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ヒト,ウサギおよびウシ臓器由来の組織因子を用いた第Ⅶ因子アミダーゼ活性の比較
http://hdl.handle.net/10091/5204
http://hdl.handle.net/10091/520406cce084-fa07-4201-b3e9-4c148ab728b0
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||
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公開日 | 2010-03-01 | |||||||||
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タイトル | ヒト,ウサギおよびウシ臓器由来の組織因子を用いた第Ⅶ因子アミダーゼ活性の比較 | |||||||||
タイトル | ||||||||||
タイトル | Comparison of 3 kinds of tissue factors from human brain, rabbit brain/lung and ox brain for factor Ⅶ amidolitic activity assay | |||||||||
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言語 | jpn | |||||||||
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主題 | factor Ⅶ, amidolytic activity, chromogenic substrate, tissue factor 第Ⅶ因子, アミダーゼ活性, 合成基質, 組織因子 |
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資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||
タイプ | departmental bulletin paper | |||||||||
著者 |
高宮, 脩
× 高宮, 脩
× 加藤, 亮二
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出版者 | ||||||||||
出版者 | 信州大学医療技術短期大学部 | |||||||||
引用 | ||||||||||
内容記述 | 紀要 21: 127-132(1996) | |||||||||
書誌情報 |
紀要 巻 21, p. 127-132, 発行日 1996-02-29 |
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抄録 | ||||||||||
内容記述 | A comparison was made among factor VII amidolytic activities on a chromogenic substrate assay using tissue factors from human brain (HB-TF), rabbit brain/lung (RB/L-TF) and bovine brain (BBITF). Factor VII amidolytic activities using HB-TF showed linearity between absorbance (A₄₀₅nm) and diluent concentration of normal pooled-plasma on log-log paper, but not RB/L-TF and BB-TF. In normal individuals, factor VII amidolytic activities using three tissue factors were given close agreement (p>0.05). In patients receiving stabilized oral anticoagulation, factor VII amidolytic activities using RB/L-TF (r=0.828) and BB-TF (r=0.742) correlated well with that using HB-TF, respectively. Factor VII amidolytic activities using RB/L-TF (62.7±23.8%.) Were somewhat higher than those from HB-TF (56.1±22.50/.) and BB-TF (56.1±22.7%). In all kinds of disease containing liver disease, factor VII amidolytic activities using RB/LTF (r=0.771) and BB-TF (r=0.769) correlated well with that using HB-TF, although factor VII amidolytic activities using BB-TF (108.8±34.7%) were somewhat higher than those from HB-TF (92.8±35.2%) and RB/L-TF (95.0±31.7%), In eleven factor VII deficiencies with CRM⁻, factor VII amidolytic activities using RB/L-TF (3.9±3.0%) was somewhat higher than those using remaining two tissue factors, HB-TF (2.1±1.8%) and BB-TF (2.4±1.4%). | |||||||||
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収録物識別子タイプ | ISSN | |||||||||
収録物識別子 | 0385-1982 | |||||||||
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収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AN10402438 |
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高宮, 脩, 加藤, 亮二, 1996, ヒト,ウサギおよびウシ臓器由来の組織因子を用いた第Ⅶ因子アミダーゼ活性の比較: 信州大学医療技術短期大学部, 127–132 p.
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