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銅錯体の毒性研究(第1報) : 銅セリンと銅サリチル酸
http://hdl.handle.net/10091/804
b1fde80e-2f52-4021-8774-eb275a36e06f
名前 / ファイル | ライセンス | アクション | |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2007-12-27 | |||||
タイトル | ||||||
タイトル | 銅錯体の毒性研究(第1報) : 銅セリンと銅サリチル酸 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Copper complex | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | toxicity | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
その他(別言語等)のタイトル | ||||||
その他のタイトル | Toxicology of Copper Complex (Part I) Copper Serinate and Copper Salicylate | |||||
著者 |
茅原, 紘
× 茅原, 紘× 只左, 弘治× 山本, 正敏× 柴野, 隆司× 内山, 孝一× 池辺, 裕行× 中川, 博司 |
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出版者 | ||||||
出版者 | 信州大学農学部 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 信州大学農学部紀要. 28(2): 141-154 (1991) | |||||
書誌情報 |
信州大学農学部紀要 巻 28, 号 2, p. 141-154, 発行日 1991-12-25 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Cu-serineおよびCu-salicylate,ならびにそれらの合成に用いたCu(OH)2およびCu(NO3)2をそれぞれ50mg/kg,1群6匹の成熟雌ラットに7日間連日皮下投与し,その毒性を検討した。1) Cu-serine群の1匹,Cu(NO3)2群の4匹が死亡した。2) Cu-serine群の2匹で後址をつっぱって腰部をもちあげる,いわゆるロードシス反射を示唆する行動が観察された。3) Cu-serine群およびCu(NO3)2群において著明な体重減少が認められた。4) すべての銅化合物群で溶血性貧血が認められた。5) 肝細胞および腎尿細管上皮の変性・壊死がCu-serine群およびCu(NO3)2群で,クッパー星細胞腫大がすべての銅化合物で認められた。6) Cu-serine群およびCu(NO3)2群で胸腺のリンパ球減少が特に著しかった。7) これらの毒性効果は,明らかに銅そのものに起因しており,Cu-salicylateおよびCu(OH)2よりもCu-serineおよびCu(NO3)2において強かった。 | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0583-0621 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00121352 |