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Reversion-inducing cysteine-rich protein with kazal motifs and matrix metalloproteinase-9 are prognostic markers in skull base chordomas
http://hdl.handle.net/10091/16944
http://hdl.handle.net/10091/16944095cd6cc-bf0b-4f68-a72f-89ac4d94dec3
| 名前 / ファイル | ライセンス | アクション |
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Reversion-inducing_cysteine-rich_protein_kazal_motifs_matrix_metalloproteinase-9.pdf (137.2 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||
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| 公開日 | 2013-04-23 | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Reversion-inducing cysteine-rich protein with kazal motifs and matrix metalloproteinase-9 are prognostic markers in skull base chordomas | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| DOI | ||||||||||||||
| 関連識別子 | https://doi.org/10.1007/s10143-009-0228-y | |||||||||||||
| 関連名称 | 10.1007/s10143-009-0228-y | |||||||||||||
| キーワード | ||||||||||||||
| 主題 | Skull base chordomas, RECK, MMP-2, MMP-9 | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| タイプ | journal article | |||||||||||||
| 著者 |
Rahmah, Nunung Nur
× Rahmah, Nunung Nur
× Sakai, Keiichi
× Nakayama, Jun
× Hongo, Kazuhiro
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| 信州大学研究者総覧へのリンク | ||||||||||||||
| 氏名 | Nakayama, Jun | |||||||||||||
| URL | https://soar-rd.shinshu-u.ac.jp/profile/ja.HCApHFkh.html | |||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||
| 氏名 | Hongo, Kazuhiro | |||||||||||||
| URL | https://soar-rd.shinshu-u.ac.jp/profile/ja.jecFHCkh.html | |||||||||||||
| 出版者 | ||||||||||||||
| 出版者 | SPRINGER | |||||||||||||
| 引用 | ||||||||||||||
| 内容記述 | NEUROSURGICAL REVIEW. 33(2):167-173 (2010) | |||||||||||||
| 書誌情報 |
NEUROSURGICAL REVIEW 巻 33, 号 2, p. 167-173, 発行日 2010-04 |
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| 抄録 | ||||||||||||||
| 内容記述 | Prognosis of chordomas is difficult to predict based solely on histological findings. The purpose of this study was to assess expressions of reversion-inducing cysteine-rich protein with kazal motifs (RECK) and matrix metalloproteinase (MMP)-2, MMP-9 in skull base chordomas and to find out their correlations to outcome. Immunohistochemical study was performed in 19 samples (initial, n = 11; recurrent, n = 8) from 11 patients. The correlations among expression of RECK, MMP-2, MMP-9, and their prognostic values were analyzed. Significant correlation between RECK and MMP-9 was found, but there was no correlation found between MMP-2 and MMP-9. Higher MMP-9 expression significantly influenced outcome. Furthermore, MMP-9/RECK ratio showed significant correlation to outcome, showing their inverse relationship in the disease progress of skull base chordoma. RECK and MMP-9 can be valuable markers to predict prognosis in skull base chordomas. | |||||||||||||
| 資源タイプ（コンテンツの種類） | ||||||||||||||
| ISSN | ||||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||||
| 収録物識別子 | 0344-5607 | |||||||||||||
| 書誌レコードID | ||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||
| 収録物識別子 | AA00324143 | |||||||||||||
| PubMed | ||||||||||||||
| 識別子タイプ | PMID | |||||||||||||
| 関連識別子 | https://pubmed.ncbi.nlm.nih.gov/19862564 | |||||||||||||
| 関連名称 | 19862564 | |||||||||||||
| 権利 | ||||||||||||||
| 権利情報 | The original publication is available at www.springerlink.com | |||||||||||||
| 出版タイプ | ||||||||||||||
| 出版タイプ | AM | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||
| WoS | ||||||||||||||
| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000275472200009 | |||||||||||||
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Rahmah, Nunung Nur, Sakai, Keiichi, Nakayama, Jun, Hongo, Kazuhiro, 2010, Reversion-inducing cysteine-rich protein with kazal motifs and matrix metalloproteinase-9 are prognostic markers in skull base chordomas: SPRINGER, 167–173 p.
