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  1. 055 医学部附属病院
  2. 0551 学術論文

The effect of a prostaglandin E-1 derivative on the symptoms and quality of life of patients with lumbar spinal stenosis

http://hdl.handle.net/10091/17834
4484594e-3ebb-4a46-bbcb-ebd1cf275de9
名前 / ファイル ライセンス アクション
prostaglandin_E-1_derivative_symptoms_qol.pdf prostaglandin_E-1_derivative_symptoms_qol.pdf (233.7 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-09-05
タイトル
言語 en
タイトル The effect of a prostaglandin E-1 derivative on the symptoms and quality of life of patients with lumbar spinal stenosis
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Takahashi, Jun

× Takahashi, Jun

WEKO 21915

en Takahashi, Jun

Search repository
Kobayashi, Hirokazu

× Kobayashi, Hirokazu

WEKO 21916

en Kobayashi, Hirokazu

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Wakabayashi, Shinji

× Wakabayashi, Shinji

WEKO 21917

en Wakabayashi, Shinji

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Deguchi, Masao

× Deguchi, Masao

WEKO 21918

en Deguchi, Masao

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Ito, Hidehiro

× Ito, Hidehiro

WEKO 21919

en Ito, Hidehiro

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Mogami, Yuji

× Mogami, Yuji

WEKO 21920

en Mogami, Yuji

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Tanikawa, Hirotaka

× Tanikawa, Hirotaka

WEKO 21921

en Tanikawa, Hirotaka

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Nakagawa, Hiroyuki

× Nakagawa, Hiroyuki

WEKO 21922

en Nakagawa, Hiroyuki

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Moriya, Hideki

× Moriya, Hideki

WEKO 21923

en Moriya, Hideki

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Ashizawa, Ryohei

× Ashizawa, Ryohei

WEKO 21924

en Ashizawa, Ryohei

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Takahara, Kenji

× Takahara, Kenji

WEKO 21925

en Takahara, Kenji

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Kinoshita, Hisatoshi

× Kinoshita, Hisatoshi

WEKO 21926

en Kinoshita, Hisatoshi

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Tateiwa, Yutaka

× Tateiwa, Yutaka

WEKO 21927

en Tateiwa, Yutaka

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Misawa, Hiromichi

× Misawa, Hiromichi

WEKO 21928

en Misawa, Hiromichi

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Tsutsumimoto, Takahiro

× Tsutsumimoto, Takahiro

WEKO 21929

en Tsutsumimoto, Takahiro

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Nakakohji, Taku

× Nakakohji, Taku

WEKO 21930

en Nakakohji, Taku

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Yuzawa, Yohei

× Yuzawa, Yohei

WEKO 21931

en Yuzawa, Yohei

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Sawaumi, Akihito

× Sawaumi, Akihito

WEKO 21932

en Sawaumi, Akihito

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Hidai, Yohei

× Hidai, Yohei

WEKO 21933

en Hidai, Yohei

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Matsuda, Satoshi

× Matsuda, Satoshi

WEKO 21934

en Matsuda, Satoshi

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Nakamura, Isao

× Nakamura, Isao

WEKO 21935

en Nakamura, Isao

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Toba, Shigeyuki

× Toba, Shigeyuki

WEKO 21936

en Toba, Shigeyuki

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Kamimura, Mikio

× Kamimura, Mikio

WEKO 21937

en Kamimura, Mikio

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Nakane, Takeshi

× Nakane, Takeshi

WEKO 21938

en Nakane, Takeshi

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Hirabayashi, Hiroki

× Hirabayashi, Hiroki

WEKO 21939

en Hirabayashi, Hiroki

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Hashidate, Hiroyuki

× Hashidate, Hiroyuki

WEKO 21940

en Hashidate, Hiroyuki

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Ogihara, Nobuhide

× Ogihara, Nobuhide

WEKO 21941

en Ogihara, Nobuhide

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Mukaiyama, Keijiro

× Mukaiyama, Keijiro

WEKO 21942

en Mukaiyama, Keijiro

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Kato, Hiroyuki

× Kato, Hiroyuki

WEKO 21943

en Kato, Hiroyuki

Search repository
Ohtsuka, Kuniyoshi

× Ohtsuka, Kuniyoshi

WEKO 21944

en Ohtsuka, Kuniyoshi

Search repository
信州大学研究者総覧へのリンク
氏名 Takahashi, Jun
URL https://soar-rd.shinshu-u.ac.jp/profile/ja.jeAhuakh.html
信州大学研究者総覧へのリンク
氏名 Kato, Hiroyuki
URL https://soar-rd.shinshu-u.ac.jp/profile/ja.WVkCbaSp.html
出版者
出版者 SPRINGER JAPAN KK
引用
内容記述タイプ Other
内容記述 JOURNAL OF ORTHOPAEDIC SCIENCE. 18(2):208-215 (2013)
書誌情報 JOURNAL OF ORTHOPAEDIC SCIENCE

巻 18, 号 2, p. 208-215, 発行日 2013-03
抄録
内容記述タイプ Abstract
内容記述 Quality of life (QOL) is a concern for patients with lumbar spinal stenosis (LSS). In this study, QOL was examined using the 5-item EuroQol (EQ-5D). QOL and activities of daily living (ADL) were surveyed for 91 patients who visited 18 medical institutions in our prefecture and were diagnosed with LSS-associated intermittent claudication. A second survey was performed after a parts per thousand yen6 weeks for 79 of the subjects to evaluate therapy with limaprost (an oral prostaglandin E1 derivative) or etodolac (an NSAID). Symptoms, maximum walking time, QOL, ADL items, and relationships among these variables were investigated for all 91 patients. Leg pain, leg numbness, and low back pain while walking were surveyed by use of VAS scores (0-100). Leg pain, leg numbness, and low back pain while walking (VAS a parts per thousand yen25) were present in 83.5, 62.6, and 54.9 % of the patients in the first survey, and approximately half of the patients had a maximum walking time < 15 min. The mean EQ-5D utility value for QOL was 0.59 +/- A 0.12. This value was significantly associated with maximum walking time (p = 0.030) based on classification of patients into groups with walking times < 7.5, 7.5-15, 15-30, and > 30 min, showing that maximum walking time affected health-related QOL. Of the 79 patients who completed the second survey, 56 had taken limaprost and 23 (control group) had received etodolac. Limaprost improved possible walking time, reduced ADL interference, and significantly increased the EQ-5D utility score, whereas no significant changes occurred in the control group. Maximum walking time was prolonged by a parts per thousand yen10 min and the EQ-5D utility value was improved by a parts per thousand yen0.1 points in significantly more patients in the limaprost group than in the control group. According to the findings of this survey, at an average of 8 weeks after administration limaprost improved symptoms, QOL, and ADL in LSS patients whereas treatment with an NSAID reduced pain but did not have any other effects.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 0949-2658
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA11052566
PubMed
関連識別子
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/23203845
関連名称
関連名称 23203845
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1007/s00776-012-0342-5
関連名称
関連名称 10.1007/s00776-012-0342-5
権利
権利情報 Copyright© 2012 The Japanese Orthopaedic Association
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000316752600004
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