{"_buckets": {"deposit": "2dc64771-8a86-4ce6-b5cc-c95953464de6"}, "_deposit": {"id": "6933", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6933"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00006933"}, "item_10_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\uff08\u5225\u8a00\u8a9e\u7b49\uff09\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "A Novel Lectin-Affinity Assay of Thyroglobulin in Thyroid Aspirated Specimens : A Clue to the Diagnosis of Differentiated Thyroid Cancer"}]}, "item_10_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1994-02-28", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "28", "bibliographicPageStart": "23", "bibliographicVolumeNumber": "19", "bibliographic_titles": [{"bibliographic_title": "\u7d00\u8981"}]}]}, "item_10_description_20": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "The sugar chain residue of thyroglobulin produced in thyroid cancer (C-Tg) has a modified structure compared with that in the normal thyroid (N-Tg). We have measured the remaining unbound-thyroglobulin (ub-Tg) in thyroid specimens by an enzyme immunoassay (EIA) after treatment with concanavalin A (ConA) lectin, taking advantage of different affinity of C-Tg to lectin. Three thyroid tissue specimens ( 1 normal, 1 papillary  carcinoma, 1 benign goitor) and 28 thyroid aspirated specimens (16 papillary carcinoma and 12 benign goiter) were analyzed. Tg to lectin ratio of 1 : 3 was at the zenith of the ub-Tg\uff05. Thus, ConA at a ratio of 1 : 3 were used for subsequent studies. The ub-Tg value for papillary carcinoma tissue was significantly higher than the benign goiter. Five of 16 specimens obtained by aspiration from thyroid cancer manifested elevated ub-Tg levels after ConA treatment. 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