.1016/j.bbrc.2009.07.157 | |||||
| キーワード | ||||||
| 主題 | Oleic acid-induced lung injury, Lung lymph flow, Increased permeability edema, Sheep, Oxidant stress | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Ono, Koichi
× Ono, Koichi× Koizumi, Tomonobu× Tsushima, Kenji× Yoshikawa, Sumiko× Yokoyama, Toshiki× Nakagawa, Rikimaru× Obata, Toru |
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| 信州大学研究者総覧へのリンク | ||||||
| 表示名 | Koizumi, Tomonobu | |||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.WakmHhkh.html | |||||
| 出版者 | ||||||
| 出版者 | ACADEMIC PRESS INC ELSEVIER SCIENCE | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 388(2):297-300 (2009) | |||||
| 書誌情報 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 巻 388, 号 2, p. 297-300, 発行日 2009-10-16 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The present study was performed to examine a role of oxidative stress in oleic acid-induced lung injury model. Fifteen anesthetized sheep were ventilated and instrumented with a lung lymph fistula and vascular catheters for blood gas analysis and measurement of isoprostanes (8-epi prostaglandin F2 alpha). Following stable baseline measurements, oleic acid (0.08 ml/kg) was administered and observed 4 h. Isoprostane was measured by gas chromatography mass spectrometry with the isotope dilution method. Isoprostane levels in plasma and lung lymph were significantly increased 2 h after oleic acid administration and then decreased at 4 h. The percent increases in isoprostane levels in plasma and lung lymph at 2 h were significantly correlated with deteriorated oxygenation at the same time point, respectively. These findings suggest that oxidative stress is involved in the pathogenesis of the pulmonary fat embolism-induced acute lung injury model in sheep and that the increase relates with the deteriorated oxygenation. | |||||
| 資源タイプ（コンテンツの種類） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Article | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0006-291X | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00564395 | |||||
| PubMed | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | https://pubmed.ncbi.nlm.nih.gov/19664592 | |||||
| 関連名称 | 19664592 | |||||
| 権利 | ||||||
| 権利情報 | Copyright (c) 2009 Elsevier Inc. | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| WoS | ||||||
| 表示名 | Web of Science | |||||
| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000274534300022 | |||||
