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  1. 055 医学部附属病院 (Hospital)
  2. 0551 学術論文 (Journal Articles)

Antigen p57/Kip2 as a potential negative regulator of human astrocytoma growth

http://hdl.handle.net/10091/16946
4ebcd076-fb22-444e-8f3b-26e2a9b219fe
プレビュー
名前 / ファイル ライセンス Actions
Antigen_p57_Kip2_potential_negative_regulator_human.pdf Antigen_p57_Kip2_potential_negative_regulator_human.pdf (282.8 kB)
item type 学術雑誌論文 / Journal Article(1)
公開日 2013-04-23
タイトル
タイトル Antigen p57/Kip2 as a potential negative regulator of human astrocytoma growth
言語
言語 eng
キーワード
主題 Astrocytoma
キーワード
主題 Cell proliferation
キーワード
主題 p16
キーワード
主題 p57/Kip2
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Akaishi, Kotaro

× Akaishi, Kotaro

WEKO 22307

Akaishi, Kotaro

Search repository
Nakayama, Jun

× Nakayama, Jun

WEKO 22308

Nakayama, Jun

Search repository
Sakai, Keiichi

× Sakai, Keiichi

WEKO 22309

Sakai, Keiichi

Search repository
Kobayashi, Tatsuya

× Kobayashi, Tatsuya

WEKO 22310

Kobayashi, Tatsuya

Search repository
Rutka, James T

× Rutka, James T

WEKO 22311

Rutka, James T

Search repository
信州大学研究者総覧へのリンク
Nakayama, Jun
http://soar-rd.shinshu-u.ac.jp/profile/ja.HCApHFkh.html
出版者
出版者 ELSEVIER SCI LTD
引用
内容記述タイプ Other
内容記述 JOURNAL OF CLINICAL NEUROSCIENCE. 16(12):1615-1618 (2009)
書誌情報 JOURNAL OF CLINICAL NEUROSCIENCE

巻 16, 号 12, p. 1615-1618, 発行日 2009-12
抄録
内容記述タイプ Abstract
内容記述 This study was performed to determine the relationship between p57/Kip2 and the growth of human astrocytomas. Immunohistochemical staining for p57/Kip2, p53, p16, and Ki67 antigen was performed on paraffin-embedded tissue specimens obtained from 36 patients with astrocytoma. Expression of p57/Kip2, p53, p16, and Ki67 antigen was generally increased in association with the astrocytoma tumor grade. Expression of p16 was higher in patients whose tumors express p57/Kip2 in greater than 10% of tumor cells (p < 0.05). Expression of p53 also tended to be higher, but not to a statistically significant extent, in patients whose tumors express p57/Kip2 in greater than 10% of tumor cells. These findings suggest that p57/Kip2 inhibits the growth of human astrocytomas, and may function in parallel with p16 and p53. However, p57/Kip2 is, by itself, insufficient to arrest the cellular proliferation of human astrocytomas.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ ISSN
収録物識別子 0967-5868
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA10958444
PubMed
関連識別子
識別子タイプ PMID
関連識別子 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=19822429
関連名称
関連名称 19822429
DOI
関連識別子
識別子タイプ DOI
関連識別子 http://dx.doi.org/10.1016/j.jocn.2009.05.007
関連名称
関連名称 10.1016/j.jocn.2009.05.007
権利
権利情報 Copyright© 2009 Elsevier Ltd.
著者版フラグ
値 author
WoS
Web of Science
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000271917800017
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