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To verify occurrence of PPAR\u03b1-independent peroxisome proliferation, fenofibrate treatment was used, which was expected to significantly enhance PPAR\u03b1 dependence in the assay system. Surprisingly, a novel type of PPAR\u03b1-independent peroxisome proliferation and enlargement was uncovered in PPAR\u03b1-null mice. 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To verify occurrence of PPAR alpha-independent peroxisome proliferation, fenofibrate treatment was used. which was expected to significantly enhance PPAR alpha dependence in the assay system. Surprisingly, a novel type of PPAR alpha-independent peroxisome proliferation and enlargement was uncovered in PPAR alpha-null mice. The increased expression of dynamin-like protein 1, but not peroxisome biogenesis factor 11 alpha, might be associated with the PPAR alpha-independent peroxisome proliferation at least in part. (c) 2006 Elsevier Inc. All rights reserved."}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Zhang,  XG", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8134", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka,  N", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8135", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakajima,  T", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8136", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kamijo,  Y", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8137", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Gonzalez,  FJ", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8138", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Aoyama,  T", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8139", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "PPARa-independentPP_ZhangX_etal.pdf", "filesize": [{"value": "184.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 184900.0, "url": {"label": "PPARa-independentPP_ZhangX_etal.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/3937/files/PPARa-independentPP_ZhangX_etal.pdf"}, "version_id": "0eacf014-4891-470c-8122-7f1ac6d398d2"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "peroxisome proliferator-activated receptor \u03b1", "subitem_subject_scheme": "Other"}, {"subitem_subject": "peroxisome proliferation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "morphometry", "subitem_subject_scheme": "Other"}, {"subitem_subject": "dynamin-like protein 1", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Peroxisome proliferator-activated receptor \u03b1-independent peroxisome proliferation", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Peroxisome proliferator-activated receptor \u03b1-independent peroxisome proliferation", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["461/462"], "permalink_uri": "http://hdl.handle.net/10091/3105", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2009-06-18"}, "publish_date": "2009-06-18", "publish_status": "0", "recid": "3937", "relation": {}, "relation_version_is_last": true, "title": ["Peroxisome proliferator-activated receptor \u03b1-independent peroxisome proliferation"], "weko_shared_id": -1}