Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2014-09-05 |
タイトル |
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タイトル |
The effect of a prostaglandin E-1 derivative on the symptoms and quality of life of patients with lumbar spinal stenosis |
言語 |
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言語 |
eng |
DOI |
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関連識別子 |
https://doi.org/10.1007/s00776-012-0342-5 |
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関連名称 |
10.1007/s00776-012-0342-5 |
資源タイプ |
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資源 |
http://purl.org/coar/resource_type/c_6501 |
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タイプ |
journal article |
著者 |
Takahashi, Jun
Kobayashi, Hirokazu
Wakabayashi, Shinji
Deguchi, Masao
Ito, Hidehiro
Mogami, Yuji
Tanikawa, Hirotaka
Nakagawa, Hiroyuki
Moriya, Hideki
Ashizawa, Ryohei
Takahara, Kenji
Kinoshita, Hisatoshi
Tateiwa, Yutaka
Misawa, Hiromichi
Tsutsumimoto, Takahiro
Nakakohji, Taku
Yuzawa, Yohei
Sawaumi, Akihito
Hidai, Yohei
Matsuda, Satoshi
Nakamura, Isao
Toba, Shigeyuki
Kamimura, Mikio
Nakane, Takeshi
Hirabayashi, Hiroki
Hashidate, Hiroyuki
Ogihara, Nobuhide
Mukaiyama, Keijiro
Kato, Hiroyuki
Ohtsuka, Kuniyoshi
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信州大学研究者総覧へのリンク |
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氏名 |
Takahashi, Jun |
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URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.jeAhuakh.html |
信州大学研究者総覧へのリンク |
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氏名 |
Kato, Hiroyuki |
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URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.WVkCbaSp.html |
出版者 |
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出版者 |
SPRINGER JAPAN KK |
引用 |
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内容記述 |
JOURNAL OF ORTHOPAEDIC SCIENCE. 18(2):208-215 (2013) |
書誌情報 |
JOURNAL OF ORTHOPAEDIC SCIENCE
巻 18,
号 2,
p. 208-215,
発行日 2013-03
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抄録 |
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内容記述 |
Quality of life (QOL) is a concern for patients with lumbar spinal stenosis (LSS). In this study, QOL was examined using the 5-item EuroQol (EQ-5D). QOL and activities of daily living (ADL) were surveyed for 91 patients who visited 18 medical institutions in our prefecture and were diagnosed with LSS-associated intermittent claudication. A second survey was performed after a parts per thousand yen6 weeks for 79 of the subjects to evaluate therapy with limaprost (an oral prostaglandin E1 derivative) or etodolac (an NSAID). Symptoms, maximum walking time, QOL, ADL items, and relationships among these variables were investigated for all 91 patients. Leg pain, leg numbness, and low back pain while walking were surveyed by use of VAS scores (0-100). Leg pain, leg numbness, and low back pain while walking (VAS a parts per thousand yen25) were present in 83.5, 62.6, and 54.9 % of the patients in the first survey, and approximately half of the patients had a maximum walking time < 15 min. The mean EQ-5D utility value for QOL was 0.59 +/- A 0.12. This value was significantly associated with maximum walking time (p = 0.030) based on classification of patients into groups with walking times < 7.5, 7.5-15, 15-30, and > 30 min, showing that maximum walking time affected health-related QOL. Of the 79 patients who completed the second survey, 56 had taken limaprost and 23 (control group) had received etodolac. Limaprost improved possible walking time, reduced ADL interference, and significantly increased the EQ-5D utility score, whereas no significant changes occurred in the control group. Maximum walking time was prolonged by a parts per thousand yen10 min and the EQ-5D utility value was improved by a parts per thousand yen0.1 points in significantly more patients in the limaprost group than in the control group. According to the findings of this survey, at an average of 8 weeks after administration limaprost improved symptoms, QOL, and ADL in LSS patients whereas treatment with an NSAID reduced pain but did not have any other effects. |
資源タイプ(コンテンツの種類) |
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内容記述 |
Article |
ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0949-2658 |
書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA11052566 |
PubMed |
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関連識別子 |
https://pubmed.ncbi.nlm.nih.gov/23203845 |
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関連名称 |
23203845 |
権利 |
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権利情報 |
Copyright© 2012 The Japanese Orthopaedic Association |
出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
WoS |
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URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000316752600004 |