WEKO3
アイテム
甲状腺穿刺液サイログロブリンのレクチン親和測定法 : 甲状腺分化癌診断の可能性
http://hdl.handle.net/10091/5175
http://hdl.handle.net/10091/51758cfbc993-e162-45fa-b4e3-17b432a7acf6
名前 / ファイル | ライセンス | アクション |
---|---|---|
Allied_Med19_04.pdf (649.5 kB)
|
|
Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
公開日 | 2010-03-01 | |||||||||||
タイトル | ||||||||||||
タイトル | 甲状腺穿刺液サイログロブリンのレクチン親和測定法 : 甲状腺分化癌診断の可能性 | |||||||||||
タイトル | ||||||||||||
タイトル | A Novel Lectin-Affinity Assay of Thyroglobulin in Thyroid Aspirated Specimens : A Clue to the Diagnosis of Differentiated Thyroid Cancer | |||||||||||
言語 | ||||||||||||
言語 | jpn | |||||||||||
キーワード | ||||||||||||
主題 | Lectin, ConcanvalinA, Thyroglobulin, Aspirated Specimens, Thyroid Cancer レクチン, コンカナバリンA, サイログロブリン, 穿刺液, 甲状腺癌 |
|||||||||||
資源タイプ | ||||||||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
タイプ | departmental bulletin paper | |||||||||||
著者 |
加藤, 亮二
× 加藤, 亮二
× 菅谷, 昭
× 飯田, 太
|
|||||||||||
出版者 | ||||||||||||
出版者 | 信州大学医療技術短期大学部 | |||||||||||
引用 | ||||||||||||
内容記述 | 紀要 19: 23-28(1994) | |||||||||||
書誌情報 |
紀要 巻 19, p. 23-28, 発行日 1994-02-28 |
|||||||||||
抄録 | ||||||||||||
内容記述 | The sugar chain residue of thyroglobulin produced in thyroid cancer (C-Tg) has a modified structure compared with that in the normal thyroid (N-Tg). We have measured the remaining unbound-thyroglobulin (ub-Tg) in thyroid specimens by an enzyme immunoassay (EIA) after treatment with concanavalin A (ConA) lectin, taking advantage of different affinity of C-Tg to lectin. Three thyroid tissue specimens ( 1 normal, 1 papillary carcinoma, 1 benign goitor) and 28 thyroid aspirated specimens (16 papillary carcinoma and 12 benign goiter) were analyzed. Tg to lectin ratio of 1 : 3 was at the zenith of the ub-Tg%. Thus, ConA at a ratio of 1 : 3 were used for subsequent studies. The ub-Tg value for papillary carcinoma tissue was significantly higher than the benign goiter. Five of 16 specimens obtained by aspiration from thyroid cancer manifested elevated ub-Tg levels after ConA treatment. Thus, measurement of ub-Tg in thyroid aspirated specimens after treatment with ConA may prove to be useful for the diagnosis of thyroid cancer. | |||||||||||
資源タイプ(コンテンツの種類) | ||||||||||||
内容記述 | Article | |||||||||||
ISSN | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 0385-1982 | |||||||||||
書誌レコードID | ||||||||||||
収録物識別子タイプ | NCID | |||||||||||
収録物識別子 | AN10402438 |