| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2014-01-21 |
| タイトル |
|
|
タイトル |
High concentrations of omega-3 fatty acids are associated with the development of atrial fibrillation in the Japanese population |
| 言語 |
|
|
言語 |
eng |
| DOI |
|
|
|
関連識別子 |
https://doi.org/10.1007/s00380-012-0264-3 |
|
|
関連名称 |
10.1007/s00380-012-0264-3 |
| キーワード |
|
|
主題 |
Atrial fibrillation, Fatty acids, Omega-3 fatty acids, Risk factors |
| 資源タイプ |
|
|
資源 |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 著者 |
Tomita, Takeshi
Hata, Takeki
Takeuchi, Takahiro
Oguchi, Yasutaka
Okada, Ayako
Aizawa, Kazunori
Koshikawa, Megumi
Otagiri, Kyuhachi
Motoki, Hirohiko
Kasai, Hiroki
Izawa, Atsushi
Koyama, Jun
Hongo, Minoru
Ikeda, Uichi
|
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Okada, Ayako |
|
URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.ZUnNPUym.html |
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Motoki, Hirohiko |
|
URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.ymfFgpkh.html |
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Izawa, Atsushi |
|
URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.yNnVgpkh.html |
| 出版者 |
|
|
出版者 |
SPRINGER |
| 引用 |
|
|
内容記述 |
HEART AND VESSELS. 28(4):497-504 (2013) |
| 書誌情報 |
HEART AND VESSELS
巻 28,
号 4,
p. 497-504,
発行日 2013-06
|
| 抄録 |
|
|
内容記述 |
The favorable effect of fish oils rich in n-3 polyunsaturated fatty acids (PUFAs) on the development of atrial fibrillation (AF) is controversial. The relationship between the serum concentrations of n-3 PUFAs and the incidence of AF is unclear; therefore, in the present study, we aimed to elucidate this relationship. We evaluated the serum concentrations of n-3 PUFAs in 110 patients with AF, 46 patients with ischemic heart disease (IHD) and no AF, and 36 healthy volunteers. Thirty-six patients had a history of IHD (IHD-AF group) and 74 did not (L-AF group). The eicosapentaenoic acid (EPA) levels in the L-AF group were higher than those in the IHD-AF and control groups (117 +/- A 64, 76 +/- A 30, and 68 +/- A 23 mu g/ml, respectively); the docosahexaenoic acid (DHA) levels showed the same pattern (170 +/- A 50, 127 +/- A 27, and 126 +/- A 35 mu g/ml, respectively). In both the L-AF and IHD-AF groups, the EPA levels in patients with persistent and permanent AF were higher than those in patients with paroxysmal AF (L-AF 131 +/- A 74 vs. 105 +/- A 51 mu g/ml; IHD-AF 82 +/- A 28 vs 70 +/- A 33 mu g/ml). Multivariate analysis showed that cases of AF were associated with higher levels of EPA but not DHA. In this Japanese population study, the EPA and DHA levels in patients with L-AF were higher than those in normal subjects. In particular, the EPA level was associated with the incidence of AF. These findings suggest that an excess of EPA might be a precipitating factor of AF. |
| 資源タイプ（コンテンツの種類） |
|
| ISSN |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0910-8327 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA10452161 |
| PubMed |
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|
識別子タイプ |
PMID |
|
|
関連識別子 |
https://pubmed.ncbi.nlm.nih.gov/22696184 |
|
|
関連名称 |
22696184 |
| 権利 |
|
|
権利情報 |
The original publication is available at www.springerlink.com |
| 出版タイプ |
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|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| WoS |
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|
URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000321768700011 |
High_Concentration_of_Omega3Fatty_Acids_HV_final.pdf (221.7 kB)
