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High concentrations of omega-3 fatty acids are associated with the development of atrial fibrillation in the Japanese population
http://hdl.handle.net/10091/17344
http://hdl.handle.net/10091/17344a6941278-26c0-4ec2-81ff-98e9ecfee9b7
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
High_Concentration_of_Omega3Fatty_Acids_HV_final.pdf (221.7 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-01-21 | |||||
| タイトル | ||||||
| タイトル | High concentrations of omega-3 fatty acids are associated with the development of atrial fibrillation in the Japanese population | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| DOI | ||||||
| 関連名称 | 10.1007/s00380-012-0264-3 | |||||
| キーワード | ||||||
| 主題 | Atrial fibrillation, Fatty acids, Omega-3 fatty acids, Risk factors | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Tomita, Takeshi
× Tomita, Takeshi× Hata, Takeki× Takeuchi, Takahiro× Oguchi, Yasutaka× Okada, Ayako× Aizawa, Kazunori× Koshikawa, Megumi× Otagiri, Kyuhachi× Motoki, Hirohiko× Kasai, Hiroki× Izawa, Atsushi× Koyama, Jun× Hongo, Minoru× Ikeda, Uichi |
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| 信州大学研究者総覧へのリンク | ||||||
| 表示名 | Okada, Ayako | |||||
| URL | https://soar-rd.shinshu-u.ac.jp/profile/ja.ZUnNPUym.html | |||||
| 信州大学研究者総覧へのリンク | ||||||
| 表示名 | Motoki, Hirohiko | |||||
| URL | https://soar-rd.shinshu-u.ac.jp/profile/ja.ymfFgpkh.html | |||||
| 信州大学研究者総覧へのリンク | ||||||
| 表示名 | Izawa, Atsushi | |||||
| URL | https://soar-rd.shinshu-u.ac.jp/profile/ja.yNnVgpkh.html | |||||
| 出版者 | ||||||
| 出版者 | SPRINGER | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | HEART AND VESSELS. 28(4):497-504 (2013) | |||||
| 書誌情報 |
HEART AND VESSELS 巻 28, 号 4, p. 497-504, 発行日 2013-06 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The favorable effect of fish oils rich in n-3 polyunsaturated fatty acids (PUFAs) on the development of atrial fibrillation (AF) is controversial. The relationship between the serum concentrations of n-3 PUFAs and the incidence of AF is unclear; therefore, in the present study, we aimed to elucidate this relationship. We evaluated the serum concentrations of n-3 PUFAs in 110 patients with AF, 46 patients with ischemic heart disease (IHD) and no AF, and 36 healthy volunteers. Thirty-six patients had a history of IHD (IHD-AF group) and 74 did not (L-AF group). The eicosapentaenoic acid (EPA) levels in the L-AF group were higher than those in the IHD-AF and control groups (117 +/- A 64, 76 +/- A 30, and 68 +/- A 23 mu g/ml, respectively); the docosahexaenoic acid (DHA) levels showed the same pattern (170 +/- A 50, 127 +/- A 27, and 126 +/- A 35 mu g/ml, respectively). In both the L-AF and IHD-AF groups, the EPA levels in patients with persistent and permanent AF were higher than those in patients with paroxysmal AF (L-AF 131 +/- A 74 vs. 105 +/- A 51 mu g/ml; IHD-AF 82 +/- A 28 vs 70 +/- A 33 mu g/ml). Multivariate analysis showed that cases of AF were associated with higher levels of EPA but not DHA. In this Japanese population study, the EPA and DHA levels in patients with L-AF were higher than those in normal subjects. In particular, the EPA level was associated with the incidence of AF. These findings suggest that an excess of EPA might be a precipitating factor of AF. | |||||
| 資源タイプ（コンテンツの種類） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Article | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0910-8327 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA10452161 | |||||
| PubMed | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | https://pubmed.ncbi.nlm.nih.gov/22696184 | |||||
| 関連名称 | 22696184 | |||||
| 権利 | ||||||
| 権利情報 | The original publication is available at www.springerlink.com | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| WoS | ||||||
| 表示名 | Web of Science | |||||
| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000321768700011 | |||||
