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  1. 055 医学部附属病院
  2. 0551 学術論文

High concentrations of omega-3 fatty acids are associated with the development of atrial fibrillation in the Japanese population

http://hdl.handle.net/10091/17344
http://hdl.handle.net/10091/17344
a6941278-26c0-4ec2-81ff-98e9ecfee9b7
名前 / ファイル ライセンス アクション
High_Concentration_of_Omega3Fatty_Acids_HV_final.pdf High_Concentration_of_Omega3Fatty_Acids_HV_final.pdf (221.7 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-01-21
タイトル
言語 en
タイトル High concentrations of omega-3 fatty acids are associated with the development of atrial fibrillation in the Japanese population
言語
言語 eng
キーワード
主題Scheme Other
主題 Atrial fibrillation
キーワード
主題Scheme Other
主題 Fatty acids
キーワード
主題Scheme Other
主題 Omega-3 fatty acids
キーワード
主題Scheme Other
主題 Risk factors
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Tomita, Takeshi

× Tomita, Takeshi

WEKO 22234

en Tomita, Takeshi

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Hata, Takeki

× Hata, Takeki

WEKO 22235

en Hata, Takeki

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Takeuchi, Takahiro

× Takeuchi, Takahiro

WEKO 22236

en Takeuchi, Takahiro

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Oguchi, Yasutaka

× Oguchi, Yasutaka

WEKO 22237

en Oguchi, Yasutaka

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Okada, Ayako

× Okada, Ayako

WEKO 22238

en Okada, Ayako

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Aizawa, Kazunori

× Aizawa, Kazunori

WEKO 22239

en Aizawa, Kazunori

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Koshikawa, Megumi

× Koshikawa, Megumi

WEKO 22240

en Koshikawa, Megumi

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Otagiri, Kyuhachi

× Otagiri, Kyuhachi

WEKO 22241

en Otagiri, Kyuhachi

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Motoki, Hirohiko

× Motoki, Hirohiko

WEKO 22242

en Motoki, Hirohiko

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Kasai, Hiroki

× Kasai, Hiroki

WEKO 22243

en Kasai, Hiroki

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Izawa, Atsushi

× Izawa, Atsushi

WEKO 22244

en Izawa, Atsushi

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Koyama, Jun

× Koyama, Jun

WEKO 22245

en Koyama, Jun

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Hongo, Minoru

× Hongo, Minoru

WEKO 22246

en Hongo, Minoru

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Ikeda, Uichi

× Ikeda, Uichi

WEKO 22247

en Ikeda, Uichi

Search repository
信州大学研究者総覧へのリンク
氏名 Okada, Ayako
URL https://soar-rd.shinshu-u.ac.jp/profile/ja.ZUnNPUym.html
信州大学研究者総覧へのリンク
氏名 Motoki, Hirohiko
URL https://soar-rd.shinshu-u.ac.jp/profile/ja.ymfFgpkh.html
信州大学研究者総覧へのリンク
氏名 Izawa, Atsushi
URL https://soar-rd.shinshu-u.ac.jp/profile/ja.yNnVgpkh.html
出版者
出版者 SPRINGER
引用
内容記述タイプ Other
内容記述 HEART AND VESSELS. 28(4):497-504 (2013)
書誌情報 HEART AND VESSELS

巻 28, 号 4, p. 497-504, 発行日 2013-06
抄録
内容記述タイプ Abstract
内容記述 The favorable effect of fish oils rich in n-3 polyunsaturated fatty acids (PUFAs) on the development of atrial fibrillation (AF) is controversial. The relationship between the serum concentrations of n-3 PUFAs and the incidence of AF is unclear; therefore, in the present study, we aimed to elucidate this relationship. We evaluated the serum concentrations of n-3 PUFAs in 110 patients with AF, 46 patients with ischemic heart disease (IHD) and no AF, and 36 healthy volunteers. Thirty-six patients had a history of IHD (IHD-AF group) and 74 did not (L-AF group). The eicosapentaenoic acid (EPA) levels in the L-AF group were higher than those in the IHD-AF and control groups (117 +/- A 64, 76 +/- A 30, and 68 +/- A 23 mu g/ml, respectively); the docosahexaenoic acid (DHA) levels showed the same pattern (170 +/- A 50, 127 +/- A 27, and 126 +/- A 35 mu g/ml, respectively). In both the L-AF and IHD-AF groups, the EPA levels in patients with persistent and permanent AF were higher than those in patients with paroxysmal AF (L-AF 131 +/- A 74 vs. 105 +/- A 51 mu g/ml; IHD-AF 82 +/- A 28 vs 70 +/- A 33 mu g/ml). Multivariate analysis showed that cases of AF were associated with higher levels of EPA but not DHA. In this Japanese population study, the EPA and DHA levels in patients with L-AF were higher than those in normal subjects. In particular, the EPA level was associated with the incidence of AF. These findings suggest that an excess of EPA might be a precipitating factor of AF.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 0910-8327
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA10452161
PubMed
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/22696184
関連名称 22696184
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1007/s00380-012-0264-3
関連名称 10.1007/s00380-012-0264-3
権利
権利情報 The original publication is available at www.springerlink.com
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000321768700011
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