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Although ischemic stroke is recognized as an important manifestation of Fabry\u0027s disease, hemorrhagic stroke is considered to be rare. Here, we report our recent clinical experience with three hemizygous male patients with Fabry\u0027s disease who developed cerebral hemorrhage. One patient had classic type Fabry\u0027s disease with p.Ala37Val mutation and others had cerebrovascular variant with p.Glu66Gln mutation. Degeneration of the cerebral small arteries secondary to deposition of glycosphingolipids and aging, in addition to hypertension and antiplatelet/anticoagulant agents, are considered to be contributing factors for hemorrhage. Fabry\u0027s disease is frequently associated with not only ischemic but also hemorrhagic stroke, especially in elderly patients. 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Although ischemic stroke is recognized as an important manifestation of Fabry\u0027s disease, hemorrhagic stroke is considered to be rare. Here, we report our recent clinical experience with three hemizygous male patients with Fabry\u0027s disease who developed cerebral hemorrhage. One patient had classic type Fabry\u0027s disease with p.Ala37Val mutation and others had cerebrovascular variant with p.Glu66Gln mutation. Degeneration of the cerebral small arteries secondary to deposition of glycosphingolipids and aging, in addition to hypertension and antiplatelet/anticoagulant agents, are considered to be contributing factors for hemorrhage. Fabry\u0027s disease is frequently associated with not only ischemic but also hemorrhagic stroke, especially in elderly patients. 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