{"_buckets": {"deposit": "531ee54f-03b5-4963-ad87-c202fc9f4a81"}, "_deposit": {"id": "4181", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "4181"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00004181"}, "item_6_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2010-06-10", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "114", "bibliographicPageStart": "103", "bibliographicVolumeNumber": "58", "bibliographic_titles": [{"bibliographic_title": "\u4fe1\u5dde\u533b\u5b66\u96d1\u8a8c"}]}]}, "item_6_description_20": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Background :To clarify the mechanisms of lower urinary tract symptoms (LUTS) associated with benign prostate hyperplasia (BPH), we investigated the expression of \u03b11-adrenergic receptor (AR) subtypes and the angiotensin II type 1 receptor (AT1) within the prostate of spontaneously hypertensive rats (SHRs). Methods :Twelve male 25-week-old SHRs and Wistar Kyoto (WKY) rats were randomly separated into two groups (n =6 each). One group was given 20 ml 0.9% sodium chloride solution (saline) orally per kg-body weight daily for one week. The other group received no treatment. After 7 days of saline loading, systolic blood pressure (SBP) and prostate weight were measured. The prostates were immunohistochemically analyzed for \u03b11-AR subtypes and AT1. Results :After 7 days, the SBP and prostate weight of saline-loaded SHRs tended to increase, but was not significantly different compared to the untreated rats.The expression of\u03b11-AR subtypes and AT1 within the prostates of saline-loaded SHRs was higher than in the untreated ones. In contrast, the expression in the saline-loaded WKY rat prostates did not increase compared to the untreated ones. Conclusion : Increased numbers of \u03b11-AR subtypes and AT1 in saline-loaded SHR prostates might play important roles in the development of LUTS associated with BPH.", "subitem_description_type": "Abstract"}]}, "item_6_description_30": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7\uff08\u30b3\u30f3\u30c6\u30f3\u30c4\u306e\u7a2e\u985e\uff09", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_31": {"attribute_name": "\u30d5\u30a9\u30fc\u30de\u30c3\u30c8\uff1amime\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "\u5f15\u7528", "attribute_value_mlt": [{"subitem_description": "\u4fe1\u5dde\u533b\u5b66\u96d1\u8a8c. 58(3): 103-114 (2010)", "subitem_description_type": "Other"}]}, "item_6_link_3": {"attribute_name": "\u4fe1\u5dde\u5927\u5b66\u7814\u7a76\u8005\u7dcf\u89a7\u3078\u306e\u30ea\u30f3\u30af", "attribute_value_mlt": [{"subitem_link_text": "ISHIZUKA, Osamu", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.gmfaHekh.html"}, {"subitem_link_text": "NISHIZAWA, Osamu", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.WeyeWmyU.html"}]}, "item_6_publisher_4": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u4fe1\u5dde\u533b\u5b66\u4f1a"}]}, "item_6_select_64": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_6_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0037-3826", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0037-3826", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_40": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00120815", "subitem_source_identifier_type": "NCID"}]}, "item_6_text_66": {"attribute_name": "sortkey", "attribute_value_mlt": [{"subitem_text_value": "03"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "NAKAYAMA,  Tsuyoshi"}], "nameIdentifiers": [{"nameIdentifier": "9510", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "IMAMURA,  Tetsuya"}], "nameIdentifiers": [{"nameIdentifier": "9511", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "ISHIZUKA,  Osamu"}], "nameIdentifiers": [{"nameIdentifier": "9512", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "NISHIZAWA,  Osamu"}], "nameIdentifiers": [{"nameIdentifier": "9513", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Shinshu_Med58-3-03.pdf", "filesize": [{"value": "2.2 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2200000.0, "url": {"label": "Shinshu_Med58-3-03.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/4181/files/Shinshu_Med58-3-03.pdf"}, "version_id": "deb0745f-d4dc-447c-b906-3764904894b6"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "irradiation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "human lung fibroblast", "subitem_subject_scheme": "Other"}, {"subitem_subject": "chemotaxis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "IL-8", "subitem_subject_scheme": "Other"}, {"subitem_subject": "MCP-1", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Expression of \u03b11-Adrenergic Receptor Subtypes and Angiotensin II Type 1 Receptor in the Prostate of Spontaneously Hypertensive Rats", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Expression of \u03b11-Adrenergic Receptor Subtypes and Angiotensin II Type 1 Receptor in the Prostate of Spontaneously Hypertensive Rats"}]}, "item_type_id": "6", "owner": "1", "path": ["461/463/464/496"], "permalink_uri": "http://hdl.handle.net/10091/10139", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2010-06-23"}, "publish_date": "2010-06-23", "publish_status": "0", "recid": "4181", "relation": {}, "relation_version_is_last": true, "title": ["Expression of \u03b11-Adrenergic Receptor Subtypes and Angiotensin II Type 1 Receptor in the Prostate of Spontaneously Hypertensive Rats"], "weko_shared_id": null}