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  1. 055 医学部附属病院
  2. 0551 学術論文

Antigen p57/Kip2 as a potential negative regulator of human astrocytoma growth

http://hdl.handle.net/10091/16946
4ebcd076-fb22-444e-8f3b-26e2a9b219fe
名前 / ファイル ライセンス アクション
Antigen_p57_Kip2_potential_negative_regulator_human.pdf Antigen_p57_Kip2_potential_negative_regulator_human.pdf (282.8 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2013-04-23
タイトル
言語 en
タイトル Antigen p57/Kip2 as a potential negative regulator of human astrocytoma growth
言語
言語 eng
キーワード
主題Scheme Other
主題 Astrocytoma
キーワード
主題Scheme Other
主題 Cell proliferation
キーワード
主題Scheme Other
主題 p16
キーワード
主題Scheme Other
主題 p57/Kip2
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Akaishi, Kotaro

× Akaishi, Kotaro

WEKO 22307

en Akaishi, Kotaro

Search repository
Nakayama, Jun

× Nakayama, Jun

WEKO 22308

en Nakayama, Jun

Search repository
Sakai, Keiichi

× Sakai, Keiichi

WEKO 22309

en Sakai, Keiichi

Search repository
Kobayashi, Tatsuya

× Kobayashi, Tatsuya

WEKO 22310

en Kobayashi, Tatsuya

Search repository
Rutka, James T

× Rutka, James T

WEKO 22311

en Rutka, James T

Search repository
信州大学研究者総覧へのリンク
氏名 Nakayama, Jun
URL https://soar-rd.shinshu-u.ac.jp/profile/ja.HCApHFkh.html
出版者
出版者 ELSEVIER SCI LTD
引用
内容記述タイプ Other
内容記述 JOURNAL OF CLINICAL NEUROSCIENCE. 16(12):1615-1618 (2009)
書誌情報 JOURNAL OF CLINICAL NEUROSCIENCE

巻 16, 号 12, p. 1615-1618, 発行日 2009-12
抄録
内容記述タイプ Abstract
内容記述 This study was performed to determine the relationship between p57/Kip2 and the growth of human astrocytomas. Immunohistochemical staining for p57/Kip2, p53, p16, and Ki67 antigen was performed on paraffin-embedded tissue specimens obtained from 36 patients with astrocytoma. Expression of p57/Kip2, p53, p16, and Ki67 antigen was generally increased in association with the astrocytoma tumor grade. Expression of p16 was higher in patients whose tumors express p57/Kip2 in greater than 10% of tumor cells (p < 0.05). Expression of p53 also tended to be higher, but not to a statistically significant extent, in patients whose tumors express p57/Kip2 in greater than 10% of tumor cells. These findings suggest that p57/Kip2 inhibits the growth of human astrocytomas, and may function in parallel with p16 and p53. However, p57/Kip2 is, by itself, insufficient to arrest the cellular proliferation of human astrocytomas.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ EISSN
収録物識別子 0967-5868
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA10958444
PubMed
関連識別子
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/19822429
関連名称
関連名称 19822429
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.jocn.2009.05.007
関連名称
関連名称 10.1016/j.jocn.2009.05.007
権利
権利情報 Copyright© 2009 Elsevier Ltd.
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000271917800017
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